Search Subject Areas | Preprints.org

Preprint ARTICLE | doi:10.20944/preprints202404.1026.v1

2D Shear Wave Elastography of the Thyroid in Clinically Healthy Dogs of Different Age Groups

Denise J. Ramos, Tamiris Disseli, Diego R. Gomes, Luiz Paulo N. Aires, Stefany T. Tinto, Diana V. V. Salazar, Mariane M. F. Pereira, Brenda S. P. Miranda, Ana Paula L. Oliveira, Bruna B. Lima, Ricardo A. R. Uscategui, Marcus Antônio R. Feliciano

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: dogs; diagnostic imaging; elastography; stiffness; thyroid; ultrasound

Online: 16 April 2024 (10:42:39 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202404.0746.v1

Self-Report Measurement by the Rider to Monitor Their Horses’ Adaptive Response to Training and Competition in Eventing

Insa Rump-Dierig, Katharina Charlotte Jensen, Anna M. Liedtke, Heidrun Gehlen

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: self-report measurement; fatigue; training management; performance diagnostics

Online: 11 April 2024 (12:52:17 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202404.0734.v1

Which factors influence the consumption of antibiotics in Q-fever-positive dairy farms in Northern Germany?

Niclas Huber, Natascha Gundling, Maria Thurow, Uwe Ligges, Martina Hoedemaker

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Coxiella burnetii vaccination antibiotics dairy cows

Online: 10 April 2024 (11:00:35 CEST)

Show abstract| Download PDF| Share

Preprint CASE REPORT | doi:10.20944/preprints202404.0350.v1

Treatment and healing of Leishmaniasis in a Wolf in Semi-captivity Regime from an Educational Center of Zamora Province (Spain)

JAVIER MERINO-GOYENECHEA, JESUS PALACIOS-ALBERTI, TOMAS YANES-MARTÍNEZ, MARÍA MARTÍNEZ-VALLADARES, RAFAEL BALAÑA-FOUCE

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Canine leishmaniasis; Leishmania infantum; wild animals; wolves; semi-captivity

Online: 4 April 2024 (17:32:20 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202404.0018.v1

Select Venous Analytes and Fibrinogen Determination Using Two Methods in Brown Pelicans

Amelia G Gessner-Knepel, Jordan Gentry, Sharon Schmalz, Karen Russell, Jennifer Jill Heatley

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: brown pelican; fibrinogen; chemistry; bloodwork; blood gas

Online: 1 April 2024 (10:13:46 CEST)

Show abstract| Download PDF| Share

Preprint CASE REPORT | doi:10.20944/preprints202403.0752.v1

Ovarian Fibrothecoma in a Mare-Case Report

Raimonda Tamulionytė-Skėrė, Nomeda Juodžiukynienė, Paulina Rimkutė, Renata Gruodytė, Iveta Duliebaitė, Akvilė Savickytė

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: thecoma; ovarian tumor; neoplasia; histopathology

Online: 13 March 2024 (07:24:30 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202403.0709.v1

Effect of Nucleic Acid Analog Administration on Fluctuations of Albumin to Globulin Ratio in Cats with Feline Infectious Peritonitis

Masato Katayama, Yukina Uemura, Daichi Katori

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: cat; feline infectious peritonitis; non-effusive; nucleic acid analog; albumin to globulin ratio; feline coronavirus; routine treatment

Online: 12 March 2024 (14:32:02 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202403.0582.v1

Equine Musculoskeletal Pathologies: Clinical Approaches and Therapeutical Perspectives – A Review

I.L. Reis, B. Lopes, P. Sousa, A.C. Sousa, Ana Rita Caseiro, C.M. Mendonça, J.M. Santos, LM Atayde, R.D. Alvites, Ana Colette Maurício

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Conservative therapies; equine; hemoderivatives; musculoskeletal; osteoarthritis; physiotherapy; regenerative therapies; sports medicine; stem cell; tendinitis

Online: 11 March 2024 (07:04:12 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202403.0464.v1

Review of the Current Status on Livestock Abortigenic Diseases Surveillance in Africa and Asia

George Peter Semango, Joram Buza

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: abortion; livestock; Africa; Asia

Online: 8 March 2024 (04:20:32 CET)

Show abstract| Download PDF| Supplementary Files| Share

Introduction Livestock abortigenic agents, which are microorganisms that lead to premature foetal death and expulsion before completion of the gestation period, are common in Africa and Asia. Abortion events cause economic losses by lowering reproduction (and hence herd/flock sizes) and effects on milk production. Despite the importance of livestock production for food security and livelihoods of millions of the world’s poorest communities, very little is known about the scale, magnitude or causes of livestock abortion in Africa. The aim of this review was to determine the current status of the burden of livestock abortion and surveillance measures adopted for livestock abortigenic pathogens in Africa and Asia, and to explore feasible surveillance technologies. Methodology A systematic literature search was conducted using Preferred Reporting of Systematic Reviews and Meta-analyses (PRISMA) guidelines in four databases for studies published between 1 Jan 1990 and 31 July 2021 that reported epidemiological surveys of livestock abortigenic pathogens in cattle, goats and sheep in Africa and Asia including; Brucella spp., Neospora caninum, Toxoplasma gondii, Rift valley fever virus, Coxiella burnetii, Chlamydia, Leptospira and Bovine viral Diarrhoea Virus. A meta-analysis was used to estimate the species-specific prevalence of the abortigenic diseases and the region where they were detected. Results In the systematic literature search, 48 full papers were included which in total included 50 species-specific surveillance reports from Africa and 19 from Asia. Adjusted median seroprevalence calculations estimated Brucella at 6.85% (range 1.2-11.6) of 9071 sheep, 3.35% (range 0.90-5.40) of 17,007 goats, 8.95% (range 0.50-63.60) of 171,733 cattle, Neospora at 6.80% (range 6.80 -6.80) of 555 sheep, 10.80 (range 10.80-10.80) of 185 goats, 12.65% (range 3.40- 25.60) of 3775 cattle, Toxoplasma at 27.50% (range 1.40 – 75.90) of 2284 sheep, 32.0% (range 20.00- 64.80) of 1226 goats, 7.50% (range 7.50 - 7.50) of 174 cattle, Coxiella at 9.20 (range 9.20 – 9.20) of 184 sheep, 24.20% (range 24.20-24.20) of 91 goats, 13.80% (range 13.80-13.80) of 217 cattle, Rift valley fever virus at 7.70 (2.40-40.00) of 874 sheep, 20.95 (range 2.50-40.00) of 547 goats, 7.45% (range 3.60-11.30) of 309 cattle, Bovine viral diarrhea virus at 78.90 (range 78.90 – 78.90) of 398 cattle, Leptospira at 70.50 (range 70.50 – 70.50) of 373 cattle and Chlamydia at 6.60 (6.60-6.60) of 803 sheep. We found that most studies, 45 (89%) used serological surveys, 1 (2%) used molecular and 1 (2%) reported to have used Mobile-phone based surveillance approach. Three studies (6.25%) of the 48 included were embedded in the national surveillance programs of the respective countries they were conducted, majority 89% were stand-alone cross-sectional studies. Conclusion In conclusion, livestock abortigenic pathogens are still a burden in many African and Asian countries.

