Revisiting the Stress Concept in the Context of Solid Tumors Prognostic: A Role for the Stress Granules?

Anais Aulas; Pascal Finetti; Shawn Lyons; François Bertucci; Daniel Birnbaum; Claire Acquaviva; Emilie Mamessier

Version 1 : Received: 15 January 2020 / Approved: 17 January 2020 / Online: 17 January 2020 (08:32:50 CET)
Version 2 : Received: 6 April 2020 / Approved: 7 April 2020 / Online: 7 April 2020 (01:56:12 CEST)

How to cite: Aulas, A.; Finetti, P.; Lyons, S.; Bertucci, F.; Birnbaum, D.; Acquaviva, C.; Mamessier, E. Revisiting the Stress Concept in the Context of Solid Tumors Prognostic: A Role for the Stress Granules?. Preprints 2020, 2020010180 Aulas, A.; Finetti, P.; Lyons, S.; Bertucci, F.; Birnbaum, D.; Acquaviva, C.; Mamessier, E. Revisiting the Stress Concept in the Context of Solid Tumors Prognostic: A Role for the Stress Granules?. Preprints 2020, 2020010180

Abstract

Stress Granules formation is a pro-survival mechanism helping cells to cope with environmental challenges. Stress Granules have been studied for two decades in fundamental research, and are now being examined in the context of human pathogenesis. Here, we review studies highlighting stress granules’ involvement in cancer development through translational pattern modification.

Keywords

stress granules; G3BP1; G3BP2; Caprin-1; USP10; TIA1; TIAR; cancer prognosis; biomarker; metastasis; resistance; cell death; pro-survival properties

Subject

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Revisiting the Stress Concept in the Context of Solid Tumors Prognostic: A Role for the Stress Granules?

Abstract

Keywords

Subject

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