Submitted:
12 December 2025
Posted:
17 December 2025
You are already at the latest version
Abstract
Keywords:
Introduction
Literature Review
Data and Methods
Defining Technology and Technology Transfer
A Human-Centered Framework
Study Data
Analytical Methods
Analysis and Results
Applying the Human-Centered Framework
MCMC Simulation 1 Results
MCMC Simulation 2 Results
Discussion
Merits of the Human-Centered Framework
Interpretation of MCMC Simulation Results
Meaning of Results
Implications
Limitations
Recommendations for Future Research
Conclusions
Supplementary Materials
Acknowledgments
Funding sources
Competing interests
Data availability
Ethics Statement
Declaration regarding artificial intelligence (AI) and AI-assisted technologies
References
- Afonso, O., Monteiro, S., & Thompson, M. J. R. (2010). A growth model for the quadruple helix innovation theory [Working paper]. Retrieved June 30, 2025 from http://www3.eeg.uminho.pt/economia/nipe/docs/2010/NIPE_WP_12_2010.pdf.
- Akard, P. (1995). The return of the market?: Reflections on the real “conservative tradition” in U.S. policy discourse. Sociological Inquiry, 65(3-4), 286-308. [CrossRef]
- Aksom, H., & Tymchenko, I. (2020). How institutional theories explain and fail to explain organizations. Journal of Organizational Change Management, 33(7), 1223-1252. [CrossRef]
- Allard, G., Miner, J., Ritter, D., Stark, P., & Stevens, A. J. (2021). AUTM U.S. licensing activity survey, 2020: A survey report of technology licensing and related activity for U.S. academic and nonprofit research institutions and technology investment firms. Association of University Technology Managers. Retrieved January 23, 2024 from https://autm.net/AUTM/media/SurveyReportsPDF/FY20-US-Licensing-Survey-FNL.pdf.
- American Association for the Advancement of Science. (2022). Federal R&D and facilities funding by performer, 1967-2021 [Data set]. Retrieved June 11, 2025 from https://www.aaas.org/programs/r-d-budget-and-policy/historical-trends-federal-rd.
- Anatan, L. (2015). Conceptual issues in university to industry knowledge transfer studies: A literature review. Procedia - Social and Behavioral Sciences, 211, 711-717. [CrossRef]
- Andersén, J., Jansson, C., & Ljungkvist, T. (2019). Can environmentally oriented CEOs and environmentally friendly suppliers boost the growth of small firms? Business Strategy and the Environment, 29(2), 325-334. [CrossRef]
- Andrews, M., & Boklage, A. (2023). Supporting inclusivity in STEM makerspaces through critical theory: A systematic review. Journal of Engineering Education, 113(4), 787-817. [CrossRef]
- Arenas, J. J., & González, D. (2018). Technology transfer models and elements in the university-industry collaboration. Administrative Sciences, 8(2), 1-17. [CrossRef]
- Arqué-Castells, P., Cartaxo, R. M., García-Quevedo, J., & Godinho, M. M. (2016). Royalty sharing, effort and invention in universities: Evidence from Portugal and Spain. Research Policy, 45(9), 1858-1872. [CrossRef]
- Bacharach, S. B. (1989). Organizational theories: Some criteria for evaluation. Academy of Management Review, 14(4), 496-515. [CrossRef]
- Barney, J. (1991). Firm resources and sustained competitive advantage. Journal of management, 17(1), 99-120. [CrossRef]
- Barney, J., Wright, M., & Ketchen Jr, D. J. (2001). The resource-based view of the firm: Ten years after 1991. Journal of management, 27(6), 625-641. [CrossRef]
- Barros, M. V., Ferreira, M. B., do Prado, G. F., Piekarski, C. M., & Picinin, C. T. (2020). The interaction between knowledge management and technology transfer: A current literature review between 2013 and 2018. The Journal of Technology Transfer, 45(5), 1585-1606. [CrossRef]
- Barter, N., & Russell, S. (2013). Organisational Metaphors and Sustainable Development: Enabling or Inhibiting? Sustainability Accounting Management and Policy Journal, 4(2), 145-162. https://www. [CrossRef]
- Battaglia, D., Paolucci, E., & Ughetto, E. (2021). The role of Proof-of-Concept programs in facilitating the commercialization of research-based inventions. Research Policy, 50(6), 104268. [CrossRef]
- Battistella, C., De Toni, A. F., & Pillon, R. (2016). Inter-organisational technology/knowledge transfer: A framework from critical literature review [Periodical]. Journal of Technology Transfer(5), 1195. [CrossRef]
- Bengoa, A., Maseda, A., Iturralde, T., & Aparicio, G. (2020). A bibliometric review of the technology transfer literature. The Journal of Technology Transfer, 46, 1514-1550. [CrossRef]
- Benson, D. (2012). The ballet of the planets: A mathematician’s musings on the elegance of planetary motion. Oxford University Press.
