Working Paper Review Version 1 This version is not peer-reviewed

Revisiting the Stress Concept for A Better Recipe of Patient Prognostic: Implication of Stress Granule Markers

Version 1 : Received: 15 January 2020 / Approved: 17 January 2020 / Online: 17 January 2020 (08:32:50 CET)
Version 2 : Received: 6 April 2020 / Approved: 7 April 2020 / Online: 7 April 2020 (01:56:12 CEST)

How to cite: Aulas, A.; Finetti, P.; Lyons, S.; Bertucci, F.; Birnbaum, D.; Acquaviva, C.; Mamessier, E. Revisiting the Stress Concept for A Better Recipe of Patient Prognostic: Implication of Stress Granule Markers. Preprints 2020, 2020010180 Aulas, A.; Finetti, P.; Lyons, S.; Bertucci, F.; Birnbaum, D.; Acquaviva, C.; Mamessier, E. Revisiting the Stress Concept for A Better Recipe of Patient Prognostic: Implication of Stress Granule Markers. Preprints 2020, 2020010180

Abstract

Stress Granule formation is a pro-survival mechanism helping cells to cope with environmental challenges. Stress Granules have been studied for two decades in fundamental research, and are now being examined in the context of human pathogenesis. Here we review studies highlighting stress granules’ involvement in cancer development through translational pattern modification.

Subject Areas

cancer; metastasis; stress granules; G3BP1; G3BP2; TIA-1; TIAR; CAPRIN-1; USP10; prognostic markers

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