Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Synthesis of Silver Nanoparticles from Anagalis arvensis and Their Biomedical Applications

Version 1 : Received: 15 September 2018 / Approved: 16 September 2018 / Online: 16 September 2018 (10:02:14 CEST)

How to cite: Shah, M.; Anwar, N.; Saleem, S.; Munir, I.; Shah, N.A.; Fida, B.; Khan, A.; Hussain, A.; Amin, F.U. Synthesis of Silver Nanoparticles from Anagalis arvensis and Their Biomedical Applications. Preprints 2018, 2018090282. https://doi.org/10.20944/preprints201809.0282.v1 Shah, M.; Anwar, N.; Saleem, S.; Munir, I.; Shah, N.A.; Fida, B.; Khan, A.; Hussain, A.; Amin, F.U. Synthesis of Silver Nanoparticles from Anagalis arvensis and Their Biomedical Applications. Preprints 2018, 2018090282. https://doi.org/10.20944/preprints201809.0282.v1

Abstract

Background. Nanotechnology is promising field for generating new applications. A green synthesis of nanoparticles through biological methods using plant extract have a reliable and ecofriendly approach to improve our global environment. Methods. Silver nanoparticles (AgNPs) were synthesized using aqueous extract of Anagalis arvensis L and silver nitrate and were physicochemically characterized. Results. The stability of AgNPs toward acidity, alkalinity, salinity and temperature showed that they remained stable at room temperature for more than two months. The SEM and TEM analysis of the AgNPs showed that they have a uniform spherical shape with an average size in the range of 40–78 nm. Further 1-Dibhenyl-2-Picrylhydrazl radical in Anagalis arvensis L.mediated AgNPs showed a maximum activity of 98% at concentration of 200μg/mL. Hydrogen peroxide scavenging assay in Anagalis arvensis L. mediated AgNPs showed a maximum activity of 85% at concentration of 200μg/mL. Reducing power of Anagalis arvensis L.Ag NPs exhibited a higher activity of 330 μg/mL at concentration of 200 μg/mL. These NPs have cytotoxic effects against brine shrimp (Artemia salina) nauplii with a value of 53% LD 178.04μg/mL. Conclusion. The AgNPs synthesized using Anagalis arvensis L. extract demonstrate a broad range of applications.

Keywords

silver nanoparticles; green synthesis; anti diabetic; cytotoxic

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

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