- Bergenholtz, C., & Busch, J. (2015). Self-fulfillment of social science theories. Philosophy of the Social Sciences, 46(1), 24-43. [CrossRef]
- Borge, L., & Bröring, S. (2017). Exploring Effectiveness of Technology Transfer in Interdisciplinary Settings: The Case of the Bioeconomy. Creativity and Innovation Management, 26(3), 311-322. [CrossRef]
- Bozeman, B. (2000). Technology transfer and public policy: A review of research and theory. Research Policy, 29(4,5), 627-655. [CrossRef]
- Bozeman, B., Rimes, H., & Youtie, J. (2015). The evolving state-of-the-art in technology transfer research: Revisiting the contingent effectiveness model. Research Policy, 44(1), 34. http://. [CrossRef]
- Cai, Y. (2015). What contextual factors shape ‘Innovation in Innovation’? Integration of insights from the Triple Helix and the institutional logics perspective. Social Science Information, 54(3), 299-326. [CrossRef]
- Cai, Y., & Amaral, M. (2021). The triple helix model and the future of innovation: A reflection on the triple helix research agenda. Triple Helix, 8(2), 217-229. [CrossRef]
- Campanella, F., Peruta, M. R. D., Bresciani, S., & Dezi, L. (2017). Quadruple Helix and firms’ performance: An empirical verification in Europe. The Journal of Technology Transfer, 42(2), 267-284. [CrossRef]
- Carayannis, E. G., Barth, T. D., & Campbell, D. F. J. (2012). The Quintuple Helix Innovation Model: Global warming as a challenge and driver for innovation. Journal of Innovation and Entrepreneurship, 1(1), 2. [CrossRef]
- Carayannis, E. G., & Campbell, D. F. (2010). Triple Helix, Quadruple Helix and Quintuple Helix and how do knowledge, innovation and the environment relate to each other?: A proposed framework for a trans-disciplinary analysis of sustainable development and social ecology. International Journal of Social Ecology and Sustainable Development (IJSESD), 1(1), 41-69. [CrossRef]
- Cloitre, A., Dos Santos Paulino, V., & Theodoraki, C. (2023). The quadruple/quintuple helix model in entrepreneurial ecosystems: An institutional perspective on the space case study. R&D Management, 53(4), 675-694. [CrossRef]
- Coppedge, M. (2012). Criteria for evaluating causal theories. In Democratization and Research Methods (pp. 49-75). Cambridge University Press. [CrossRef]
- Costa, L. s. A., Cool, K., & Dierickx, I. (2012). The competitive implications of the deployment of unique resources. Strategic Management Journal, 34(4), 445-463. [CrossRef]
- Cummings, S., & Thanem, T. (2002). Essai: The Ghost in the Organism. Organization studies, 23(5), 817-839. [CrossRef]
- Cunha, E. P. (2022). Herbert Simon’s epistemological itinerary on the limits of rationality. Organizações & Sociedade, 29(103), 614-637. [CrossRef]
- Curado, C., & Bontis, N. (2006). The knowledge-based view of the firm and its theoretical precursor. International Journal of Learning and Intellectual Capital, 3(4), 367-381. [CrossRef]
- Cyert, R. M., & March, J. G. (1963). A behavioral theory of the firm. Prentice-Hall.
- Deakin, M. (2022). Triple, Quadruple and N-Tuple Helices: The RIS3 and EDP of a Higher-Order Policy Model. Triple Helix Journal, 9(1), 32-42. [CrossRef]
- DiMaggio, P. J., & Powell, W. W. (1983). The iron cage revisited: Institutional isomorphism and collective rationality in organizational fields. American Sociological Review, 48(2), 147-160. [CrossRef]
- Eðvarðsson, I. R., & Óskarsson, G. K. (2011). Outsourcing in knowledge-based service firms. International Journal of Knowledge-Based Organizations, 1(3), 39-55. [CrossRef]
- Estrada, F. (2010). Economics and rationality of organizations: An approach to the work of Herbert A. Simon. SSRN Electronic Journal. [CrossRef]
- Fawcett, J. (2005). Criteria for evaluation of theory. Nursing Science Quarterly, 18(2), 131-135. [CrossRef]
- Federal Reserve Bank of Minneapolis. (2025). Consumer price index, 1913-present: Historical data from the era of the modern U.S. consumer price index (CPI) [Data set]. Retrieved June 1, 2025 from https://www.minneapolisfed.org/about-us/monetary-policy/inflation-calculator/consumer-price-index-1913-.
