We pose the Typhoon Engulfment Grand Challenge: determine whether any physically realizable feedback control law can guarantee the safe flight and landing of a commercial aircraft under all extreme, physically admissible typhoon wind fields—or prove that such a guarantee is mathematically impossible. The problem is formulated as a two-player zero-sum differential game between an autopilot (the minimizer, seeking survival) and an adversarial but physics-constrained typhoon (the maximizer, seeking to force the aircraft outside its safe operating envelope). We detail the coupled nonlinear dynamics, define the safe operating set in the airspeed–load-factor plane, and identify four interlocking barriers—high-dimensional Hamilton–Jacobi–Isaacs equations, PDE-constrained adversarial disturbances, hybrid structural failure dynamics, and imperfect observations—that place this problem beyond the reach of any existing mathematical framework. This article serves as a formal statement of the challenge, provides accessible explanations for researchers across disciplines, and charts concrete research directions for communities spanning control theory, aerospace engineering, applied mathematics, machine learning, fluid dynamics, structural mechanics, formal verification, operations research, signal processing, meteorology, and independent researchers worldwide.