Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

The Gut Microbiome in Western and Indigenous Cultures

Version 1 : Received: 5 April 2021 / Approved: 6 April 2021 / Online: 6 April 2021 (12:40:04 CEST)

How to cite: Das, S.; Andrighettti, T.; Sabino, J.; Korcsmaros, T.; Rohman Khan, M.; Vermeire, S.; Sudhakar, P. The Gut Microbiome in Western and Indigenous Cultures. Preprints 2021, 2021040175 (doi: 10.20944/preprints202104.0175.v1). Das, S.; Andrighettti, T.; Sabino, J.; Korcsmaros, T.; Rohman Khan, M.; Vermeire, S.; Sudhakar, P. The Gut Microbiome in Western and Indigenous Cultures. Preprints 2021, 2021040175 (doi: 10.20944/preprints202104.0175.v1).

Abstract

The mammalian gut ecosystem plays critical roles in multiple functions related to health and homeostasis. In many cases, disturbances in the gut ecosystem are associated with a large number of metabolic and chronic diseases and disorders such as diabetes, cancer, and obesity. A diverse community of microorganisms ranging from viruses to bacteria comprise the gut microbiota, which is often considered as an organ in itself. Recent studies have profiled the influence of lifestyles and dietary behavior by comparing the gut microbiome of populations with different cultural underpinnings. In this review, we provide an overview of the studies which report the influence on the gut microbial composition of dietary and lifestyle patterns in different contexts such as western industrialized countries and indigenous cultures (corresponding to different lifestyle gradients such as hunter-gatherers and pastoralists) and how this association may influence health and disease.

Subject Areas

Gut microbiome; Western and indigenous/traditional cultures; gut health; disease; lifestyle; novel microbials

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