Preprint ARTICLE | doi:10.20944/preprints202403.0457.v1

Computational Exploration and Molecular Dynamic Simulation for the Discovery of Antiviral Agents Targeting Newcastle Disease Virus

Iqra Ali, Ihtisham Ul Haq, Nimra Imtiaz, Muhammad Nasir Iqbal, Rafi ur Rahman, Wadi B. Alonazi, Muhammad Asif Rasheed

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Newcastle disease virus; natural compounds; antiviral drugs; NDV; MD simulation; Hemagglutinin Neuraminidase; biological activity; ADMET; pharmacophore; screening

Online: 8 March 2024 (03:56:28 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202403.0182.v1

Anemia in Dogs with Acute Kidney Injury

Ilaria Lippi, Francesca Perondi, Giulia Ghiselli, Sara Santini, Verena Habermaass, Veronica Marchetti

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: anemia; AKI; dog; IRIS grade

Online: 4 March 2024 (15:32:33 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202402.1006.v1

Estrus Cycle, Pyometra, and Insulin-Resistant Diabetes in the Bitch: What is Known and Why it is Relevant?

Álan Gomes Pöppl, José Lucas Xavier Lopes, Taís Bock Nogueira, Denise Iparraguirre Da Silva, Bruna dos Santos Machado

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: diestrus; progesterone; growth hormone; insulin resistance; insulin receptor; spaying; aglepristone; dog

Online: 19 February 2024 (08:03:13 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202402.0735.v1

Early Intensive Neurorehabilitation in Traumatic Peripheral Nerve Injury – State of the Art

Débora Gouveia, Ana Cardoso, Carla Carvalho, Ana Catarina Oliveira, António Almeida, Óscar Gamboa, B. Lopes, André Coelho, R.D. Alvites, Artur Severo P. Varejão, Ana Colette Maurício, António Ferreira, Ângela Martins

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: PNI; neurorehabilitation; nerve repair; electrical stimulation; exercises; locomotor training.

Online: 13 February 2024 (10:27:28 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202402.0508.v1

Ovariectomy in Mouflons in Field Condition: Comparative Assessment of Midventral and Flank Laparotomy Approaches

Lorenza Frattina, Alice Carbonari, Matteo Burgio, Francesca Giannini, Francesco Locantore, Annalisa Rizzo, Vincenzo Cicirelli

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: mouflon; ovariectomy in field; field oocyte collection; midventral and flank approaches; anesthesia in filed

Online: 8 February 2024 (14:23:56 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202402.0315.v1

Overview of Cyanide Poisoning in Cattle from Sorghum halepense and S. bicolor Cultivars in North-West Italy

Stefano Giantin, Alberico Franzin, Fulvio Brușa, Vittoria Montemurro, Elena Bozzetta, Elisabetta Caprai, Giorgio Fedrizzi, Flavia Girolami, Carlo Nebbia

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Sorghum bicolor; Sorghum halepense; dhurrin; cyanide poisoning; cattle; drought

Online: 6 February 2024 (09:19:48 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202401.2009.v1

Rapid Antibacterial Activity Assessment of Chimeric Lysin

Jin-Mi Park, Jun-Hyun Kim, Gun Kim, Hun-Ju Sim, Sun-Min Ahn, Kang-Seuk Choi, Hyuk-Joon Kwon

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Staphylococcus aureus; chimeric lysins; cell-free expression system; linker optimization; SH3 shuffling; antibacterial activity ranking

Online: 29 January 2024 (13:07:53 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202401.2011.v1

Ultrasound and Elastosonographic Features of the Patellar Ligament in Dogs Affected by Cranial Cruciate Ligament Rupture

Pennasilico Luca, Antonella Volta, Sara Sassaroli, Caterina Di Bella, Valentina Riccio, Nicola Pilati, Adolfo Maria Tambella, Fabrizio Dini, Angela Palumbo Piccionello

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: elastosonography; patellar ligament; stifle; cranial cruciate ligament; dog

Online: 29 January 2024 (09:26:10 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202401.1915.v1

Equine Metacarpophalangeal Joint Partial and Full Thickness Defects Treated with Allogenic Equine Synovial Membrane Mesenchymal Stem/Stromal Cell and Umbilical Cord Mesenchymal Stem/Stromal Cell Conditioned Medium: The Proof-of-Concept

I.L. Reis, B. Lopes, P. Sousa, A.C. Sousa, Ana Rita Caseiro, I. Briote, Ana Matilde Rocha, J.P. Pereira, C.M. Mendonça, J.M. Santos, Luís Lamas, L.M. Atayde, R.D. Alvites, Ana Colette Maurício

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Equine; mesenchymal stem/stromal cells; synovial membrane mesenchymal stem cell; umbilical cord conditioned medium; clinical case; cartilage; subchondral bone; osteoarthritis; allogeneic cell-based therapies; horses.

Online: 26 January 2024 (13:56:06 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202401.1229.v1

True Diaphragmatic Hernia (Morgagni Hernia) Incidentally Diagnosed with Positive Contrast Peritoneography in a Cat: A Rare Case Report and a Review

Jack-Yves Deschamps, Théo Corbarieu, Nour Abboud, Françoise A. Roux

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: true diaphragmatic hernia; diaphragmatic hernia; Morgagni hernia; peritoneography; incidentalloma; cat

Online: 16 January 2024 (12:28:40 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202401.0832.v1

Seroprevalence of Anti-SARS-CoV-2 Antibodies in Cats during Five Waves of COVID-19 Epidemic in Thailand and Correlation with Human Outbreaks

Suporn Thongyuan, Jeeraphong Thanongsaksrikul, Potjanee Srimanote, Wallaya Phongphaew, Piyaporn Eiamcharoen, Naris Thengchaisri, Angela Bosco-Lauth, Nicola Decaro, Rungrueang Yodsheewan

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: COVID-19; SARS-CoV-2; indirect ELISA; surrogate viral neutralization assay; seroprevalence; correlation; Thai; cat

Online: 10 January 2024 (12:03:28 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202401.0539.v1

A Multidimensional Evaluation of the Factors in the Animal Welfare Assessment Grid (AWAG) That Are Associated and Predictive of Behaviour Disorders in Dogs

Rachel Malkani, Sharmini Julita Paramasivam, Sarah Wolfensohn

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Dog welfare, Dog behaviour, Welfare assessment, Dog welfare, AWAG

Online: 8 January 2024 (10:08:42 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202401.0036.v1

Painless Artificial Intelligence Point-of-Care hemogram diagnosis in Companion Animals

Teresa Guerra Barroso, Joana Maria Costa, António Hugo Gregório, Rui Costa Martins

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Point-of-care; Spectroscopy; Dog, Hemogram; Diagnosis; Painless; Reagentless; Ani- 38 mal Welfare; Artificial Intelligence.

Online: 3 January 2024 (03:51:42 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.2348.v1

Respiratory Effects of Continuous Positive Airway Pressure Administered during Recovery from General Anesthesia in Brachycephalic Dogs

Caterina Vicenti, Pablo E Otero, Angela Briganti, Vincenzo Rondelli, Marzia Stabile, Claudia Piemontese, Antonio Crovace, Luca Lacitignola, Francesco Staffieri

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Brachycephalic; dog; CPAP; oxygenation; anesthesia ;

Online: 30 December 2023 (16:13:16 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.2044.v1

Randomized Clinical Trial Comparing Itraconazole and the Combination Therapy with Itraconazole and Potassium Iodide for the Treatment of Feline Sporotrichosis

Erica Guerino dos Reis, Sandro Antonio Pereira, Luisa Helena Monteiro De Miranda, Raquel V. C. Oliveira, Marcel de Souza Borges Quintana, Paula Gonçalves Viana, Anna Barreto Fernandes Figueiredo, Cindy Caroline dos Santos Honorato, Gabriela Reis Pereira-Oliveira, Jessica Nunes Silva, Tânia Pacheco Schubach, Isabella Dib Ferreira Gremião

