Working Paper Article Version 1 This version is not peer-reviewed

Elaeocarpus ganitrus Assisted Hydrothermal Synthesis of Gold Nanoparticles: Application to Antibacterial, Antioxidant and Anticancer Activities

Version 1 : Received: 24 December 2019 / Approved: 25 December 2019 / Online: 25 December 2019 (10:32:12 CET)

How to cite: S P, V.; Udayabhanu, U.; G, N.; N, C. Elaeocarpus ganitrus Assisted Hydrothermal Synthesis of Gold Nanoparticles: Application to Antibacterial, Antioxidant and Anticancer Activities. Preprints 2019, 2019120345 S P, V.; Udayabhanu, U.; G, N.; N, C. Elaeocarpus ganitrus Assisted Hydrothermal Synthesis of Gold Nanoparticles: Application to Antibacterial, Antioxidant and Anticancer Activities. Preprints 2019, 2019120345

Abstract

In the present study, we have followed the hydrothermal path for the synthesis of gold nanoparticles (Au NPs) from the biomaterial Elaeocarpus ganitrus seeds extract, which is a rapid, eco-friendly, non-chemical way. The prepared NPs were thoroughly analyzed by PXRD & HR-TEM studies and also tested for photocatalytic dye degradation and anticancer studies. Besides, antioxidant, antibacterial and anticancer properties of Au NPs were studied. In vitro studies revealed the dose-dependent cytotoxic effect of Au NPs. The prepared nanoparticles showed good cytotoxic impact against Prostate cancer (PC-3) cells line. The results of the present study could contribute to synthesize new and cost-effective drugs from Elaeocarpus ganitrus seeds extract by using bio approach.

Subject Areas

Elaeocarpus ganitrus; Hydrothermal synthesis; Gold nanoparticles; Prostate cancer; Cancer nanomedicine

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