Working Paper Review Version 2 This version is not peer-reviewed

Revisiting the Stress Concept in the Context of Solid Tumors Prognostic: A Role for the Stress Granules?

Version 1 : Received: 15 January 2020 / Approved: 17 January 2020 / Online: 17 January 2020 (08:32:50 CET)
Version 2 : Received: 6 April 2020 / Approved: 7 April 2020 / Online: 7 April 2020 (01:56:12 CEST)

How to cite: Aulas, A.; Finetti, P.; Lyons, S.; Bertucci, F.; Birnbaum, D.; Acquaviva, C.; Mamessier, E. Revisiting the Stress Concept in the Context of Solid Tumors Prognostic: A Role for the Stress Granules?. Preprints 2020, 2020010180 Aulas, A.; Finetti, P.; Lyons, S.; Bertucci, F.; Birnbaum, D.; Acquaviva, C.; Mamessier, E. Revisiting the Stress Concept in the Context of Solid Tumors Prognostic: A Role for the Stress Granules?. Preprints 2020, 2020010180

Abstract

Stress Granules formation is a pro-survival mechanism helping cells to cope with environmental challenges. Stress Granules have been studied for two decades in fundamental research, and are now being examined in the context of human pathogenesis. Here, we review studies highlighting stress granules’ involvement in cancer development through translational pattern modification.

Subject Areas

stress granules; G3BP1; G3BP2; Caprin-1; USP10; TIA1; TIAR; cancer prognosis; biomarker; metastasis; resistance; cell death; pro-survival properties

Comments (1)

Comment 1
Received: 7 April 2020
Commenter: Anais Aulas
Commenter's Conflict of Interests: Author
Comment: Revisions are throughout the manuscript.
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