Submitted:
01 April 2026
Posted:
01 April 2026
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Abstract
Keywords:
1. Introduction
2. Materials and Methods
2.1. Study Design and Participants
2.2. Foot PVT Procedure
2.3. Sleep Assessment
2.4. Calculation of PAL
2.5. Statistical Analysis
2.5.1. Within-Group Analysis
2.5.2. Between-Group Comparison
2.5.3. Comparison of Participant Characteristics
2.5.4. Correlation Analysis
2.5.5. Sample Size Sensitivity Analysis
3. Results
3.1. Descriptive Statistics of RT in Younger and Older Adults
3.2. Within-Group Analysis (Wilcoxon Signed-Rank Test)
3.3. Between-Group Comparison of dRT
3.4. Between-Group Comparison of Physical Characteristics
3.5. Associations Between dRT and Physical Characteristics and Sleep Measures
4. Discussion
4.1. Main Findings
4.2. Age-Related Slowing of RT
4.3. Dissociation Between Speed and Response Structure
4.4. Stability of Inside–Outside Asymmetry
4.5. Implications for Driving and Pedal Control
4.6. Preservation of Relative Response Relationships
4.7. Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
| RT | Reaction time |
| PVT | Psychomotor Vigilance Test |
| Foot PVT | Foot-response version of the PVT |
| dRT | difference between inside and outside RT |
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| Group | n | Response type | Color | Mean ± SD (ms) |
Median (IQR) (ms) |
Min–Max (ms) |
|---|---|---|---|---|---|---|
| Younger | 20 | Outside_RT | Blue | 697±74 | 693 (51) | 571–847 |
| Inside_RTr | Red | 673± 72 | 683 (33) | 558–784 | ||
| Inside_RTy | Yellow | 662±81 | 692 (74) | 544–802 | ||
| Older | 24 | Outside_RT | Blue | 818±113 | 786 (60) | 620–1035 |
| Inside_RTr | Red | 798±104 | 775 (51) | 635–1023 | ||
| Inside_RTy | Yellow | 781±106 | 770 (100) | 550–966 |
| Group | Contrast | Median (IQR) (ms) |
W | p-value | Effect size (r) |
|---|---|---|---|---|---|
| Younger (n=20) |
dRT | ー20 (51) | 32 | 0.005 | 0.61 |
| dRTr | ー14 (33) | 35 | 0.007 | 0.58 | |
| dRTy | ー27 (74) | 39 | 0.012 | 0.55 | |
| Older (n=24) |
dRT | ー22 (56) | 82 | 0.053 | 0.40 |
| dRTr | ー7 (51) | 114 | 0.317 | 0.21 | |
| dRTy | ー31 (100) | 73 | 0.025 | 0.45 |
| Contrast | Group | n | Mean ± SD (ms) |
Median (ms) | Test | Statistic | p-value | Cohen’s d |
|---|---|---|---|---|---|---|---|---|
| dRT | Younger | 20 | −30±46 | −20 (51) | S | −0.002 | 0.998 | −0.001 |
| Older | 24 | −30±67 | −22 (60) | |||||
| dRTr | Younger | 20 | −23±38 | −14 (33) | M | 203.5 | 0.396 | −0.053 |
| Older | 24 | −20±66 | −7 (51) | |||||
| dRTy | Younger | 20 | −35±55 | −27 (74) | S | 0.113 | 0.911 | 0.034 |
| Older | 24 | −37±73 | −31 (100) |
| Variable | Group | n | Mean ± SD | Median (IQR) | Test | Statistic | p-value | Cohen's d |
|---|---|---|---|---|---|---|---|---|
| Height (cm) | Younger | 20 | 168± 9 | 171 (13) | S | 2.132 | 0.039 | 0.645 |
| Older | 24 | 162± 9 | 162 (13) | |||||
| PAL (METs·h/week) |
Younger | 20 | 4.90± 7.6 | 0.0 (6.0) | M | 113 | 0.002 | -0.821 |
| Older | 24 | 19.62± 23.2 | 15.0 (13.7) |
| Variable | Group | n | Height | PAL | Sleep1 | Sleep2 | Sleep3 | Sleep4 | Sleep5 |
|---|---|---|---|---|---|---|---|---|---|
| dRT | ALL | 44 | 0.029 | 0.149 | 0.048 | 0.052 | 0.083 | 0.009 | −0.177 |
| Younger | 20 | −0.109 | 0.100 | 0.063 | 0.172 | −0.262 | −0.325 | 0.030 | |
| Older | 24 | 0.183 | 0.196 | 0.070 | −0.014 | 0.387 | 0.251 | −0.293 | |
| dRTr | ALL | 44 | −0.082 | 0.196 | 0.087 | −0.003 | 0.059 | 0.065 | −0.185 |
| Younger | 20 | −0.136 | 0.118 | 0.154 | 0.066 | −0.203 | −0.327 | 0.038 | |
| Older | 24 | 0.019 | 0.120 | 0.027 | −0.011 | 0.266 | 0.252 | −0.321 | |
| dRTy | ALL | 44 | 0.119 | 0.069 | 0.010 | −0.005 | 0.098 | −0.029 | −0.207 |
| Younger | 20 | −0.093 | 0.042 | 0.077 | 0.199 | −0.379 | −0.318 | −0.015 | |
| Older | 24 | 0.322 | 0.146 | 0.002 | −0.100 | 0.416 | 0.192 | −0.313 |
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