- Felin, T., & Foss, N. J. (2009). Social reality, the boundaries of self-fulfilling prophecy, and economics. Organization Science, 20(3), 654-668. [CrossRef]
- French, S., Green, S., O’Connor, D., McKenzie, J. E., Francis, J., Michie, S.,... Grimshaw, J. (2012). Developing theory-informed behaviour change interventions to implement evidence into practice: A systematic approach using the theoretical domains framework. Implementation Science, 7(1). [CrossRef]
- Gagné, M. (2018). From strategy to action: Transforming organizational goals Into organizational fehavior. International Journal of Management Reviews, 20(S1). [CrossRef]
- Ghoshal, S., & Moran, P. (1996). Bad for practice: A critique of the transaction cost theory. The Academy of Management Review, 21(1), 13-47. [CrossRef]
- Goolkasian, P. (1996). Picture-word differences in a sentence verification task. Memory & Cognition, 24(5), 584-594. [CrossRef]
- Gotham, D., Meldrum, J., Nageshwaran, V., Counts, C., Kumari, N., Martín, M. d. M.,... Post, N. (2016). Global health equity in United Kingdom university research: A landscape of current policies and practices. Health Research Policy and Systems, 14(1). [CrossRef]
- Grant, C., & Osanloo, A. F. (2014). Understanding, selecting, and integrating a theoretical framework in dissertation research: Creating the blueprint for your “house”. Administrative Issues Journal Education Practice and Research, 4(2). [CrossRef]
- Grant, R. M. (1996). Toward a knowledge-based theory of the firm. Strategic Management Journal, 17, 109-122. [CrossRef]
- Gresov, C., & Drazin, R. (1997). Equifinality: Functional equivalence in organization design. The Academy of Management Review, 22(2), 403-428. [CrossRef]
- Hardt, Ł. (2011). An inquiry Into the explanatory virtues of transaction cost economics. Journal of Philosophical Economics, Volume V Issue 1(Articles). [CrossRef]
- Hayward, T., & Broady-Preston, J. (1994). Macroeconomic change: Information and knowledge. Journal of information science, 20(6), 377-387. [CrossRef]
- Holdsworth, D. G. (2011). Economics and the limits of optimization: Steps towards extending Bernard Hodgson’s moral science. Journal of business ethics, 108(1), 37-48. [CrossRef]
- Jabareen, Y. (2009). Building a conceptual framework: philosophy, definitions, and procedure. International journal of qualitative methods, 8(4), 49-62.
- Kass, R. E., & Raftery, A. E. (1995). Bayes factors. Journal of the American Statistical Association, 90(430), 773-795. [CrossRef]
- Keen, S. (2001). Debunking economics: The naked emperor of the social sciences. Zed Books.
- Keen, S. (2011). Debunking economics: The naked emperor dethroned? Zed Books Ltd.
- König, J., Suwala, L., & Delargy, C. (2020). Helix models of innovation and sustainable development goals. In W. Leal Filho, A. Azul, L. Brandli, A. Lange Salvia, & T. Wall (Eds.), Industry, Innovation and Infrastructure. Encyclopedia of the UN Sustainable Development Goals (pp. 473-487). Springer.
- Kunwar, R. R., & Ulak, N. (2024). Extension of the Triple Helix to Quadruple to Quintuple Helix Model. Journal of Apf Command and Staff College, 7(1), 241-280. 10.3126/japfcsc.v7i1.67006.
- Leydesdorff, L., & Etzkowitz, H. (1996). Emergence of a Triple Helix of university—industry—government relations. Science and Public Policy, 23(5), 279-286. [CrossRef]
- Leydesdorff, L., & Etzkowitz, H. (1998). Triple Helix of innovation: Introduction. Science and Public Policy, 25(6), 358-364. [CrossRef]
- Leydesdorff, L., & Smith, H. L. (2022). Triple, Quadruple, and higher-order helices: Historical phenomena and (neo-)evolutionary models. Triple Helix Journal, 9(1), 6-31. [CrossRef]
- Lopez, N. R., Cabal, J. V. A., Cuinas, M. C., & Fernndez, F. O. (2023). Applicability of technology maturity level evaluation methodologies within small- and medium-sized organizations: Prospects and proposals. Systems, 11(8), 387. [CrossRef]
- Mahoney, J. T. (2001). A resource-based theory of sustainable rents. Journal of management, 27(6), 651-660. [CrossRef]
- Marcinkowska, E. (2015). Concept of transaction costs and its influence on the development of offshore outsourcing. China-Usa Business Review, 14(3). [CrossRef]
- Maslow, A. H. (1943). A theory of human motivation. Psychological review, 50(4), 370. [CrossRef]
- McInerney, C. R. (2002). Knowledge management and the dynamic nature of knowledge. Journal of the American society for information science and technology, 53(12), 1009-1018. [CrossRef]
- Meier, C., & Jäckli, U. (2023). Linking business ecosystems and transaction cost theory: Between market and hierarchy and the role of power. International Journal of Management Knowledge and Learning, 12. [CrossRef]
- Meyer, J. W., & Rowan, B. (1977). Institutionalized organizations: Formal structure as myth and ceremony. The American journal of sociology, 83(2), 340-363. [CrossRef]
- Mineiro, A. A. d. C., Arantes, R. d. C., Vieira, K. C., Castro, C. C., Carvalho, E. G., & Amaral, M. G. d. (2021). Business practices for strengthening the Quadruple and Quintuple Helix: A study using structural equation modeling. International Journal of Innovation Science, 15(1), 1-18. [CrossRef]
- Miranda, S. M., & Kim, Y. M. (2006). Professional versus political contexts: Institutional mitigation and the transaction cost heuristic in information systems outsourcing. Mis Quarterly, 30(3), 725-753. [CrossRef]
- Mohammad, I., Ronggo, A., & Akhmad, F. (2017). Maturity level of information technology using Cobit framework 4.1 (Case study: Cloud computing service provider). Jurnal Ilmiah Kursor: Menuju Solusi Teknologi Informasi, 9(2). [CrossRef]
- Mulder, P., & Bergh, J. C. J. M. v. d. (2001). Evolutionary economic theories of sustainable development. Growth and Change, 32(1), 110-134. [CrossRef]
- Munteanu, R. (2012). Stage of development and licensing university inventions. International Journal of Management and Enterprise Development, 12(1). [CrossRef]
- Musser, G. (2015). Spooky action at a distance: The phenomenon that reimagines space and time--and what it means for black holes, the Big Bang, and theories of everything. Macmillan.
