Version 1
: Received: 15 July 2020 / Approved: 16 July 2020 / Online: 16 July 2020 (04:17:32 CEST)
How to cite:
Ghidini, M.; Indini, A.; Rijavec, E.; Bareggi, C.; Cattaneo, M.; Galassi, B.; Gambini, D.; Grossi, F. The Appropriateness of Invasive Ventilation in COVID-19 Positive Cancer Patients: The Hardest Decision for Oncologists. Preprints2020, 2020070341. https://doi.org/10.20944/preprints202007.0341.v1
Ghidini, M.; Indini, A.; Rijavec, E.; Bareggi, C.; Cattaneo, M.; Galassi, B.; Gambini, D.; Grossi, F. The Appropriateness of Invasive Ventilation in COVID-19 Positive Cancer Patients: The Hardest Decision for Oncologists. Preprints 2020, 2020070341. https://doi.org/10.20944/preprints202007.0341.v1
Ghidini, M.; Indini, A.; Rijavec, E.; Bareggi, C.; Cattaneo, M.; Galassi, B.; Gambini, D.; Grossi, F. The Appropriateness of Invasive Ventilation in COVID-19 Positive Cancer Patients: The Hardest Decision for Oncologists. Preprints2020, 2020070341. https://doi.org/10.20944/preprints202007.0341.v1
APA Style
Ghidini, M., Indini, A., Rijavec, E., Bareggi, C., Cattaneo, M., Galassi, B., Gambini, D., & Grossi, F. (2020). The Appropriateness of Invasive Ventilation in COVID-19 Positive Cancer Patients: The Hardest Decision for Oncologists. Preprints. https://doi.org/10.20944/preprints202007.0341.v1
Chicago/Turabian Style
Ghidini, M., Donatella Gambini and Francesco Grossi. 2020 "The Appropriateness of Invasive Ventilation in COVID-19 Positive Cancer Patients: The Hardest Decision for Oncologists" Preprints. https://doi.org/10.20944/preprints202007.0341.v1
Abstract
Over the last two months, as oncology specialists, we have frequently been contacted for estimating prognosis for cancer patients affected by COVID-19 infection. Until now, there have been no clear markers to guide decision making regarding the appropriateness of invasive ventilation in cancer patients affected by COVID-19 infection. Therefore, we developed a practical tool encompassing a prognostic score. We aimed at identifying a subgroup of patients likely to have a better outcome and therefore may be potential candidates for invasive ventilation, "The Milano Policlinico ONCOVID-ICU score". The score is composed by three groups of variables: patient’s characteristics such as sex, age, BMI and comorbidities; oncological variables (treatment intent, life expectancy, on or off-treatment status) and clinical parameters in association with laboratory values (SOFA score and D-dimer). The SOFA score includes six different clinical parameters and during the first few days of ICU admissions has an important prognostic role. The oncological history should never represent, per se, a contraindication to intensive care and must be considered together with other variables, such as laboratory values, clinical parameters and patient characteristics, in order to make the hardest but best possible choice. The Milano Policlinico ONCOVID-ICU score, to our knowledge, is the first prognostic score proposed in this setting of patients and may be a useful tool to assess the prognosis of cancer patients being in this critical condition.
Medicine and Pharmacology, Oncology and Oncogenics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
