Adipose tissue undergoes changes with aging, leading to increased adiposity, inflammatory cell infiltration, reduced angiogenesis, heightened oxidative stress, and alterations in its metabolic function. Regular exercise has been recognized as a powerful intervention that can positively influence adipose tissue health and mitigate the effects of aging. However, the molecular mechanisms underlying the benefits of regular exercise on aging adipose tissue function remain poorly understood. Adipokines released through regular exercise play a potential role in mitigating adipose tissue aging, enhancing the metabolism of glucose and lipids, reducing inflammation and fibrosis, and promoting fat browning and thermogenesis. The goal of this review is to offer a comprehensive overview of the benefits of regular exercise in addressing the age-related decline in adipose tissue function. The significance of regular exercise in mitigating metabolic disorders associated with aged adipose tissue will be discussed.

As a new kind of highly compact and efficient micro-channel heat exchanger, printed circuit heat exchanger (PCHE) is a promising candidate satisfying the heat exchange requirements of liquefied natural gas (LNG) vaporization at low and high pressure. The effects of airfoil fin arrangement on heat transfer an flow resistance were numerically investigated using supercritical liquefied natural gas (LNG) as a working fluid. The thermal properties of supercritical LNG were tested by utilizing a REFPROF software database. Numerical simulation was performed using FLUENT. The inlet temperature of supercritical LNG was 121 K,and its pressure was 10.5MPa. The reference mass flow rate of LNG was set 1.22 g/s for the vertical pitch L_v = 1.67 mm and the staggered pitch L_s = 0 mm, with the Reynolds number of about 3750. The SST k-ω model with enhanced wall treatment was selected by comparing with the experimental data. The airfoil fin PCHE had better thermal-hydraulic performance than that of the straight channel PCHE. Moreover, the airfoil fins with staggered arrangement displayed better thermal performance than that of the fins with parallel arrangement. The thermal-hydraulic performance of airfoil fin PCHE was improved with increasing L_s and L_v. Moreover, L_v affected on the Nusselt number and pressure drop of airfoil fin PCHE more obviously. In conclusion, a sparser staggered arrangement of fins showed a better thermal-hydraulic performance in airfoil fin PCHE.