- Mutlu, C., & Arikboga, F. Ş. (2023). Evolution of Triple and Quadruple Helix Model to Qintuple Helix Model: A bibliometic analysis. International Journal of Western Black Sea Social and Humanities Sciences, 7(2), 246-272. [CrossRef]
- Nassani, L. M., Javed, K., Amer, R. S., Pun, M. H. J., Abdelkarim, A. Z., & Fernandes, G. V. O. (2024). Technology readiness level of robotic technology and artificial intelligence in dentistry: A comprehensive review. Surgeries, 5(2), 273-287. https://dor.org/10.3390/surgeries5020025.
- National Institute of Standards and Technology. (2022). Federal laboratory technolgy transfer fiscal year 2019: Summary report to the President and the Congress. U.S. Department of Commerce. Retrieved November 1, 2023 from https://www.nist.gov/system/files/documents/2022/09/29/FY2019%20Federal%20Technology%20Transfer%20Report.pdf.
- In The rate and direction of inventive activity: Economic and social factors, 1 ed.; Nelson, R. R. (Ed.). (1962). The rate and direction of inventive activity: Economic and social factors (1 ed., Vol. 1925). Princeton University Press. https://www.nber.org/books-and-chapters/rate-and-direction-inventive-activity-economic-and-social-factors.
- Nolte, W. L. (2008). Did I ever tell you about the whale?: Or measuring technology maturity. Information Age Publishing.
- Norman, G. A. V., & Eisenkot, R. (2017). Technology transfer: From the research bench to commercialization. JACC: Basic to Translational Science, 2(2), 197-208. [CrossRef]
- Noya, S., Taneo, S. Y. M., Melany, M., & Widyaningrum, S. (2024). Collaboration with Triple Helix: The mediating effect of mass media in expanding SMEs’ information access. Quality Innovation Prosperity, 28(1), 67-87. [CrossRef]
- Plummer, M., Best, N., Cowles, K., Vines, K., Sarkar, D., Bates, D.,... Magnusson, A. (2020). coda: Output analysis and diagnostics for MCMC (Version 0.19-4.1) [Software]. The R Foundation. Retrieved January 21, 2024 from https://cran.r-project.org/web/packages/coda/index.html.
- Plummer, M., Stukoalov, A., & Denwood, M. (2023). rjags: Bayesian graphical models using MCMC (Version 4-15) [Software]. The R Foundation. Retrieved April 2, 2025 from https://mcmc-jags.sourceforge.io.
- Posit Team. (2025). RStudio: Integrated development environment for R (Version 2025.05.01 Build 513) [Software]. Posit Software, PBC. Retrieved June 8, 2025 from https://www.posit.co.
- Prodan, I., Drnovsek, M., & Ulijn, J. (2009). A conceptual framework for studying a technology transfer from academia to new firms. In R. Oakey, A. Groen, G. Cook, & P. van der Sijde (Eds.), New Technology-Based Firms in the New Millennium: The Production and Distribution of Knowledge (Vol. 7, pp. 185-203). Emerald Group Publishing Limited. [CrossRef]
- Puzon, K., & Gisselquist, R. M. (2023). Theoretical models of inequality: Examples From rational choice theory and behavioural economics. International Social Science Journal, 73(248), 325-338. [CrossRef]
- Queiroz, M. M., Fosso Wamba, S., Chiappetta Jabbour, C. J., Lopes de Sousa Jabbour, A. B., & Machado, M. C. (2022). Adoption of Industry 4.0 technologies by organizations: A maturity levels perspective. Annals of Operation Research, 1-27. [CrossRef]
- Raftery, A. E., & Lewis, S. M. (1996). Implementing MCMC. In W. R. Gilks, D. J. Spiegelhalter, & S. Richardson (Eds.), Markov chain Monte Carlo in practice (pp. 115-130). Chapman & Hall.
- Rybicka, J., Tiwari, A., & Leeke, G. A. (2016). Technology readiness level assessment of composites recycling technologies. Journal of Cleaner Production, 112, 1001-1012. 10.1016/j.jclepro.2015.08.104.
