Submitted:
15 January 2020
Posted:
17 January 2020
Read the latest preprint version here
Abstract
Stress Granule formation is a pro-survival mechanism helping cells to cope with environmental challenges. Stress Granules have been studied for two decades in fundamental research, and are now being examined in the context of human pathogenesis. Here we review studies highlighting stress granules’ involvement in cancer development through translational pattern modification.
Keywords:
cancer
; metastasis
; stress granules
; G3BP1
; G3BP2
; TIA-1
; TIAR
; CAPRIN-1
; USP10
; prognostic markers
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