Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Long-Term Iron and Vitamin B12 Deficiency are Present After Bariatric Surgery, Despite the Widespread Use of Supplements.

Version 1 : Received: 18 February 2021 / Approved: 19 February 2021 / Online: 19 February 2021 (14:36:21 CET)

How to cite: Lombardo, M.; Franchi, A.; Biolcati Rinaldi, R.; Rizzo, G.; D'Adamo, M.; Guglielmi, V.; Bellia, A.; Padua, E.; Caprio, M.; Sbraccia, P. Long-Term Iron and Vitamin B12 Deficiency are Present After Bariatric Surgery, Despite the Widespread Use of Supplements.. Preprints 2021, 2021020445 (doi: 10.20944/preprints202102.0445.v1). Lombardo, M.; Franchi, A.; Biolcati Rinaldi, R.; Rizzo, G.; D'Adamo, M.; Guglielmi, V.; Bellia, A.; Padua, E.; Caprio, M.; Sbraccia, P. Long-Term Iron and Vitamin B12 Deficiency are Present After Bariatric Surgery, Despite the Widespread Use of Supplements.. Preprints 2021, 2021020445 (doi: 10.20944/preprints202102.0445.v1).

Abstract

Long-term nutritional studies in subjects undergoing bariatric surgery that have assessed weight regain and nutritional deficiencies are few. In this study, we report data 8 years after surgery on weight loss, use of dietary supplements and deficit of micronutrients in a cohort of patients from five centres in central and northern Italy. The study group consisted of 52 subjects (age: 38.1±10.6 yrs, 42 females): 16 patients had Roux-en-Y gastric bypass (RYGB), 25 patients sleeve gastrectomy (LSG) and 11 subjects adjustable gastric banding (AGB). All three bariatric procedures led to sustained weight loss: average percentage excess weight loss, defined as weight loss divided by excess weight based on ideal body weight was 60.6%±32.3. 80.7% of subjects (72.7%, AGB; 76%, SG; 93.7%, RYGB) reported at least one nutritional deficiency: iron (F 64.3% vs. M 30%), vitamin B12 (F 16.6% vs. M 10%), calcium (F 33.3% vs. M 0%) and vitamin D (F 38.1% vs. M 60%). Average weight loss was constant in RYGB and SG subjects from the third year after surgery. Long-term nutritional deficiencies were greater than the general population among men for iron and among women for vitamin B12.

Subject Areas

Iron; Vitamin D; Vitamin B12; Roux-en-Y gastric bypass; Sleeve gastrectomy; Adjustable gastric banding; nutritional deficiency; bariatric surgery

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