- Schacht, W. H. (2012). The Bayh-Dole act: selected issues in patent policy and the commercialization of technology. (RL30276). Washington, DC: Library of Congress. Retrieved January 9, 2020 from http://crsreports.congress.gov.
- Schumacher, H., & Thysen, H. C. (2022). Equilibrium contracts and boundedly rational expectations. Theoretical Economics, 17(1), 371-414. [CrossRef]
- Scott, W. R. (2005). Institutional theory: Contributing to a theoretical research program. In K. G. Smith & M. A. Hitt (Eds.), Great minds in management: The process of theory development. Oxford University Press. Retrieved June 29, 2025 from https://www.researchgate.net/profile/W-Scott/publication/265348080_Institutional_Theory_Contributing_to_a_Theoretical_Research_Program/links/54de42450cf2966637857c60/Institutional-Theory-Contributing-to-a-Theoretical-Research-Program.pdf.
- Shafeey, T. E., & Trott, P. (2014). Resource-based competition: Three schools of thought and thirteen criticisms. European Business Review, 26(2), 122-148. [CrossRef]
- Shah, P., Vaughan, G., & Ledley, F. D. (2023). Comparing the economic terms of biotechnology licenses from academic institutions with those between commercial firms. PLoS ONE, 18(3), e0283887. [CrossRef]
- Simon, H. A. (1945/1997). Administrative behavior: A study of decision-making processes in administrative organization 4th ed., Vol. [Non-fiction]. The Free Press. (Original work published 1945).
- Simon, H. A. (1955). A behavioral model of rational choice. The Quarterly Journal of Economics, 69(1), 99-118. http://www.suz.uzh.ch/dam/jcr:ffffffff-fad3-547b-ffff-fffff0bf4572/10.18-simon-55.pdf.
- Simon, H. A. (1957). Models of man, social and rational: Mathematical essays on rational human behavior in society setting. John Wiley and Sons.
- Simon, H. A. (1972). Theories of bounded rationality. In C. B. McGuire & R. Radner (Eds.), Decision and organization: A volume in honor of Jacob Marschak (pp. 161-176). North-Holland Publishing Company.
- Simon, H. A. (1982). Models of bounded rationality. MIT Press.
- Smart, J., & Benaroya, H. (2016). An examination of non-linear and passive technology transfer in the space sector: Consideration of the Contingent Effectiveness Model as a basis for formal modeling. Space policy, 38, 39-47. [CrossRef]
- Srivastava, B., & Mir, R. (2022). The knowledge based view of the firm: An assessment. Journal of Organizational Psychology, 22(3). [CrossRef]
- Steinmann, B., Klug, H. J. P., & Maier, G. W. (2018). The path is the goal: How transformational leaders enhance followers’ job attitudes and proactive behavior. Frontiers in Psychology, 9. [CrossRef]
- Sung, W., & Kim, C. (2021). A study on the effect of change management on organizational innovation: Focusing on the mediating effect of members’ innovative behavior. Sustainability, 13(4), 2079. 10.3390/su13042079.
- The R Foundation. (2023). The R project for statistical computing (Version 4.2.3) [Software]. The R Foundation. https://www.R-project.org.
- Thursby, J. G., & Thursby, M. C. (2001). Industry perspectives on licensing university technologies: Sources and problems. Industry and Higher Education, 15(4), 289-294. [CrossRef]
- Townes, M. S. (2022). The influence of technology maturity level on the incidence of university technology transfer and the implications for public policy and practice (Publication Number 29209868) [Doctoral dissertation, Saint Louis University]. ProQuest.
- Townes, M. S. (2024). The role of technology maturity level in the cccurrence of university technology transfer. Journal of the Knowledge Economy. [CrossRef]
- Townes, M. S. (2025). The conceptualisation of techology in scholarly research and public policy regarding university technology transfer. International Journal of Technology Transfer and Commercialisation, 21(3). [CrossRef]
- U.S. Bureau of Economic Analysis. (2011). Regional input-output modeling system (RIMS II): An essential tool for regional developers and planners. Washington, D.C., United States of America: U.S. Department of Commerce. Retrieved May 29, 2025 from https://www.bea.gov/resources/methodologies/RIMSII-user-guide.
- U.S. Bureau of Economic Analysis. (2025, March 28). Gross domestic product by state and personal income by state, 4th quarter 2024 and preliminary 2024 [Data set]. U.S. Department of Commerce. Retrieved May 29, 2025 from https://www.bea.gov/data/gdp/gdp-state.
- Valentinov, V., & Iliopoulos, C. (2024). The idea of adaptation in transaction cost economics: An application to stakeholder theory. Society and Business Review, 19(3), 473-495. https://10.1108/sbr-03-2023-0072.
- Valentinov, V., & Roth, S. (2024). Relationality in transaction cost economics and stakeholder theory: A new conceptual framework. Business Ethics the Environment & Responsibility, 33(3), 535-546. [CrossRef]
- von Bertalanffy, L. (1969). General system theory: Foundations, development, applications. George Braziller, Inc.
