Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

States of Arts and New Approaches to Spinal Cord Tumors

Version 1 : Received: 21 May 2024 / Approved: 22 May 2024 / Online: 22 May 2024 (14:45:13 CEST)

How to cite: Kumawat, C.; Takahashi, T.; Date, I.; Tomita, Y.; Tanaka, M.; Arataki, S.; Komatubara, T.; Flores, A. O. P.; Yu, D.; Jain, M. States of Arts and New Approaches to Spinal Cord Tumors. Preprints 2024, 2024051441. https://doi.org/10.20944/preprints202405.1441.v1 Kumawat, C.; Takahashi, T.; Date, I.; Tomita, Y.; Tanaka, M.; Arataki, S.; Komatubara, T.; Flores, A. O. P.; Yu, D.; Jain, M. States of Arts and New Approaches to Spinal Cord Tumors. Preprints 2024, 2024051441. https://doi.org/10.20944/preprints202405.1441.v1

Abstract

Spinal cord tumors, though rare, present formidable challenges in clinical management due to their intricate nature. Traditional treatment modalities like surgery, radiation therapy, and chemotherapy have been the mainstay for managing these tumors. However, despite significant advancements, challenges persist, including the limitations of surgical resection and the potential side effects associated with radiation therapy. In response to these limitations, a wave of innovative approaches is reshaping the treatment landscape for spinal cord tumors. Advancements in gene therapy, immunotherapy, and targeted therapy are offering groundbreaking possibilities. Gene therapy holds the potential to modify the genes responsible for tumor growth, while immunotherapy harnesses the body's own immune system to fight cancer cells. Targeted therapy aims to strike a specific vulnerability within the tumor cells, offering a more precise and potentially less toxic approach. Additionally, novel surgical adjuncts are being explored to improve visualization and minimize damage to surrounding healthy tissue during tumor removal. These developments pave the way for a future of personalized medicine for spinal cord tumors. By delving deeper into the molecular makeup of individual tumors, doctors can tailor treatment strategies to target specific mutations and vulnerabilities. This personalized approach offers the potential for more effective interventions with fewer side effects, ultimately leading to improved patient outcomes and a better quality of life. This evolving landscape of spinal cord tumor management signifies the crucial integration of established and innovative strategies to create a brighter future for patients battling this complex condition.

Keywords

spinal cord tumor; astrocytoma; diagnosis; Current treatment; surgery

Subject

Medicine and Pharmacology, Neuroscience and Neurology

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