Working Paper Review Version 1 This version is not peer-reviewed

The Immune System View of the Coronavirus SARS-CoV-2

Version 1 : Received: 2 December 2020 / Approved: 3 December 2020 / Online: 3 December 2020 (09:20:35 CET)

How to cite: Celardo, I.; Pace, L.; Cifaldi, L.; Gaudio, C.; Barnaba, V. The Immune System View of the Coronavirus SARS-CoV-2. Preprints 2020, 2020120075 Celardo, I.; Pace, L.; Cifaldi, L.; Gaudio, C.; Barnaba, V. The Immune System View of the Coronavirus SARS-CoV-2. Preprints 2020, 2020120075

Abstract

Knowing the “point of view” of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection.

Subject Areas

COVID-19; SARS-CoV-2; vaccine; coronavirus; monoclonal antibodies

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