Submitted:
19 February 2025
Posted:
20 February 2025
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Abstract
Keywords:
1. Introduction
2. Literature Review
2.1. Insufficient Data-
2.2. Social Issues-
2.3. Clinical Implementations-
2.4. High Costs-
2.5. Blackbox Scenario-
2.6. DataAcquisition-
2.7. IntroductionofInnovative and New Generation Tools-
2.8. Missing Compassion -
2.9. DataMisuse-
2.10. Data Privacy and Security-
2.11. Technology Development-
| Serial No | Notations | Different Challenges |
| 1 | ID | INSUFFICIENT DATA |
| 2 | SI | SOCIAL ISSUES |
| 3 | CI | CLINICAL IMPLEMENTATION |
| 4 | HC | HIGH COST |
| 5 | BS | BLACKBOX SCENARIO |
| 6 | DA | DATA AQUISITION |
| 7 | IIN | INTRODUCTION OF INNOVATIVE AND NEW GENERATION TOOLS |
| 8 | MC | MISSING COMPASSION |
| 9 | DM | DATA MISUSE |
| 10 | DPS | DATA PRIVACY AND SECURITY |
| 11 | TD | TECHNOLOGY DEVELOPMENT |
3. Methodology
3.1. Data Collection

3.2. Interpretive Structural Modelling (ISM)-
| Resources | Objectives |
| Iqbal et al., 2023 [27] | Energy efficient supply chain in construction industry |
| Akpinar et al., 2023 [28] | Resilience in maritime business |
| Agarwal et al., 2023 [29] | Adoption of solar renewable energy products in India |
| Gadekar et al., 2024 [30] | Study of the inhibitorsthat affect Industry 4.0 implementationin manufacturing industries of India |
| Asif et al., 2024 [31] | Dairy supply chain |
| Feng et al., 2024 [32] | Digital innovation in manufacturing enterprises |
3.2.1. Structural Self Interaction Matrix (SSIM)
3.2.2. Reachability Matrix
3.2.3. LevelPartition
3.2.4. Formation of Interpretive Structural Model (ISM)

3.2.5. MICMAC Analysis

4. Results
5. Conclusions
Author Contributions
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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| Identified challenges | Notations | Key Resources |
| Insufficient data | ID | Neyigapula,2023[8], Paul et al., 2020 [6], Bartoletti, 2019 [9], Shah & Chircu, 2018 [10] |
| Social issues | SI | Gille et al., 2020 [5], Khaled et al., 2019 [11] |
| Clinical implementation | CI | Aung et al., 2021 [4], Reddy et al., 2019 [12], Shah & Chircu, 2018 [10] |
| High cost | HC | Aung et al., 2021 [4], Jimma, 2023 [3] |
| Black-box scenario | BS | Wang et al., 2023 [13], Srinivasu et al., 2022 [14], Reddy et al., 2019 [12] |
| Data acquisition | DA | Aung et al., 2021 [4], Mueller et al., 2022 [15] |
| Introduction of innovative and new-generation tools | IIN | Wang et al., 2023 [13], Rebelo et al., 2023 [16], Van Mens et al., 2022 [17] |
| Missing compassion | MC | Aung et al., 2021 [4], Khaled et al., 2019 [11] |
| Data misuse | DM | Bartoletti, 2019 [9], Aung et al., 2021 [4] |
| Data privacy and security | DPS | Shah & Chircu, 2018 [10], Bartoletti, 2019 [9], Sun et al., 2019 [7] |
| Technology development | TD | Wang et al., 2023, Rebelo et al., 2023 [16] |
| Notation | ID | SI | CI | HC | BS | DA | IIN | MC | DM | DPS | TD |
| ID | O | V | V | V | O | V | O | O | V | V | |
| SI | V | V | O | O | V | O | O | O | V | ||
| CI | V | A | A | V | O | O | A | V | |||
| HC | A | V | O | O | A | O | |||||
| BS | A | V | O | O | O | V | |||||
| DA | V | O | O | V | V | ||||||
| IIN | A | A | A | A | |||||||
| MC | O | O | V | ||||||||
| DM | V | V | |||||||||
| DPS | V | ||||||||||
| TD |
| ID | SI | CI | HC | BS | DA | IIN | MC | DM | DPS | TD | Driving powers | |
| ID | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 7 |
| SI | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5 |
| CI | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4 |
| HC | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2 |
| BS | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 5 |
| DA | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 7 |
| IIN | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| MC | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 6 |
| DM | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 7 |
| DPS | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 5 |
| TD | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2 |
| Total dependencies | 1 | 2 | 8 | 9 | 4 | 1 | 11 | 1 | 1 | 4 | 9 | 1 |
| Factor No | Reachability Set | Antecedent Set | Interaction Set | Level |
| 1 - ID | 1,3,4,5,7,10,11 | 1 | 1 | One |
| 2 - SI | 2,3,4,7,11 | 2,8 | 2 | Two |
| 3 - CI | 3,4,7,11 | 1,2,3,5,6,8,9,10 | 3 | Three |
| 4 - HC | 4,7 | 1,2,3,4,5,6,8,9,10 | 4 | Four |
| 5 - BS | 3,4,5,7,11 | 1,5,6,9 | 5 | Two |
| 6 - DA | 3,4,5,6,7,10,11 | 6 | 6 | One |
| 7 - IIN | 7 | 1,2,3,4,5,6,7,8,9,10,11 | 7 | Five |
| 8 - MC | 2,3,4,7,8,11 | 8 | 8 | One |
| 9 - DM | 3,4,5,7,9,10,11 | 9 | 9 | One |
| 10 - DPS | 3,4,7,10,11 | 1,6,9,10 | 10 | Two |
| 11 - TD | 7,11 | 1,2,3,5,6,8,9,10,11 | 11 | Four |
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