Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

A Systematic Review of Literature on Representation of Racial and Ethnic Minority Groups in Clinical Nutrition Interventions

Version 1 : Received: 28 January 2021 / Approved: 29 January 2021 / Online: 29 January 2021 (14:34:17 CET)

A peer-reviewed article of this Preprint also exists.

Journal reference: Advances in Nutrition 2022
DOI: 10.1093/advances/nmac002


There is a disproportionate increase in the incidence of diet-related cardiometabolic disorders in racial and ethnic minority groups. This systematic review examines the extent to which diet-induced changes in health outcomes have been discussed by race or ethnicity in randomized controlled trials recruiting both minority and non-Hispanic White groups. Databases i.e. PubMed, Cochrane library and Web of Science were searched up to November 2019. Studies that discussed effects of defined dietary interventions on health outcomes by racial or ethnic minority group vs. non-Hispanic Whites (n=29) were included in the review. Most studies were conducted in Black vs. White people testing effects of energy restriction, macronutrient modification, sodium reduction, or variations of the Dietary Approaches to Stop Hypertension (DASH) diet on cardiometabolic outcomes. There was limited focus on other minority groups. Evidence suggests greater blood pressure reduction for Black people compared to Whites particularly on DASH (or similar) diets. Overall, there was limited consideration for group-specific eating patterns and diet acceptability in most studies. Adequately powered studies are needed for accurate interpretation of race by diet effects. With emerging precision nutrition initiatives, it is imperative to ensure adequate representation of racial and ethnic subgroups for addressing nutrition-related health disparities.


Health disparities; Underrepresented groups; Diet; Race

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