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: sporotrichosis; Sporothrix; cats; itraconazole; potassium iodide; treatment; combination therapy

Online: 27 December 2023 (09:45:46 CET)

Show abstract| Download PDF| Share

Preprint COMMUNICATION | doi:10.20944/preprints202312.1872.v1

Pharmacokinetic and Pharmacodynamic Analysis Using Monte Carlo Simulation of the Oxacephem Antibiotic Flomoxef against Extended-Spectrum β-Lactamase-Producing Enterobacterales from Dogs

Mizuki Kusumoto, Makoto Jitsuiki, Tomoki Motegi, Kazuki Harada

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: pharmacokinetics–pharmacodynamics approach; flomoxef; extended-spectrum β-lactamases; Enterobacterales; Dogs

Online: 26 December 2023 (02:37:19 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1400.v1

Understanding the Bactericidal and Virucidal Capacity of Potassium Peroxymonosulfate in Varied Environments and Its Utilization in Eradicating Germs on Diverse Surfaces and Clothing

Darsaniya Punyadarsaniya, Nutnaree Kunanusont, Kazuaki Takehara, And Sakchai Ruenphet

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: bactericidal; carrier surface; cloth; disinfectant; potassium peroxymonosulfate; virucidal

Online: 19 December 2023 (07:12:34 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1323.v1

Pharmacokinetics of Tilmicosin in Plasma, Urine and Feces after a Single Intragastric Administration in Donkey (Equus asinus)

Bowen Yang, Shijie Liu, Yanxin Guo, Honglei Qu, Yulong Feng, Yantao Wang, Boying Dong, Yanjie Dong, Shancang Zhao, Shimeng Huang, Lihong Zhao, Jianyun Zhang, Cheng Ji, Qiugang Ma

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: tilmicosin; pharmacokinetics; intragastric administration; excretion; donkey

Online: 18 December 2023 (10:52:55 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1295.v1

Assessing the precision of point-of-care immunological analyzer for swift progesterone measurement and guidance for determining the optimal breeding time in bitches

Thanikran Suwannachote, Supphathat Wutthiwitthayaphong, Saengtawan Arayatham, Wisut Prasitsuwan, Sakchai Ruenphet

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: bitches; chemiluminescent microparticle immunoassay; optimal breeding time; point-of-care analyzer; serum progesterone

Online: 18 December 2023 (10:28:33 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1116.v1

Changes in the Serum Metabolome in an Inflammatory Model of Osteoarthritis in Rats

Neus I. Berenguer, Vicente J. Sifre Canet, Carme Soler Canet, Sergi Segarra, Alejandra García de Carellán, C. Iván Serra Aguado

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: osteoarthritis (OA); metabolomics; liquid chromatography/mass spectrometry (LC/MS); metabolic pathway; lipid molecules.

Online: 15 December 2023 (03:43:14 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.0006.v1

Transitional and/or Supernumerary Vertebra in Lumbosacrocaudal Region of the Spine – a Reality in All Domestic Mammals

Costică Toader Covașă

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: transitional vertebra; lumbosacral and sacrocaudal junctions; domestic mammals; comparing morphology

Online: 1 December 2023 (05:02:02 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.0020.v1

Influence of Recombinant Bovine Somatotropin (rbST) on the Metabolic Profile and Milk Composition of Lactating Murrah Buffalo

Marcelo Arne Feckinghaus, Mariana Guimarães de Oliveira Diogo, Vanessa Martins Storillo, Fabio Celidonio Pogliani, Bruno Moura Monteiro, Paulo Fantinato Neto, Melina Marie Yasuoka, Daniela Becker Birgel, Eduardo Harry Birgel Junior

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: bovine somatotropic hormone; rbST; metabolic parameters; milk yield

Online: 1 December 2023 (03:31:35 CET)

Show abstract| Download PDF| Share

The use of recombinant bovine somatotropin (rbST) leads to an increase, in variable amounts, of milk production in buffalo, but there is a lack of information on the influence of rbST on their metabolism. This study looked at the effects of a single 500 mg dose of rbST on lipid profile, liver and kidney function and physical, chemical and cellular constitution of milk in 14 buffalo over 14 days, from the 100th day of lactation, and compared them with 14 animals in a control group. From the 1st day after rbST, there was a rise in beta hydroxybutyrate (β-HBO), possibly due to the higher dry matter intake or by biotransformation of NEFA into β-HBO. Treatment did not influence blood glucose, non-esterified fatty acids (NEFA), triglycerides, cholesterol, total protein, albumin, AST, GGT, bilirubin, urea or creatinine. In 71.3% of the buffalo there was a gradual increase in milk production with maximal response in the first week that was then followed by a gradual decrease, whilst in 21.4%, the increase in production occurred between 7 and 10 days, and only 7.1% of animals did not respond. On the 3rd, 5th, 7th and 10th days after treatment, an increase was found in milk production between the two groups equal to 1.04, 1.52, 1.42 and 1.06 liters, respectively. In relative terms this means an increase in milk production, respectively, of 15.1%; 21.0%; 19.8 % and 15.1 %. The constitution of the milk showed no difference in the amounts of fat, lactose, total solids or somatic cell count; however, on the 3rd day after rbST, there was a decrease in protein; notably, from the 5th day, protein values show no statistical difference. It can be concluded that the application of rbST in buffalo from the 100th day of lactation is metabolically safe, since the treatment neither caused imbalances in fat metabolism nor overloaded the liver or renal function, and the changes in milk composition were transient and limited to a decrease in milk protein.

Preprint REVIEW | doi:10.20944/preprints202311.1825.v1

Use of New Ultrasonography Methods for Detecting Neoplasms in Dogs and Cats: A Review

Anna Carolina Mazeto Ercolin, Alex Silveira Uchoa, Luiz Paulo Nogueira Aires, Diego Rodrigues Gomes, Stefany Tagliatela Tinto, Giovanna Serpa Maciel Feliciano, Marcus Antônio Rossi Feliciano

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Elastography; Contrast-enhanced Ultrasound; Neoplasia; Metastasis; Feline; Canine

Online: 29 November 2023 (09:44:47 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.1604.v1

Ehrlichia canis and Rickettsia conorii Infections in Shelter Dogs: Seropositivity and Implications for Public Health

Paulo Afonso, Ana Patrícia Lopes, Hélder Quintas, Luís Cardoso, Ana Cláudia Coelho

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Antibodies; dog; Ehrlichia canis; Portugal; Rickettsia conorii; shelter

Online: 27 November 2023 (03:11:44 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.1487.v1

Comprehensive Histopathological and Immunohistochemical Evaluation of African Swine Fever in Romanian Swine: Insights into Pathogenesis and Diagnostic Strategies

Andrei Ungur, Andras-Laszlo Nagy, Cornel Cătoi

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: African Swine Fever; Histopathology; Immunohistochemistry; Tissue-specific prevalence

Online: 23 November 2023 (08:42:00 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.1453.v1

Treatment of Equine Tarsus Long Medial Collateral Ligament Desmitis with Allogenic Synovial Membrane Mesenchymal Stem/Stromal Cells Enhanced by Umbilical Cord Mesenchymal Stem/Stromal Cell-Derived Conditioned Medium: Proof of Concept

Inês Leal Reis, Bruna Lopes, Patrícia Sousa, Ana Catarina Sousa, Mariana Branquinho, Ana Rita Caseiro, Alexandra Rêma, Inês Briote, Carla Mendonça, Jorge Miguel Santos, Luís Atayde, Rui Alvites, Ana Colette Maurício

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Allogenic; Case study; Ligament; Mesenchymal stem cells; MSC-based therapies; Secretome; Sport horses; Synovial membrane mesenchymal stem cell; Umbilical cord conditioned medium

