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Prevalence of Pre-Eruptive Intracoronal Resorption (PEIR) and Proposal of a Novel Classification. Retrospective Study with the Aid of Cone Beam Computed Tomography (CBCT)

Submitted:

17 December 2025

Posted:

18 December 2025

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Abstract
Background/Objectives: Pre-eruptive intracoronal resorption (PEIR) in impacted or un-erupted teeth often remains un-diagnosed. The aim of this study was to investigate the prevalence of PEIR with the aid of cone-beam computed tomography (CBCT) and propose a new three-dimensional (3-D) classification for the analysis of the lesions. Methods: A total of 164 CBCT of non erupted teeth scans were examined for the presence of PEIR, tooth type, angulation and position. A novel 3-D classification system was proposed and all PEIR lesions were further classified. The classification system was used to stage PEIR lesions, according to their extend from the enamel level apically, the circumferential spread and their proximity to the pulp chamber. Descriptive statistics were used to assess the prevalence and type of resorption. The association between PEIR, demographics, tooth type, position and angulation were studied. The estimation of the multivariate relationship between PEIR, patient’s demographics and tooth characteristics was conducted with the multiple binary logistic regression model. Results: The prevalence of PEIR was 33.5%, affecting mostly maxillary canines, maxillary and mandibular molars. The prevalence of PEIR in ages over 45 years was significantly high (p < 0.001). The presence of PEIR was significantly associated with buccal position (p=0.002) and buccal angulation (p=0.016) of the tooth. Conclusions: Due to the high prevalence of PEIR, CBCT is essential for baseline recording and monitoring of the lesions. The 3-D classification index enables the early detection of PEIR and may critically affect decision-making in restorative, orthodontic and surgical treatment planning.
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Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
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