Submitted:
12 June 2018
Posted:
13 June 2018
You are already at the latest version
Abstract
Retinoid X receptor (RXR) antagonists are not only useful as chemical tools for biological research, but also are candidate drugs for treatment of various diseases, including diabetes and allergy, although no RXR antagonist has yet been approved for clinical use. In this review, we describe currently available RXR antagonists, their structural classification, and their evaluation, focusing on the latest research.
Keywords:
Retinoid X receptor
; RXR
; antagonists
; structural classification
; heterodimers
; permissive
; tRXR
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