Version 1
: Received: 28 April 2017 / Approved: 2 May 2017 / Online: 2 May 2017 (17:20:34 CEST)
How to cite:
Dametto, J.F.D.S.; Lira, L.Q.D.; Melo, L.R.M.; Damasceno, M.M.; Silva, N.L.D.N.; Dimenstein, R. Maternal Supplementation with RRR-α-Tocopherol (400 IU) and Its Relationship with Serum and Breast Milk Retinol. Preprints2017, 2017050024. https://doi.org/10.20944/preprints201705.0024.v1
Dametto, J.F.D.S.; Lira, L.Q.D.; Melo, L.R.M.; Damasceno, M.M.; Silva, N.L.D.N.; Dimenstein, R. Maternal Supplementation with RRR-α-Tocopherol (400 IU) and Its Relationship with Serum and Breast Milk Retinol. Preprints 2017, 2017050024. https://doi.org/10.20944/preprints201705.0024.v1
Dametto, J.F.D.S.; Lira, L.Q.D.; Melo, L.R.M.; Damasceno, M.M.; Silva, N.L.D.N.; Dimenstein, R. Maternal Supplementation with RRR-α-Tocopherol (400 IU) and Its Relationship with Serum and Breast Milk Retinol. Preprints2017, 2017050024. https://doi.org/10.20944/preprints201705.0024.v1
APA Style
Dametto, J.F.D.S., Lira, L.Q.D., Melo, L.R.M., Damasceno, M.M., Silva, N.L.D.N., & Dimenstein, R. (2017). Maternal Supplementation with <em>RRR</em>-α-Tocopherol (400 IU) and Its Relationship with Serum and Breast Milk Retinol. Preprints. https://doi.org/10.20944/preprints201705.0024.v1
Chicago/Turabian Style
Dametto, J.F.D.S., Nathalia Lorena do Nascimento Silva and Roberto Dimenstein. 2017 "Maternal Supplementation with <em>RRR</em>-α-Tocopherol (400 IU) and Its Relationship with Serum and Breast Milk Retinol" Preprints. https://doi.org/10.20944/preprints201705.0024.v1
Abstract
Vitamin A and E are important during pregnancy, the neonatal period, and childhood. The objective of this study was to assess whether maternal RRR-a-tocopherol supplementation affects serum and breast milk retinol. Serum was collected at baseline and twenty days later, and breast milk, at baseline, and on days 1, 7, and 20 after delivery. After the baseline serum collection, the supplemented group (n=16) received a single 400 IU of RRR-α-tocopherol. The control group (n=18) was only performed collections. Retinol and alpha tocopherol levels were determined by liquid chromatography. Serum retinol and alpha tocopherol at baseline and 20 days after delivery indicated proper vitamin A (> 20 µg/dL) and E (> 516 μg/dL) statuses in the control and supplemented groups (p > 0.05). Colostrum retinol levels on days 1 and 7 after delivery were significantly higher in the supplemented group (p = 0.018 and p = 0.012, respectively). Maternal vitamin E supplementation increased colostrum retinol by 52.23% and 111.2%, 24 hours and 7 days, respectively. However, retinol in mature milk did not differ between the groups (p > 0.05). In conclusion, the supplementation with 400 IU of RRR-α-tocopherol improved vitamin A bioavailability in breast milk.
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
