PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Non-invasive Brain Stimulation Enhance the Physical Exercise Effect Against the Cognition Impairments and Dementia Symptoms in Alzheimer’s Disease: A Experimental Controlled Trial
Version 1
: Received: 23 May 2024 / Approved: 23 May 2024 / Online: 24 May 2024 (09:38:08 CEST)
How to cite:
Furtado-da-Silva, V.; Borges, C. J.; Freire, I. D. A.; Militão, A. G.; Vieira, M. A. D. M.; Ribeiro, D. E. C.; Ribeiro, D. F. D. C.; Valentim-Silva, J. R. Non-invasive Brain Stimulation Enhance the Physical Exercise Effect Against the Cognition Impairments and Dementia Symptoms in Alzheimer’s Disease: A Experimental Controlled Trial. Preprints2024, 2024051570. https://doi.org/10.20944/preprints202405.1570.v1
Furtado-da-Silva, V.; Borges, C. J.; Freire, I. D. A.; Militão, A. G.; Vieira, M. A. D. M.; Ribeiro, D. E. C.; Ribeiro, D. F. D. C.; Valentim-Silva, J. R. Non-invasive Brain Stimulation Enhance the Physical Exercise Effect Against the Cognition Impairments and Dementia Symptoms in Alzheimer’s Disease: A Experimental Controlled Trial. Preprints 2024, 2024051570. https://doi.org/10.20944/preprints202405.1570.v1
Furtado-da-Silva, V.; Borges, C. J.; Freire, I. D. A.; Militão, A. G.; Vieira, M. A. D. M.; Ribeiro, D. E. C.; Ribeiro, D. F. D. C.; Valentim-Silva, J. R. Non-invasive Brain Stimulation Enhance the Physical Exercise Effect Against the Cognition Impairments and Dementia Symptoms in Alzheimer’s Disease: A Experimental Controlled Trial. Preprints2024, 2024051570. https://doi.org/10.20944/preprints202405.1570.v1
APA Style
Furtado-da-Silva, V., Borges, C. J., Freire, I. D. A., Militão, A. G., Vieira, M. A. D. M., Ribeiro, D. E. C., Ribeiro, D. F. D. C., & Valentim-Silva, J. R. (2024). Non-invasive Brain Stimulation Enhance the Physical Exercise Effect Against the Cognition Impairments and Dementia Symptoms in Alzheimer’s Disease: A Experimental Controlled Trial. Preprints. https://doi.org/10.20944/preprints202405.1570.v1
Chicago/Turabian Style
Furtado-da-Silva, V., Dora Flora de Castro Ribeiro and João Rafael Valentim-Silva. 2024 "Non-invasive Brain Stimulation Enhance the Physical Exercise Effect Against the Cognition Impairments and Dementia Symptoms in Alzheimer’s Disease: A Experimental Controlled Trial" Preprints. https://doi.org/10.20944/preprints202405.1570.v1
Abstract
Background: Alzheimer's Disease (AD) is a progressive and incurable condition that prompts the exploration of interventions to slow its advancement and enhance the quality of life. The cortical brain waves could have a role in the process of executive function deterioration, increasing dementia symptoms. Objective: To interrogate the effects of physical exercise, and non-invasive brain stimulation, both in electrophysiological behavior of the brain, the executive functions, and dementia symptoms in older adults with AD. Methods: One hundred and sixteen older adults were grouped (n=22 each): GAE (AD, PMED+NIBS), GCP (AD, PMED), GCN (AD, NIBS), GCS (control, no intervention). Binaural beats were used as a non-invasive brain stimulation, physical exercise, or both, were applied during 16 weeks. Pre/post measurements included Alpha Band, and SMR Rhythms, executive functions, and dementia symptoms. Results: GCS showed no significant changes (p>0.05). GCN and GCS slightly enhanced inhibitory control (p>0.05) and working memory (p>0.05). In contrast, GCP and GAE improved executive function (p
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
