Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Mucormycosis: Botanical Insights Into The Major Causative Agents

Version 1 : Received: 7 June 2021 / Approved: 8 June 2021 / Online: 8 June 2021 (13:36:36 CEST)

How to cite: Anjum, N.A. Mucormycosis: Botanical Insights Into The Major Causative Agents. Preprints 2021, 2021060218 (doi: 10.20944/preprints202106.0218.v1). Anjum, N.A. Mucormycosis: Botanical Insights Into The Major Causative Agents. Preprints 2021, 2021060218 (doi: 10.20944/preprints202106.0218.v1).

Abstract

Mucormycosis (previously called zygomycosis or phycomycosis), an aggressive, life-threatening infection is further aggravating the human health-impact of the devastating COVID-19 pandemic. Additionally, a great deal of mostly misleading discussion is focused also on the aggravation of the COVID-19 accrued impacts due to the white and yellow fungal diseases. In addition to the knowledge of important risk factors, modes of spread, pathogenesis and host defences, a critical discussion on the botanical insights into the main causative agents of mucormycosis in the current context is very imperative. Given above, in this paper: (i) general background of the mucormycosis and COVID-19 is briefly presented; (ii) overview of fungi is presented, the major beneficial and harmful fungi are highlighted; and also the major ways of fungal infections such as mycosis, mycotoxicosis, and mycetismus are enlightened; (iii) the major causative agents of mucormycosis are critically discussed; (iv) the systematic position, occurrence, structure, and the major modes of reproduction are summarized for Rhizopus sp. and Mucor sp., the major causative agents of mucormycosis; (v) the other causative agents of mucormycosis includes Cunninghamella bertholletiae, Apophysomyces elegans, Lichtheimia (Absidia), Saksenaea, and Rhizomucor pusillus are briefly introduced; (vi) facts related with the infection-misnomers based on fungi colour are also highlighted; and lastly, (vii) the major take-home message and clues for future research on the subject are listed.

Subject Areas

Mucormycosis; Causative agents; Rhizopus sp.; Mucor sp.; Botanical insights; COVID-19

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