Online: 23 November 2023 (04:58:38 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.1423.v1

Antitumor Effect of Novel Berberine Analogues in a Canine Mammary Tumor Cell Line and in Zebrafish Reporters via Wnt/β-Catenin and Hippo Pathways

Alessandro Sammarco, Giorgia Beffagna, Roberta Sacchetto, Andrea Vettori, Federico Bonsembiante, Giulia Scarin, Maria Elena Gelain, Laura Cavicchioli, Silvia Ferro, Cristina Geroni, Paolo Lombardi, Valentina Zappulli

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: berberine derivates; dog; mammary tumors; zebrafish; Hippo; Wnt; β-catenin

Online: 22 November 2023 (11:45:04 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint COMMUNICATION | doi:10.20944/preprints202311.1042.v3

Effect of Specific Probiotic Mixture on Coronavirus (FeCoV) Viral Load in 25 Naturally-Infected, Clinically Healthy, Purebred Birmanian Cats

Sara Mangiaterra, Matteo Cerquetella, Alessandra Gavazza, Maria Elena Turba, Sara Berardi, Lucia Biagini, Giacomo Rossi

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: FeCov; cat; Birmanian; probiotic; fecal viral-load

Online: 20 November 2023 (05:37:53 CET)

Show abstract| Download PDF| Share

Preprint COMMUNICATION | doi:10.20944/preprints202311.1042.v2

Effect of Specific Probiotic Mixture on Coronavirus (FeCoV) Viral Load in 25 Naturally-Infected, Clinically Healthy, Purebred Birmanian Cats

Sara Mangiaterra, Matteo Cerquetella, Alessandra Gavazza, Maria Elena Turba, Sara Berardi, Lucia Biagini, Giacomo Rossi

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: FeCov; cat; Birmanian; probiotic; fecal viral-load

Online: 17 November 2023 (04:38:13 CET)

Show abstract| Download PDF| Share

Preprint COMMUNICATION | doi:10.20944/preprints202311.1042.v1

Effect of Specific Probiotic Mixture on Coronavirus (FeCoV) Viral Load in 25 Naturally-Infected, Clinically Healthy, Purebred Birmanian Cats

Sara Mangiaterra, Matteo Cerquetella, Alessandra Gavazza, Maria Elena Turba, Sara Berardi, Lucia Biagini, Giacomo Rossi

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: FeCov; cat; Birmanian; probiotic; fecal viral-load

Online: 16 November 2023 (02:58:30 CET)

Show abstract| Download PDF| Share

Preprint BRIEF REPORT | doi:10.20944/preprints202311.0641.v1

The Immunogenicity of a Foot-and-Mouth Disease Virus Serotype O Vaccine in Commercial and Subsistence Cattle Herds in Zambia

Frank Banda, Anna B Ludi, Ginette Wilsden, Clare Browning, Lynnfield Mooya, Masuzyo Ngoma, Geoffrey M Muuka, Cornelius Mundia, Paul Fandamu, Henry L Kangwa, David J Paton, Donald P King, Melvyn Quan

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: foot-and-mouth disease; immunogenicity; vaccine; field evaluation

Online: 9 November 2023 (13:35:29 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202311.0158.v1

Establishing Reference Intervals of Whole Blood Viscosity and its Correlation with Hematology and Serum Chemistry in Cats using Scanning Capillary Method

Chae-Yeong Lee, Sung-Lim Lee, Eunju Kim, Jinsu Kang, Sunjun Jung, Namsoo Kim, Jinmu Jung, Dong Hwan Lee, Yoon-Ho Roh, Dongbin Lee

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: whole blood viscosity; reference interval; shear rate; scanning capillary tube viscometer; cat

Online: 3 November 2023 (03:31:23 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202310.2099.v1

Live-Attenuated Salmonella-Based Oral Vaccine Candidates Expressing PCV2d Cap and Rep by Novel Expression Plasmids as a Vaccination Strategy for Mucosal and Systemic Immune Responses against PCV2d

Khristine Kaith Sison Lloren, Chandran Sivasankar, John Hwa Lee

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Oral vaccine; Salmonella delivery; porcine circovirus type 2; PCV2d

Online: 31 October 2023 (14:35:37 CET)

Show abstract| Download PDF| Share

Preprint CASE REPORT | doi:10.20944/preprints202310.1595.v1

Rare Cranial Osteopathy in a Northern Bottlenose Whale (Hyperoodon ampullatus) Stranded in Rhode Island, Northwest Atlantic, in the 19^thCentury

Jennifer Anné, Marie-Francoise Van Bressem, Koen Van Waerebeek

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: pterygoid malformation; exostosis; osteoma; beaked whales; North Atlantic; bone disease

Online: 25 October 2023 (07:59:30 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202310.0265.v1

Action of Viscus Album L. on Diabetes and Hypertension in the Veterinary Field

Paolo Pelini

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Viscum album; Paolo Pelini; veterinary medicine; hypertension,diabetes

Online: 5 October 2023 (08:27:01 CEST)

Show abstract| Download PDF| Share

Viscum album L., also known as “Mistletoe”, is a hemiparasitic plant native to the European continent that grows on various host trees. This plant contains a wide variety of active compounds that can be used for treat various diseases, such as diabetes, hypertension, as an anti- inflammatory and antioxidant. However, it is most indicated in human medicine for the adjuvant treatment of cancer patients. Both for its properties directed against neoplastic cells and for its antioxidant and anti-inflammatory properties. In Veterinary Medicine, I am very few studies are recorded for animals, although formulations are available for commercial use in oral and injectable form, mostly for homeopathic use. Many studies have been conducted on a large scale by groups of independent researchers and doctors in several countries, such as Switzerland, Germany and Brazil. Therefore, this review aimed to collect data on the use of Viscum album in Veterinary Medicine in order to encourage research in this sector not only in oncological diseases but in other directions in which Viscum can find use as an anti-pretensive and anti-diabetic agent. Introduction: Lectins, flavonoids, phenols such as phenylpropanoids, coumarins, sterols, lignans, terpenoids, phenylpropanoids, alkaloids, fatty acids and viscotoxins are among the main active ingredients present in the phytocomplexes of the Viscum album plant. In particular, Attention should be given to specific oligoproteins in consideration of their activity biological [1]. present in The foliage and fruits of V. album, as in other related species, contain low-weight proteins molecular type of thionin, called viscotoxins, as well as characteristic lectins, called viscolectins, both can contribute to its system defense and can be found in extracts and related products. These classes of Viscum microproteins have received considerable attention due to their contribution to effects cytotoxics and immunostimulants of mistletoe extracts used in medicine, as discussed later, including their mechanism of action [ 2–3] viscotoxins can increase the number of cells circulating naturalkillers and consequently improve the response host antitumor immunity [ 8]. Likewise, the a viscotoxin has an effective immunomodulatory impact on human and animal granulocytes [ 9, 10] and also acts on cellular apoptosis [11]. The cytotoxic action of viscotoxin is comparable to that of conventional chemotherapeutic agents [ 12].