- Walker, A., & Wing, C. K. (1999). The relationship between construction project management theory and transaction cost economics. Engineering Construction & Architectural Management, 6(2), 166-176. [CrossRef]
- Weber, M. (1921-1922/2019). Economy and society K. Tribe, Ed. & Trans. Harvard University Press. (Original work published 1921-1922).
- Williamson, O. E. (1998). Transaction cost economics: How it works; where it is headed. De economist, 146(1), 23-58. [CrossRef]
- Williamson, O. E. (2013). The transaction cost economics project: The theory and practice of the governance of contractual relation. Edward Elgar Publishing.
- Wilton, R., & Harley, T. (2018). The criteria used for choosing between competing theories. In Science and Psychology (pp. 43-60). Routledge. [CrossRef]
- Wright, P. M. (2001). Human resources and the resource based view of the firm. Journal of management, 27(6), 701-721. [CrossRef]














| Federal | Academic | Total | |
| Disclosures for new inventions | 26,966 | 127,745 | 154,711 |
| U.S. patent applications | 12,941 | 80,834 | 93,775 |
| U.S. patents allowed | 11,744 | 36,313 | 48,057 |
| Unique inventions licensed | 2,839 | 13,598 | 16,437 |
| Unique inventions licensed as a percentage of invention disclosures |
10.53% | 10.64% | 10.62% |
| Unique inventions licensed as a percent of patent applications |
21.94% | 16.82% | 17.53% |
| Unique inventions licensed as a percentage of patents allowed |
24.17% | 37.45% | 34.20% |
| Framework | Primary Purpose | Core Premises | Critiques and Criticisms | Sources |
| Neo-Classical Economics | To explain and predict how scarce resources are allocated | Resources are scarce and competition is unrestricted Markets are the most efficient means of allocating scarce resources Decision makers have perfect information Individuals make rational choices to maximize utility Profit maximization is the dominant goal |
Reifies the organization construct Assumptions are highly idealized and rarely, if ever, achieved in the real world Core premises embed normative biases Presents a static view Ignores the influence of social institutions |
Holdsworth (2011); Keen (2001, 2011); Mulder and Bergh (2001); Puzon and Gisselquist (2023) |
| Transaction Cost Economics | To explain why profit-seeking organizations (i.e., firms) exist, how they are structured, and why they adopt given governance mechanisms | Profit maximization is the dominant goal of profit-seeking organizations Agents may maximize their own utility at the expense of the organization Asset specificity, uncertainty, and transaction frequency mediate a firm’s choice of governance mechanisms |
Reifies the organization construct Overemphasizes the assumptions of rationality and opportunism Presents a static view Ignores the influence of social norms and relationships Ignores motivations of organizational behavior other than profit |
Ghoshal and Moran (1996); Hardt (2011); Mahoney (2001); Marcinkowska (2015); Meier and Jäckli (2023); Miranda and Kim (2006); Valentinov and Iliopoulos (2024); Valentinov and Roth (2024); Walker and Wing (1999); Williamson (1998); Williamson (2013) |
| Resource-Based View | To explain differences in the performance of profit-seeking organizations To explain how profit-seeking organizations create and maintain a sustainable advantage |
Profit maximization is the dominant goal of profit-seeking organizations Profit-seeking organizations derive their competitive advantage from internal resources that are valuable, rare, imperfectly imitable, and non-substitutable |
Reifies the organization construct Lack of actionable insights Presents a static view Neglects important external factors Ignores institutional factors such as industry norms and cultural elements that influence how firms acquire, manage, and use resources |
Andersén et al. (2019); Barney (1991); Barney et al. (2001); Costa et al. (2012); Eðvarðsson and Óskarsson (2011); Mahoney (2001); Shafeey and Trott (2014); Wright (2001) |
| Knowledge-Based View | To explain differences in the performance of profit-seeking organizations To explain how knowledge assets influence the competitive advantage and performance of profit-seeking organizations |
Profit maximization is the dominant goal of profit-seeking organizations Knowledge (in the lay meaning of the term) is an internal resource that organizations use to create and sustain their competitive advantages |
Reifies the organization construct Presents a static view Conceptually vague Ignores other organizational and environmental factors that significantly affect competitiveness Ignores sociological factors, such as power dynamics, that significantly influence how knowledge is shared and used |
Curado and Bontis (2006); Grant (1996); McInerney (2002); Srivastava and Mir (2022) |
| Institutional Theory | To explain how rules, norms, and patterns of behaviors (i.e., institutions) influence the actions of individuals and organizations. To explain stability and change within social systems. |
External pressures influence the actions of organizations The strategies and activities of organizations are linked to cultural and social frameworks in their environment |
