Submitted:
06 April 2020
Posted:
07 April 2020
You are already at the latest version
Abstract
Stress Granules formation is a pro-survival mechanism helping cells to cope with environmental challenges. Stress Granules have been studied for two decades in fundamental research, and are now being examined in the context of human pathogenesis. Here, we review studies highlighting stress granules’ involvement in cancer development through translational pattern modification.
Keywords:
stress granules
; G3BP1
; G3BP2
; Caprin-1
; USP10
; TIA1
; TIAR
; cancer prognosis
; biomarker
; metastasis
; resistance
; cell death
; pro-survival properties
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