Elaeocarpus ganitrus Assisted Hydrothermal Synthesis of Gold Nanoparticles: Application to Antibacterial, Antioxidant and Anticancer Activities

Vinay S P; Udayabhanu Udayabhanu; Nagaraju G; Chandrasekhar N

Working Paper Article Version 1 This version is not peer-reviewed

Version 1 : Received: 24 December 2019 / Approved: 25 December 2019 / Online: 25 December 2019 (10:32:12 CET)

In the present study, we have followed the hydrothermal path for the synthesis of gold nanoparticles (Au NPs) from the biomaterial Elaeocarpus ganitrus seeds extract, which is a rapid, eco-friendly, non-chemical way. The prepared NPs were thoroughly analyzed by PXRD & HR-TEM studies and also tested for photocatalytic dye degradation and anticancer studies. Besides, antioxidant, antibacterial and anticancer properties of Au NPs were studied. In vitro studies revealed the dose-dependent cytotoxic effect of Au NPs. The prepared nanoparticles showed good cytotoxic impact against Prostate cancer (PC-3) cells line. The results of the present study could contribute to synthesize new and cost-effective drugs from Elaeocarpus ganitrus seeds extract by using bio approach.

Elaeocarpus ganitrus; Hydrothermal synthesis; Gold nanoparticles; Prostate cancer; Cancer nanomedicine

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Elaeocarpus ganitrus Assisted Hydrothermal Synthesis of Gold Nanoparticles: Application to Antibacterial, Antioxidant and Anticancer Activities

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