Preprint CASE REPORT | doi:10.20944/preprints202309.1911.v1

Treatment of Three Ferrets Diagnosed with Ferret Systemic Coronaviral Disease Using the Nucleoside Analogue GS-441524

Federica Scaletti, Julia Puffal, Amanda J. Neece

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: antiviral; coronavirus; ferrets; FSCD; FIP

Online: 28 September 2023 (03:19:13 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202309.1398.v1

Involvement of Epithelial to Mesenchymal Transition in Canine Mammary Tumor Progression

Madalina Luciana Gherman, Oana Zanoaga, Liviuta Budisan, Lajos Raduly, Ioana Berindan-Neagoe

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: cancer; canine; mammary tumors; epithelial to mesenchymal transitionว doxorubicin

Online: 22 September 2023 (06:33:35 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202309.1414.v1

Arthroscopic Management of Joint Problems in the Sport Horse

Antonio Manuel Cruz, Michael Roecken

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Arthroscopy; Joint disease; Surgery; Sport horses

Online: 20 September 2023 (13:06:07 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202309.1227.v1

Pig Sedation and Anesthesia for Medical Research

Ruxandra Costea, Ioana Ene, Ruxandra Pavel

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: sedation; anesthesia; pig; research models, protocols

Online: 19 September 2023 (08:26:35 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202309.0891.v1

Susceptibility Trends of Respiratory and Enteric Porcine Pathogens to Last Resource Antimicrobials

Anna Vilaro, Elena Novell, Vicens Enrique-Tarancon, Jordi Baliellas, Lourdes Migura-Garcia, Lorenzo Fraile

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: trend analysis; antimicrobial susceptibility; porcine pathogens

Online: 14 September 2023 (03:40:35 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202309.0650.v1

Lyssavirus Presence in the Brain of Suspected Rabid, Vaccinated and Unvaccinated Dogs: Implications for Rabies Control in Ghana

Odoom Theophilus, Daniel Arthur, Richard Kwamena Abbiw, Sherry Ama Mawuko Johnson, Patrick Tetteh Ababio, Daniel Baah, William Tasiame, Benjamin Emikpe, Gabriel Bright Dzotefe

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: rabies; ghana; dog vaccination; lyssavirus

Online: 11 September 2023 (10:39:07 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202309.0559.v1

Optimization of RT-QuIC Assay Duration for Screening Chronic Wasting Disease in White-Tailed Deer

Gokhan Yilmaz, Tamara Morrill, Cian Ward, Gordon Mitchell, Andrei Soutyrine, Hanhong Dan, Min Lin, Jiewen Guan

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: RT-QuIC; Chronic Wasting Disease; Diagnostics; Optimization

Online: 7 September 2023 (15:45:02 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202309.0403.v1

Phase-Dependent Differential In Vitro and Ex Vivo Susceptibility of Aspergillus flavus and Fusarium keratoplasticum to Azole Antifungals

Darby Roberts, Jacklyn Salmon, Marc A Cubeta, Brian C Gilger

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Aspergillus; Fusarium; fungal keratitis; antifungal susceptibility; MIC; azole

Online: 6 September 2023 (10:33:53 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202309.0095.v1

Effect of Injectable or Oral Trace Mineral Supplementation on Beef Calf Health Status and Growth

Nicolas Herman, Agnès Batard, Sébastien Geollot, Thibault Devambez, Luc Durel

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Beef calf; Trace mineral supplementation; Passive transfer; Innate immunity; Adaptive immunity; Health status

Online: 1 September 2023 (17:02:37 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.1725.v1

The Use of Bits in Equestrian Sports and Its Implications for Equine Welfare

Julia Schacht, Anna May, Heidrun Gehlen

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: equestrian sport; welfare; bit use; equine behavior; behavioral effects; horse satisfaction; horses; bits

Online: 24 August 2023 (07:59:33 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.0934.v1

Efficacy of a Pharmaceutically Alginate-Coated Phytoremedy (Black Garlic and Turmeric) for the Control of Natural Coccidia Infestation in Turkeys

Yazmin Alcala, Hector Sumano, Lilia Gutierrez

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: alginate; turmeric; garlic; turkeys; Eimeria

Online: 11 August 2023 (11:03:05 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.0654.v1

Cardiovascular and Respiratory Effects of Increased Intra-abdominal Pressure with and without Dexmedetomidine in Anesthetized Dogs

Dongseok Kim, Minjun Seo, Geonho Choi, Sungin Lee, Sang-Kwon Lee, Won-Jae Lee, Sung-Ho Yun, Young-Sam Kwon, Min Jang

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: dog; intra-abdominal pressure; dexmedetomidine; hypercapnia; PulseCO

Online: 9 August 2023 (03:13:15 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.0455.v1

Development and Validation of a Canine Health Related QoL Questionnaire and a Human-Canine Bond Questionnaire for Use in Veterinary Practice

Robert P. Lavan, Muna Tahir, Christina O’Donnell, Alex Bellenger, Elodie DeBock, Patricia Koochaki

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: canine; health-related quality of life; human-canine bond; validity; reliability; outcomes

Online: 4 August 2023 (14:36:30 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.0365.v1

Reduced Endothelial Nitric Oxide Involvement in Duck Basilar Arterial Relaxation

Siyuan Wu, Tomoki Ootawa, Henry Smith, Ryoya Sekio, Md. Zahorul Islam, Ha Thi Thanh Nguyen, Yasuhiro Uno, Mitsuya Shiraishi, Atsushi Miyamoto

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: cerebral artery; duck; endothelium; highly pathogenic avian influenza; nitric oxide

Online: 3 August 2023 (14:50:39 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1831.v1

Using Machine Learning in Veterinary Medical Education: An Introduction for Veterinary Medicine Educators

Sarah E. Hooper, Kent G. Hecker, Elpida Artemiou

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: machine learning; veterinary medical education; random forest; medical education; artificial intelligence; Python; R; veterinary educators; educational data mining; learning analytics

Online: 26 July 2023 (14:02:31 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1540.v1

Congenital Partial Colonic Agenesis in Dogs and Cats: Clinical, Biological, Diagnostic Imaging, Endoscopic and Histopathologic Characterization. A Retrospective Study of 23 Cases

Paul Remmel, Lucile Gros, Jérémy Mortier, Valérie G Freiche

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Congenital; Colonic Agenesis; Stenosis; Canine; Feline

Online: 24 July 2023 (09:30:00 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0808.v1

Canine Somatic Mutations from Whole Exome Sequencing of B-Cell Lymphomas in Six Canine Breeds

Sungryong Kim, Namphil Kim, Hyo-Min Kang, Hye-Jin Jang, Ki-Jeong Na

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Canine lymphoma; Whole-exome sequencing; B-cell; PARR

Online: 12 July 2023 (09:38:44 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0626.v1

Characterization and Efficacy of Titanium Dioxide Nano-Formulation on Skin Microflora Reduction and Wound Healing in Animals

Noppason Pangprasit, Yada Thammawong, Alongkorn Kulsirorat, Phongsakorn Chuammitri, Aphisek Kongkaew, Montira Intanon, Witaya Suriyasathaporn, Surachai Pikulkaew, Wasana Chaisri

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Animal wound; Anti-biofilm forming; Antimicrobial activities; Skin microflora; Titanium dioxide

Online: 11 July 2023 (03:08:32 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0530.v1

Animal Welfare in the Polish Veterinary Code of Ethics Versus Selected Veterinary Codes of Ethics

Michał Tracz, Agnieszka Jackowska-Tracz, Andrzej Dzikowski

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: veterinary medicine; law; professional ethics; moral philosophy; code of ethics

Online: 10 July 2023 (03:45:11 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.1264.v1

Bronchoalveolar Lavage Cytology in Severe Equine Asthma Syndrome During Asymptomatic, Exacerbation, and Remission Phase: Cytocentrifugated Versus Sedimented Smear Preparations

Maria Morini, Francesca Gobbo, Riccardo Rinnovati, Noemi Romagnoli, Angelo Peli, Chiara Massarenti, Alessandro Spadari, Marco Pietra

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: BAL; Equine Asthma Syndrome; cytocentrifugation; smear; cytology; horse