Definition of an institution is ambiguous Assumptions and premises are not empirically validated to a sufficient degree Emphasizes organizational stability and ignores agency and innovation Does not adequately explain why organization members modify institutions Ignores certain sociological factors like power dynamics |
Aksom and Tymchenko (2020); DiMaggio and Powell (1983); Meyer and Rowan (1977); Scott (2005) |
| Contingent Effectiveness Model | To organize technology transfer literature To understand how specific contextual conditions either facilitate or impede efficient and effective transfer of technology from one party to another |
The efficiency and effectiveness of technology transfer is dependent on organizational, social, and environmental conditions (i.e., contingencies) | Primarily conceptual Reifies organization construct Assumptions and premises are not empirically validated to a sufficient degree Application is difficult Lacks well-defined quantitative measures for effectiveness Does not sufficiently emphasize institutional factors |
Borge and Bröring (2017); Bozeman (2000); Bozeman et al. (2015); Smart and Benaroya (2016) |
| Triple Helix Model | To provide guidance for fostering collaboration between universities, industry, and government to enhance innovation outputs that drive economic development | Collaborative interactions among universities, industry, and government drive innovation The generation and cross-pollination of new knowledge drives economic growth The boundaries of the roles between universities, industry, and government evolve Institutional factors moderate the influence of innovation on generating economic development |
Primarily conceptual Reifies the organization construct Some constructs are ambiguous Difficult to measure some constructs of the model Oversimplifies the interactions in real-world innovation ecosystems Ignores certain sociological factors like power dynamics Inadequate consideration of the environment in which universities, governments, and private sector firms operate May not accurately reflect various institutional and cultural contexts such as developing countries Contextual variability limits generalization across contexts |
Cai (2015); Cai and Amaral (2021); Deakin (2022); Leydesdorff and Etzkowitz (1996, 1998) |
| Quadruple Helix Model | To provide guidance for fostering collaboration between universities, industry, government, and society to enhance innovation outputs that drive socially responsible economic development that is sustainable | Collaborative interactions among universities, industry, government, and society drive innovation The generation and cross-pollination of new knowledge drives economic growth Society plays an essential role in shaping innovation The dynamics of innovation likely vary across different contexts Innovation should align with the broader goals of society |
Primarily conceptual Reifies the organization construct Assumptions and premises are not empirically validated to a sufficient degree Additional complexity makes the model difficult to apply The role and influence of society is ambiguous Does not adequately account for certain sociological factors such as power dynamics Core premises embed normative biases |
Afonso et al. (2010); Campanella et al. (2017); Carayannis et al. (2012); Cloitre et al. (2023); König et al. (2020); Kunwar and Ulak (2024); Leydesdorff and Smith (2022); Mineiro et al. (2021); Noya et al. (2024) |
| Quintuple Helix Model | To provide guidance for fostering collaboration between universities, industry, government, society, and the natural environment to enhance innovation outputs that drive socially responsible, ecologically sound economic development that is sustainable | Collaborative interactions among universities, industry, government, society, and the natural environment drive innovation The generation and cross-pollination of new knowledge drives economic growth Society plays an essential role in shaping innovation The natural environment has an integral role in shaping innovation The dynamics of innovation likely vary across different contexts Innovation should align with the broader goals of society |
Primarily conceptual Reifies the organization construct Assumptions and premises are not empirically validated to a sufficient degree Additional complexity makes the model difficult to apply The role and influence of the natural environment is ambiguous Overgeneralizes interactions among the various actors and thus fails to account for contextual differences Core premises embed normative biases |
Carayannis et al. (2012); Carayannis and Campbell (2010); Kunwar and Ulak (2024); Leydesdorff and Smith (2022); Mineiro et al. (2021); Mutlu and Arikboga (2023) |
| Battistella-DeToni-Pillon Model of Technology and Knowledge Transfer | To identify critical factors for technology and knowledge transfer from academia to the private sector and direct future research on the relationships of the identified factors | Mutual understanding and trust between knowledge producers and acquirers are necessary conditions for successful transfer Intermediaries function as bridges between research entities and private sector organizations Contextual factors such as social, economic, and regulatory environments affect the technology transfer process Feedback mechanisms between research entities and private sector organizations support iterative improvements |
