Preprint Article Version 1 This version is not peer-reviewed

Continuous High-Flow System to Trap and Separate Magnetic Particles from Liquid Mixtures

Version 1 : Received: 9 July 2018 / Approved: 10 July 2018 / Online: 10 July 2018 (10:53:45 CEST)

How to cite: Banis, G.; Kouli, M.E.; Hristoforou, E.; Ferraro, A. Continuous High-Flow System to Trap and Separate Magnetic Particles from Liquid Mixtures. Preprints 2018, 2018070167 (doi: 10.20944/preprints201807.0167.v1). Banis, G.; Kouli, M.E.; Hristoforou, E.; Ferraro, A. Continuous High-Flow System to Trap and Separate Magnetic Particles from Liquid Mixtures. Preprints 2018, 2018070167 (doi: 10.20944/preprints201807.0167.v1).

Abstract

Bio-separation of natural molecules as well as clinical compounds has been constantly developed in last decades. Several techniques are available but the majority of them presents drawbacks such us impossibility to be applied for industrial purposes. The main limitations for the scaling up are high costs and the fact that the devices work with microfluid dynamics. Nevertheless, magnetic bio-separation is considered the most prone to be used for large scale applications. Herein, we propose a simple magnetic separation method that is not based on microfluid dynamics, can work in a continuous- and high-flow rate and can be easily automated in order to be used for standard separation purposes. It is based on the use of an anisotropic flexible ferric magnetic strip, Teflon hoses and a pumping device. We show the modelling of the separation process along with an experimental test on iron oxide magnetic particles. The results showed that it is possible to remove, and separately collect, more than 92% of magnetic particles from a liquid solution of 100 ml in roughly 15 minutes.

Subject Areas

Bio-separation, magnetic separation, magnetic particles, continuous-flow

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.