Online: 19 June 2023 (03:00:20 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202306.1018.v1

Ultrasound-Guided Block of the Sciatic and the Femoral Nerves in Rabbits - A Descriptive Anatomical Study

Robert Trujanovic, Helene Rohrbach

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Rabbit; animal model; peripheral nerve block; regional anaesthesia; sciatic nerve block; femoral nerve block; orthopaedic surgery; cadaver

Online: 14 June 2023 (08:41:02 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202306.0770.v1

Therapeutic Applications of Botulinum Neurotoxins in Veterinary Medicine

Lauretta Turin, Marina Michela Piccione, Fabio Crosa, Paola Dall'Ara, Joel Filipe, Laura Zarucco

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Clostridium botulinum; botulism; neurotoxin; BoNT; therapeutic; antibodies; horse; dog; cat; farm animals

Online: 12 June 2023 (05:23:03 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.2250.v1

Camera-Based Respiration Monitoring of Unconstrained Rodents

Lukas Breuer, Lucas Mösch, Janosch Kunczik, Verena Buchecker, Heidrun Potschka, Michael Czaplik, Carina Barbosa Pereira

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: respiration; automatic monitoring; rodent; rat; animal welfare; refinement; 3R; laboratory animals; camera-based monitoring; breathing

Online: 31 May 2023 (12:56:46 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202305.2248.v1

The Importance of Neutrophils in Osteoarthritis: Current Concepts and Therapeutic Perspectives

Yeganeh Mehrani, Rasool Rahimi, Solmaz Morovati, Hossein Mehrani, Negar Karimi, Samaneh Ghasemi

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Keywords: Osteoarthritis, Neutrophil, Innate Immunity, Neutrophil Extracellular Traps (NET).

Online: 31 May 2023 (12:55:03 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202305.2207.v1

Examining the Veterinary Electronic Antimicrobial Prescription for Dog and Cat in Campania Region, Italy: Corrective Strategies Are Imperative

Valentina Foglia Manzillo, Maria Francesca Peruzy, Manuela Gizzarelli, Berardino Izzo, Paolo Sarnelli, Antonio Carrella, Giuseppina Vinciguerra, Claudia Chirollo, Nour el Houda Ben-Fayala, Ines Balestrino, Gaetano Oliva

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: antimicrobials; companion animals; veterinary electronic prescription; antimicrobial resistance

Online: 31 May 2023 (08:51:16 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202305.1827.v1

Leveraging Data from Spontaneous Animal Disease Models to Streamline Pharmaceutical Research: A Tale of Two Species

Jonathan P Mochel, Karin Allenspach

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: One Health; Comparative Research; Reverse Translation

Online: 26 May 2023 (03:29:17 CEST)

Show abstract| Download PDF| Share

According to data from the U.S FDA, the likelihood of a new drug progressing from Phase I clinical trials to market approval is only 8% (DiMasi et al., 2016). Furthermore, a significant attrition rate of 35% occurs during Phase II studies due to the failure to demonstrate clinical efficacy (Arrowsmith, 2011). These statistics underscore the urgent need to reassess the current research and development (R&D) paradigm. To address this challenge, a promising approach called reverse translational pharmacology (RTP) has emerged, aiming to enhance the predictive value of preclinical models used in biomedical research by leveraging animal models that spontaneously develop analogous diseases to humans (Schneider et al., 2018). The rationale behind RTP is that knowledge gained from clinical trials in canines can subsequently inform and guide human clinical trials, leading to improved outcomes for both species. Additionally, this approach capitalizes on the opportunity to stimulate veterinary drug development by leveraging pharmacokinetic (PK), efficacy, and safety data obtained from human clinical studies (Schneider et al., 2018). The application of reverse translational pharmacology holds immense potential for expediting drug development and advancing medical knowledge. By employing animal models that naturally develop diseases akin to those found in humans, researchers can enhance the predictive capacity of preclinical models, thereby mitigating the high attrition rates encountered in later stages of clinical trials. Moreover, the exchange of knowledge and data between human and veterinary medicine engenders a synergistic relationship, fostering progress in both domains (Schneider et al., 2018). As this innovative approach gains momentum, fostering collaborations between basic and clinician scientists, pharmaceutical companies, and veterinary professionals becomes increasingly imperative. By sharing resources, expertise, and findings, we can pave the way for groundbreaking discoveries and the development of safe and efficacious treatments for diverse diseases. Embracing reverse translational pharmacology offers an avenue to redefine the R&D paradigm, bringing us closer to a future where a higher proportion of drugs successfully traverse the arduous path from the laboratory to market approval, ultimately benefiting patients across species. In this brief commentary, we highlight four examples of diseases where reverse translational modeling has been used to support pharmaceutical research, including some applications developed in our research laboratory (SMART Pharmacology) at the Iowa State University College of Veterinary Medicine. In doing so, this report also seeks to provide a brief overview of the heuristic value of computational approaches in comparative research. To further illustrate the value of these in silico approaches, we deliberately chose to employ some features of ChatGPT to produce the present summary (OpenAI. (2023). GPT-3.5 [ChatGPT]. Retrieved from https://openai.com).

Preprint REVIEW | doi:10.20944/preprints202305.1418.v1

Molecular Profile of Canine Hemangiosarcoma and Potential Novel Therapeutic Targets

Pedro Antônio Bronhara Pimentel, Antonio Giuliano, Paweł M. Bęczkowski, Rodrigo Dos Santos Horta

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: angiosarcoma; dog; NRAS; PIK3CA; VEGF; CDKN2A; PTEN; TP53

Online: 19 May 2023 (09:43:38 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.1379.v1

Haemodynamic Effects of Pimobendan During General Anaesthesia in Healthy Senior Dogs: A Prospective, Randomised, Triple-Blinded, Placebo-Controlled Clinical Study

Ignacio Sández, José Ignacio Redondo, Pablo A. Donati, Jose Gómez

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Pimobendan; anaesthesia; cardiac output; haemodynamic; oesophageal Doppler

Online: 19 May 2023 (04:40:05 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.1329.v1

In Vitro Activity of Ozone/Oxygen Gaseous Mixture against Caprine Herpesvirus Type 1 (CpHV-1) Strain Isolated from Vaginitis in Goat

Edoardo Lillo, Francesco Pellegrini, Annalisa Rizzo, Gianvito Lanave, Claudia Zizzadoro, Vincenzo Cicirelli, Cristiana Catella, Michele Losurdo, Vito Martella, Maria Tempesta, Michele Camero

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Caprine herpesvirus; virucidal activity; Ozone; in vitro; antiviral activity

Online: 18 May 2023 (10:27:21 CEST)

Show abstract| Download PDF| Share

Preprint COMMUNICATION | doi:10.20944/preprints202305.0889.v1

Approaches Used To Construct Antibiograms for Dogs in a Veter-Inary Teaching Hospital in the United States

John E. Ekakoro, Lynn Guptill, Kenitra Hendrix, Melinda Anderson, Audrey Ruple

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Antimicrobials; antimicrobial resistance; antibiograms; dogs

Online: 12 May 2023 (05:14:29 CEST)

Show abstract| Download PDF| Share

Preprint CASE REPORT | doi:10.20944/preprints202305.0616.v1

Treatment of a Large Defect Induced by Atrophic Nonunion of Femoral Fracture in a Dog with Autogenous Coccygeal Bone Grafting

Kyuman Cho, Kilsang Lee, Kyungsik Kang, Minkyung Kim

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: nonunion; femoral fracture; autograft; coccygeal bone; platelet-rich plasma; dog

Online: 9 May 2023 (08:50:29 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.0544.v1

