University campuses with native vegetation function as living botanical gardens, biodiversity laboratories and curated plant collections, sharing core missions with formal botanical institutions: floristic inventory, in situ and ex situ plant conservation, scientific interpretation, environmental education and biodiversity stewardship. Against this backdrop, plant blindness—the inability to perceive and value plants in one’s surroundings—remains a structural challenge in botany teaching. This article proposes the floristic inventory of the Tulcán campus (Universidad del Cauca, Popayán, Colombia) as the core of a pedagogical strategy that operates the campus as a non-formal botanical educational institution. A sequential explanatory mixed-methods design was applied: (1) ecological inventory across 25 systematic field trips during 2025; (2) educational design with faculty validation; and (3) a pilot with 142 undergraduate students of Biology and Environmental Engineering. We recorded 160 species in 65 families (83 % native, including endemic and threatened taxa); designed a four-component strategy (cooperative field research, biocultural connection, applied plant ecology, interpretive trails); and observed a descriptive performance gradient favouring field-immersive courses, together with qualitative patterns consistent with plant blindness. The Tulcán campus can be intentionally managed as a living botanical garden delivering inventory, conservation, interpretation and education functions.