Primarily conceptual Reifies the organization construct Lacks empirical validation Difficult to operationalize Oversimplifies the technology transfer process Presents technology transfer as a linear process Does not adequately account for the influence of socio-political contexts Does not adequately account for the influence of organizational factors such as absorptive capacity May not be able to generalize to different industries and geopolitical contexts |
Battistella et al. (2016) |
| Prodan-Drnovsek-Ulijn Model of Technology Transfer |
To help researchers, policy makers, and practitioners design policy and instruments to facilitate the transfer of technology from academia to new business ventures | University technology transfer via new business ventures is primarily driven by faculty involvement Academic entrepreneurs rely on their personal networks to secure necessary resources Technology transfer via faculty involved new business ventures is affected by the nature of the academic’s personal network, the length of their academic career, the nature of the academic’s research, personality-driven motivational factors, entrepreneurial self-efficacy, previous engagement with the private sector, exposure to academic entrepreneurial role models, and institutional support |
Primarily conceptual Overly abstract Lacks empirical validation Focus is only on technology transfer via new business ventures Ignores certain sociological factors like power dynamics Ignores the influence of environmental factors Does not account for potential organizational change May not be able to generalize to different cultural contexts |
Prodan et al. (2009) |
| Respondents | Count True | Count Not True | % True | % Not True | |
| Insufficient maturity is one of several reasons for not licensing | 182 | 89 | 93 | 0.49 | 0.51 |
| Insufficient maturity is the most important reason for not licensing | 175 | 40 | 135 | 0.23 | 0.77 |
| Screening Words | Screening Phrases | |
| feasibility maturity premature readiness underdeveloped undeveloped |
contact me when contact us when current state of development stage discovery project discovery stage early nature of early research stage early stage lack of later stage little early more advanced more advancement more developed once further |
once the once .* validated once .* validation pass on it .* should you pass on it .* should your pass on it .* if proof.of.concept reach out to me when reach out to us when readiness level ready within somewhat early technical challenges technology.readiness too early very early |
| Count | Pct of Total | |
| Total cases with notes about the reason for the solicited company’s disinterest in a technology | 1,665 | 1.0000 |
| Total cases in which insufficient maturity was the reason for the company’s disinterest | 84 | 0.0505 |
| Chain | Quantile | Accuracy | Probability | Estimated Iterations Required | Independent Samples Required |
Dependence Factor |
| 1 | 0.025 | ± 0.005 | 0.95 | 5,810 | 3,746 | 1.55 |
| 2 | 0.025 | ± 0.005 | 0.95 | 5,721 | 3,746 | 1.53 |
| 3 | 0.025 | ± 0.005 | 0.95 | 5,691 | 3,746 | 1.52 |
| 2.5% | 5.0% | 25.0% | 50.0% | 75.0% | 95% | 97.5% |
| 0.1774 | 0.1862 | 0.2146 | 0.2354 | 0.2570 | 0.2894 | 0.3004 |
| Chain | Quantile | Accuracy | Probability | Estimated Iterations Required | Independent Samples Required |
Dependence Factor |
| 1 | 0.025 | ± 0.005 | 0.95 | 5,800 | 3,746 | 1.55 |
| 2 | 0.025 | ± 0.005 | 0.95 | 5,731 | 3,746 | 1.53 |
| 3 | 0.025 | ± 0.005 | 0.95 | 5,880 | 3,746 | 1.57 |
| 2.5% | 5.0% | 25.0% | 50.0% | 75.0% | 95% | 97.5% |
| 0.0409 | 0.0424 | 0.0472 | 0.0507 | 0.0544 | 0.0601 | 0.0620 |
| Theta Parameter | ||||||
| Chain | Quantile | Accuracy | Probability | Estimated Iterations Required | Independent Samples Required |
Dependence Factor |
| 1 | 0.025 | ± 0.005 | 0.95 | 5,581 | 3,746 | 1.49 |
| 2 | 0.025 | ± 0.005 | 0.95 | 5,571 | 3,746 | 1.49 |
| 3 | 0.025 | ± 0.005 | 0.95 | 5,440 | 3,746 | 1.45 |
| Lambda Parameter | ||||||
| Chain | Quantile | Accuracy | Probability | Estimated Iterations Required | Independent Samples Required |
Dependence Factor |
| 1 | 0.025 | ± 0.005 | 0.95 | 3,777 | 3,746 | 1.010 |
| 2 | 0.025 | ± 0.005 | 0.95 | 3,780 | 3,746 | 1.010 |
| 3 | 0.025 | ± 0.005 | 0.95 | 3,742 | 3,746 | 0.999 |
| 2.5% | 5.0% | 25.0% | 50.0% | 75.0% | 95% | 97.5% | |
| Probability of Zero | 0.0449 | 0.0469 | 0.0538 | 0.0589 | 0.0644 | 0.0728 | 0.0757 |
| Revenue Amount | $617,074 | $617,083 | $617,109 | $617,127 | $617,145 | $617,172 | $617,180 |
| Reasons Technologies Declined | ||||||
| Company | Insufficient Maturity | Lack of strategic alignment | Lack of financial capacity | Total Technologies Declined | Pct of Technologies Declined for Insufficient Maturity | Survey Response Indicates Insufficient Maturity is Primary Reason |
| 1 | 8 | 6 | 7 | 21 | 38.10% | 1 |
| 2 | 9 | 8 | 8 | 25 | 36.00% | 1 |
| 3 | 6 | 76 | 68 | 150 | 4.00% | 0 |
| 4 | 5 | 75 | 57 | 137 | 3.65% | 0 |
| 5 | 3 | 83 | 60 | 146 | 2.05% | 0 |
| Totals | 31 | 248 | 200 | 479 | ||
| Overall Percentage of Technologies Declined for Insufficient Maturity | 6.47% | |||||
| Percentage of Survey Responses Indicating Insufficient Maturity is Primary Reason | 40.00% | |||||
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