Udder Ultrasonography of Dairy Cows: Investigating the Relationship Between Echotexture, Blood Flow, Somatic Cell Count and Milk Yield During Dry Period and Lactation

Konstantinos S. Themistokleous, Iraklis Papadopoulos, Nikolaos Panousis, Antonios Zdragas, Georgios Arsenos, Evangelos Kiossis

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: milk vein; spectral Doppler; udder echotexture; somatic cell count; milk production; ultrasound; Holstein dairy cows

Online: 8 May 2023 (14:17:24 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.0147.v1

A New Approach to Improving the Quality of Life of Dogs with Hypoadrenocorticism and their Owners’

Julia Hupfeld, Michael Dölle, Holger Volk, Johanna Rieder

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: hypoadrenocorticism; dogs; owners; quality of life

Online: 3 May 2023 (12:33:28 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202304.1270.v1

Effect of Meloxicam in a Protocol of Balanced Anaesthesia with Propofol and Sevoflurane on the α- δ- γ-Tocopherols in Response to Inflammatory Oxidative Stress Induced by Ovariectomy in Dogs

Giovanna Lucrezia Costa, Simona Di Pietro, Vincenzo Nava, Patrizia Licata, Nicola Maria Iannelli, Fabio Leonardi, Francesco Macrì, Diego Iannelli, Federica De Paoli, Daniele Macrì, Vincenzo Ferrantelli, Vito Angileri, Giuseppe Bruschetta, Claudia Interlandi

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Analgesia; Dog; Meloxicam; Oxidative stress; Ovariectomy; Surgery; Tocopherols

Online: 30 April 2023 (09:15:58 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202304.0101.v1

Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study

Dipak Kumar Sahoo, Marilyn Martinez, Kimberly Dao, Vojtech Gabriel, Christopher Zdyrski, Albert E. Jergens, Todd Atherly, Chelsea A. Iennarella-Servantez, Laura E. Burns, Dwayne Schrunk, Donna A Volpe, Karin Allenspach, Jonathan P. Mochel

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: canine; 3D organoid; permeability; Caco-2; colon

Online: 6 April 2023 (14:13:26 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint SHORT NOTE | doi:10.20944/preprints202303.0553.v1

The A(H5N1) Avian Influenza Virus at the Domestic Animal-Wildlife-Human Interface: Issues of Concern

Giovanni Di Guardo

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: A(H5N1) avian influenza virus; Influenza viruses; Virus host range; Zoonotic risk, Human exposure risk; Viral infection; Epidemiology

Online: 31 March 2023 (14:46:25 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202303.0391.v1

Feature Selection in the Context of Prognostic Health Management

Indrawata Wardhana

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: prognosis and health management, preprocessing data, feature extraction, feature selection.

Online: 22 March 2023 (04:31:53 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202303.0339.v1

Level Weights for Modeling with Complex Survey Data

Charles Natuhamya

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: complex survey design; multilevel models; nonresponse; sampling probability; survey data; Uganda; weighting

Online: 20 March 2023 (03:41:30 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202303.0213.v1

Behaviour of Escherichia coli O157:H7 and Listeria Monocyto-Genes in Normal and DFD Beef of an Autochthonous Portuguese Breed

Cristina Saraiva, Sónia Saraiva, Luis Patarata, Maria da Conceição Fontes, Conceição Martins

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: autochthonous breed; beef; DFD meat; Listeria monocytogenes; Escherichia coli O157:H7; ultimate pH.

Online: 13 March 2023 (04:19:07 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202303.0076.v1

Impact Assessment of Free-Roaming Dog Population Management by CNVR in Greater Bangkok

Elly Hiby, Tuntikorn Rungpatana, Alicja Izydorczyk, Craig Rooney, Mike Harfoot, Robert Christley

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Dog; Canine; Catch, Neuter; Vaccinate and Return; CNVR; Dog population management; Rabies; Dog welfare; Impact assessment

Online: 3 March 2023 (14:12:03 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202302.0381.v1

The Use of Drones to Delivery Rift Valley Fever Vaccines in Rwanda: Perceptions and Recommendations

Evan Griffith, Janna Schurer, Billy Mawindo, Rita Kwibuka, Thierry Turibyarive, Hellen Amuguni

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Rift Valley Fever; drones; Rwanda; livestock vaccine supply chain; zoonotic disease

Online: 22 February 2023 (09:01:39 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202301.0462.v1

Plant-based Bone Grafting: The Future of Bone Healing

Camila Silva de Morais Pinheiro, Alcina Vieira De Carvalho Neta, Vicente Ferrer Pinheiro Neto, Claudia Quintino da Rocha Oliveira, Rachel Melo Ribeiro, Antônio Carlos Romão Borges, Marilene Oliveira da Rocha Borges

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Bone healing; , bone fracture; bone graft; herbal medicine; osteogenesis; plants

Online: 26 January 2023 (02:58:19 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202301.0413.v1

Assessment of the Epidemic Potential of the Marek’s Disease Virus in the Russian Federation

Vasily Afonyushkin, Anna Kilp, Tatyana Kalinina, Tatyana Mironova, Natalya Ykovleva, Ludmila Ermakova, Nikolay Donchenko

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: zoonosis; Marek's disease; infections; vesicular enteritis; herpesvirus infection; breast cancer; COVID 19

Online: 23 January 2023 (11:55:46 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202301.0408.v1

Stopping Feline Coronavirus Shedding Prevented Feline Infectious Peritonitis

Diane D. Addie, Flora Bellini, Johanna Covell-Ritchie, Ben Crowe, Sheryl Curran, Mark Fosbery, Stuart Hills, Eric Johnson, Carrie Johnson, Steven Lloyd, Os Jarrett

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: feline coronavirus; feline infectious peritonitis; FIP prevention; GS-441524; chronic enteritis; inflammatory bowel disease; IBD; antiviral; diarrhea; itraconazole.

Online: 23 January 2023 (09:43:21 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202301.0168.v1

Microbiome Responses to Fecal Microbiota Transplantation in Cats with Chronic Digestive Issues

Connie Rojas, Zhandra Entrolezo, Jessica K. Jarett, Guillaume Jospin, Dawn Kingsbury, Alex Martin, Jonathan A. Eisen, Holly H Ganz

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: fecal microbiota transplant; domestic cat; chronic enteropathies

Online: 10 January 2023 (02:15:25 CET)

Show abstract| Download PDF| Supplementary Files| Share

There is growing interest in the application of fecal microbiota transplants (FMTs) in small animal medicine, but there are few published studies that have tested their effectiveness in the domestic cat (Felis catus). Here we use 16S rRNA gene sequencing to examine fecal microbiome changes in 68 domestic cats with chronic digestive issues that underwent FMT treatment using lyophilized stool that was delivered in oral capsules. Fecal samples were collected from FMT recipients before and two weeks after treatment, as well as from their stool donors, and healthy animals. We found that according to their owners, 77% of cats were reported to show improvement in their clinical signs (termed ‘Responders’), and 23% were reported to exhibit no change or a worsening of their clinical signs (termed ‘Non-Responders’). Variation in the fecal microbiomes of FMT recipients most strongly correlated with host clinical signs, diet, and IBD diagnosis. The relative abundances of Collinsella, Negativibacillus, Parabacteroides, and Peptoclostridium changed differentially in FMT recipients. Overall, on average 13% of the bacterial amplicon sequence variants (ASVs) were shared between stool donors and FMT recipients (excluding ASVs already present in FMT recipients prior to treatment). The most commonly shared ASVs were classified as Prevotella 9, Peptoclostridium, Bacteroides, Collinsella and unclassified Lachnospiraceae. Lastly, FMT recipients that had recently taken antibiotics exhibited increases in microbiome similarity to an age-matched healthy reference set compared to other cats. Cats that had diarrhea or diarrhea with vomiting became more similar to healthy cats than did cats exhibiting other clinical signs. Overall, our results suggest that oral capsule FMT treatment was effective in this group of cats and microbiome responses may be modulated by the FMT recipient’s initial presenting clinical signs, prior IBD diagnosis, recent antibiotic use, and their diet.

