Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Effects of Mosquito Biology on Modeled Chikungunya Virus Invasion Potential in Florida

Version 1 : Received: 17 July 2020 / Approved: 19 July 2020 / Online: 19 July 2020 (14:40:22 CEST)

A peer-reviewed article of this Preprint also exists.

Lord, C.C.; Lounibos, L.P.; Pohedra, J.J.; Alto, B.W. Effects of Mosquito Biology on Modeled Chikungunya Virus Invasion Potential in Florida. Viruses 2020, 12, 830. Lord, C.C.; Lounibos, L.P.; Pohedra, J.J.; Alto, B.W. Effects of Mosquito Biology on Modeled Chikungunya Virus Invasion Potential in Florida. Viruses 2020, 12, 830.

Journal reference: Viruses 2020, 12, 830
DOI: 10.3390/v12080830

Abstract

: Arboviruses transmitted by Aedes aegypti and Ae. albopictus have been introduced to Florida on many occasions. Infrequently, these introductions lead to sporadic local transmission and, more rarely, sustained local transmission. Both mosquito species are present in Florida, with spatio-temporal variation in population composition. We developed a 2-vector compartmental, deterministic model to investigate factors influencing Chikungunya virus (CHIKV) establishment. The model includes a non-linear, temperature-dependent mosquito mortality function based on minimum mortality in a central temperature region. Latin Hypercube sampling was used to generate parameter sets used to simulate transmission dynamics, following the introduction of one infected human. The analysis was repeated for 3 values of the mortality function central temperature. Mean annual temperature was consistently important in the likelihood of epidemics, and epidemics increased as the central temperature increased. Ae. albopictus recruitment was influential at the lowest central temperature while Ae. aegypti recruitment was influential at higher central temperatures. Our results indicate that the likelihood of CHIKV establishment may vary, but overall Florida is permissive for introductions. Model outcomes were sensitive to the specifics of mosquito mortality. Mosquito biology parameters are variable, and improved understanding of this variation will improve our ability to predict the outcome of introductions.

Subject Areas

Chikungunya virus; invasion; transmission dynamics; Aedes aegypti; Aedes albopictus; mathematical model

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.