Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The ‘Radiant Effect’: Recent Sonographic Image-Enhancing Technique and Its Impact on Nuchal Translucency Measurements

Version 1 : Received: 11 May 2024 / Approved: 12 May 2024 / Online: 13 May 2024 (12:15:17 CEST)

How to cite: Bergsch, A.; Degenhardt, J.; Stressig, R.; Dudwiesus, H.; Graupner, O.; Ritgen, J. The ‘Radiant Effect’: Recent Sonographic Image-Enhancing Technique and Its Impact on Nuchal Translucency Measurements. Preprints 2024, 2024050761. https://doi.org/10.20944/preprints202405.0761.v1 Bergsch, A.; Degenhardt, J.; Stressig, R.; Dudwiesus, H.; Graupner, O.; Ritgen, J. The ‘Radiant Effect’: Recent Sonographic Image-Enhancing Technique and Its Impact on Nuchal Translucency Measurements. Preprints 2024, 2024050761. https://doi.org/10.20944/preprints202405.0761.v1

Abstract

Background: This study assesses the effects of the ‘Radiant’ image enhancement technique on fetal nuchal translucency (NT) measurements during first trimester sonographic ex-ams. Methods: A retrospective analysis of 263 ultrasound images of first trimester midsagittal sections was conducted. NT measurements were obtained using a semi-automatic tool. Statistical methods were applied to compare NT measurements with and without ‘Radi-ant’ enhancement. An in-vitro setup with predefined line distances provided additional data. Results: Incremental increases in NT measurements were observed with varying levels of ‘Radiant’ application: An average increase of 0.19 mm with ‘Radiant min’, 0.24 mm with ‘Radiant mid’ and 0.30 mm with ‘Radiant max.’ The in-vitro results supported these findings, showing consistent effects on line thickness and measurement accuracy, with the smallest mean deviation occurring at the ‘Radiant mid’ setting. Conclusions: ‘Radiant’ image enhancement leads to significant increases in NT measure-ments. To avoid systematic biases in clinical assessments, it is advisable to disable ‘Radi-ant’ during NT measurement procedures. Further studies are necessary to corroborate these findings and to consider updates to the NT reference tables based on this technology.

Keywords

Nuchal Translucency; First Trimester Screening; Image Enhancement; Aneuploidies; Prenatal Diagnostics

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

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