Preprint REVIEW | doi:10.20944/preprints202212.0424.v1

The Value of N-of-1 Data in Zoological Medicine: A Methodological Review

Charles O. Cummings, Jessica Eisenbarth, David D.R. Krucik

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: systematic review; meta-analysis; evidence synthesis; RCT; N-of-1 trial; single subject design

Online: 22 December 2022 (07:56:51 CET)

Show abstract| Download PDF| Share

N-of-1 data are unavoidable in zoological medicine. Accordingly, zoological medicine clinicians and investigators need research techniques that can make use of these data. This article reviews two methodologies for using both observational and experimental N-of-1 data: 1) systematic reviews and meta-analyses of case reports and 2) prospective N-of-1 trials. Systematic reviews of case reports and other observational evidence are formal, unbiased summaries of clinical characteristics of a particular disease-taxon combination. They offer advantages to narrative reviews by minimizing omission of relevant articles, thereby reducing the potential for mischaracterization of the literature. Meta-analyses are extensions of systematic reviews that quantitatively synthesize the data from the included articles. While valuable, systematic reviews and meta-analyses of case reports can have limited interpretations due to publication bias and confounding present in their source materials. In contrast to case reports, N-of-1 trials are prospective study designs that allow clinicians to make strong inferences about the effect of an intervention in a particular patient. They are double-blinded, single patient, multi-crossover studies that are of particular value in fields where it is difficult to recruit sufficient patients for conventional randomized control trials (RCTs), such as zoological medicine. Because they require multiple crossover periods, N-of-1 trials are ideal for evaluating short-acting interventions in patients with somewhat stable chronic diseases, such as osteoarthritis. More complex than conventional therapeutic trials, N-of-1 trials require prior consideration of how to achieve blinding, appropriate placebo controls, quantitative primary outcomes, analysis methods, and ethical approval. Aggregation of N-of-1 trials allows estimation of the average treatment effect across the population with fewer participants than a conventional RCT. While systematic reviews and meta-analyses of case reports can be used to synthesize the observational N-of-1 data already in existence, N-of-1 trials offer an exciting way to prospectively generate strong evidence that will be useful for evidence-based decision-making.

Preprint ARTICLE | doi:10.20944/preprints202212.0414.v1

Influence of Hermetia Illucens Larvae Meal Dietary Inclusion on Growth Performance, Gut Histological Traits and Stress Parameters in Sparus Aurata

Ambra Rita Di Rosa, Letteria Caccamo, Lidia Pansera, Marianna Oteri, Biagina Chiofalo, Giulia Maricchiolo

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: black soldier fly; fishmeal substitution; gut histology; animal performance; gilthead seabream

Online: 22 December 2022 (03:30:39 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202211.0209.v1

Review on Epidemiological Interface of Tuberculosis At Human Livestock Wildlife in Ethiopia

Henok Mulatu, Shaban Mohammed

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Bovine Tuberculosis; Human, Interface, Livestock, Wildlife,Ethiopia

Online: 11 November 2022 (02:39:22 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202211.0195.v1

Epizootic Haemorrhagic Disease Virus Serotype 8 in Tunisia, 2021

Soufien Sghaier, Corinne Sailleau, Maurilia Marcacci, Sarah Thabet, Valentina Curini, Thameur Ben Hassine, Liana Teodori, Ottavio Portanti, Salah Hammami, Lucija Jurisic, Massimo Spedicato, Lydie Postic, Ines Gazani, Raja Ben Osman, Stephan Zientara, Emmanuel Breard, Paolo Calistri, Juergen A. Richt, Edward C. Holmes, Giovanni Savini, Francesca Di Giallonardo, Alessio Lorusso

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: EHDV; Tunisia; virus characterization; EHDV serotype 8; circulation

Online: 10 November 2022 (09:59:16 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202211.0183.v1

Evidence of Antimicrobial Resistance in Bats and Its Planetary Health Impact for Surveillance of Zoonotic Spillover Events: A Scoping Review

Popy Devnath, Nabil Karah, Jay P Graham, Elizabeth Rose, Muhammad Asaduzzaman

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Antimicrobial resistance (AMR); Bats; Zoonotic spillover; Planetary health; One health

Online: 10 November 2022 (02:35:46 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202209.0283.v1

Identification and Prevalence of Helicobacter Pylori Virulence Genes Baba and Caga in Wolinella Isolates from the Oral Cavity of Dogs

Zahra Jahanshiri, Bahar Nayeri-fasaei, Shahram Jamshidi, Taghi Zahraei-Salehi

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Wolinella; Virulence genes; Helicobacter pylori; genomic homology

Online: 20 September 2022 (02:06:43 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202207.0402.v1

Patterns and Risk Factors of Antibiotic Use in Poultry Farming and the Farmers: A Cross Sectional One-health Study in Pakistan

Um e Habiba, Amjad Khan, Elia John Mmbaga, Muhammad Asaduzzaman

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: antimicrobial resistance; One Health; poultry; poultry farmers; antibiotic use; Pakistan

Online: 26 July 2022 (10:33:42 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202207.0338.v1

Risk Factors for Persistence Infection of Non-typhoidal Salmonella in Poultry Farms, North-Central Nigeria

Abdullahi O. Sanni, Joshua Onyango, Abdulkadir Usman, Latifah O. Abdulkarim, Annelize Jonker, Folorunso O. Fasina

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Non-typhoidal Salmonella; poultry; risk factor; Nigeria; fowl typhoid; pullorum disease

Online: 22 July 2022 (13:12:50 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202207.0315.v1

Protocol of the Dual Burden of Animal and Human Zoonoses: A Systematic Review

Liz P. Noguera Z., Duriya Charypkhan, Simon Rüegg, Sonja Hartnack, Paul Torgerson

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: protocol; review; zoonosis; zoonotic diseases; infectious diseases; burden of diseases; DALY; zDALY; monetary burden; animal losses

Online: 21 July 2022 (08:12:41 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202207.0105.v1

Erythromycin and Melaleuca armillaris Essential Oil Combination against Staphylococcus aureus Isolated from Dairy Cows

Daniel Buldain, Lihuel Gortari Castillo, Andrea Veronica Buchamer, Arnaldo Bandoni, Laura Marchetti, Nora Mestorino

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Melaleuca armillaris; essential oil; erythromycin; Staphylococcus aureus; synergism; mastitis

Online: 7 July 2022 (04:05:55 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202205.0403.v1

Culture-Independent PCR Detection and Differentiation of Mycobacteria spp. in Antemortem Respiratory Samples from African Elephants (Loxodonta africana) and Rhinoceros (Ceratotherium simum, Diceros bicornis) in South Africa

Wynand J. Goosen, Charlene C. Clarke, Léanie Kleynhans, Tanya J. Kerr, Peter Buss, Michele A. Miller

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: African elephants; broncholoalveolar lavage; Hain CMdirect V1.0; ku PCR; Mycobacterium tuberculosis complex; non-tuberculous mycobacteria; rhinoceros; rpoB PCR; trunk wash; Xpert MTB/RIF Ultra

Online: 30 May 2022 (16:33:30 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Medicine and Pharmacology