Preprint Article Version 1 This version is not peer-reviewed

Synthesis of Novel Biologically Active Thiazole Dyes and Their Applications

Version 1 : Received: 24 October 2018 / Approved: 2 November 2018 / Online: 2 November 2018 (04:28:50 CET)

How to cite: Abu-Melha, S. Synthesis of Novel Biologically Active Thiazole Dyes and Their Applications. Preprints 2018, 2018110011 (doi: 10.20944/preprints201811.0011.v1). Abu-Melha, S. Synthesis of Novel Biologically Active Thiazole Dyes and Their Applications. Preprints 2018, 2018110011 (doi: 10.20944/preprints201811.0011.v1).

Abstract

This work is aiming to motivation on the prospect of evolving new thiazole dyes with respectable application properties, expected pharmacological activities. Curcumin Coupling with diverse diazonium salts of 2-amino thiazole derivatives as 2-aminobenzothiazole, 2- amino-5-phenylthiazole, 2 amino-5-methylthiazole and 2 amino-5-nitrothiazole to produce novel azo dyes. All synthesised dyes were completely confirmed their structures via elemental and spectroscopic techniques. The synthesised thiazole derivatives were examined for their “antimicrobial, anticancer and antioxidant” activities. All of the synthesized dyes were applied on synthetic fabrics as polyester and successively their dyeing properties, “light, washing, perspiration, rubbing and sublimation” fastness were evaluated. Prepared dyestuffs are suitable for dyeing polyester fabrics. It was initiate that all of prepared dyes own extraordinary colour hue, along with respectable fastness properties. Also the synthesised thiazole derivatives display moral pharmacology activity.

Subject Areas

thiazolyl dyes; anticancer; antioxidant; colour assessment

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