Preprint Concept Paper Version 1 Preserved in Portico This version is not peer-reviewed

Infection-Genomics of COVID-19: Are Some Communities Resistant?

Version 1 : Received: 18 April 2020 / Approved: 19 April 2020 / Online: 19 April 2020 (01:35:58 CEST)
Version 2 : Received: 2 May 2020 / Approved: 4 May 2020 / Online: 4 May 2020 (19:12:33 CEST)
Version 3 : Received: 16 May 2020 / Approved: 17 May 2020 / Online: 17 May 2020 (14:51:39 CEST)

How to cite: Kini, R.M. Infection-Genomics of COVID-19: Are Some Communities Resistant?. Preprints 2020, 2020040310. https://doi.org/10.20944/preprints202004.0310.v1 Kini, R.M. Infection-Genomics of COVID-19: Are Some Communities Resistant?. Preprints 2020, 2020040310. https://doi.org/10.20944/preprints202004.0310.v1

Abstract

The 2019-Novel Coronavirus has currently gripped the world in terror, affecting 210 countries and territories as of April 17, 2020. Originating from Wuhan, Hubei province, China, the virus has spread so rapidly throughout the world and has already claimed 144,700 lives and is currently afflicting 2.17 million people. The US has over 677,000 confirmed cases of COVID-19, followed by Spain, Italy, France, Germany, UK and China. On careful inspection of the COVID-19 statistics, a peculiar unsettling trend becomes apparent. Here, I will highlight this trend and propose the importance of infection-genomics (sankramikogenomics), in understanding the susceptibility to COVID-19 and the severity of disease progress.

Keywords

ACE2; Spike protein; SARS-CoV2; death rate; polymorphism; isoform variant

Subject

Biology and Life Sciences, Virology

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