Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Synthesis of Silver Modified Bioactive Glassy Materials with Antibacterial Properties via Facile and Low-Temperature Route

Version 1 : Received: 19 October 2020 / Approved: 20 October 2020 / Online: 20 October 2020 (08:34:22 CEST)

A peer-reviewed article of this Preprint also exists.

Gonzalo-Juan, I.; Xie, F.; Becker, M.; Tulyaganov, D.U.; Ionescu, E.; Lauterbach, S.; De Angelis Rigotti, F.; Fischer, A.; Riedel, R. Synthesis of Silver Modified Bioactive Glassy Materials with Antibacterial Properties via Facile and Low-Temperature Route. Materials 2020, 13, 5115. Gonzalo-Juan, I.; Xie, F.; Becker, M.; Tulyaganov, D.U.; Ionescu, E.; Lauterbach, S.; De Angelis Rigotti, F.; Fischer, A.; Riedel, R. Synthesis of Silver Modified Bioactive Glassy Materials with Antibacterial Properties via Facile and Low-Temperature Route. Materials 2020, 13, 5115.

Journal reference: Materials 2020, 13, 5115
DOI: 10.3390/ma13225115

Abstract

There is an increasing clinical need to develop novel biomaterials that combine regenerative and biocidal properties. In this work, we present the preparation of silver /silica based glassy bioactive (ABG) compositions via a facile, fast (20h), and low temperature (80 °C) approach and their characterization. The fabrication process included the synthesis of the bioactive glass (BG) particles followed by the surface modification of the bioactive glass with silver nanoparticles. The microstructural features of ABG samples before and after exposure to simulated body fluid (SBF) as well as their ion release behavior during SBF test were evaluated using infrared spectrometry (FTIR), ultraviolet- visible (UV-Vis) spectroscopy, X-ray diffraction (XRD), electron microscopies (TEM and SEM) and optical emission spectroscopy (OES). The antibacterial properties of the experimental compositions were tested against Escherichia coli (E. coli). The results indicated that the prepared ABG materials possess antibacterial activity against E. coli, which is directly correlated with the glass surface modification.

Subject Areas

Bioactive glass; antibacterial; silver; nanocomposites; E. coli; ion release

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