PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Impact of Comorbidities and the Duration of Mechanical Venti-Lation on Outcomes of Surgical Patients with Isolated Candida Species in the Intensive Care Unit: A Cross-Sectional Study
Version 1
: Received: 15 April 2024 / Approved: 19 April 2024 / Online: 19 April 2024 (11:44:57 CEST)
How to cite:
Glavaš Tahtler, J.; Kvolik, S. Impact of Comorbidities and the Duration of Mechanical Venti-Lation on Outcomes of Surgical Patients with Isolated Candida Species in the Intensive Care Unit: A Cross-Sectional Study. Preprints2024, 2024041342. https://doi.org/10.20944/preprints202404.1342.v1
Glavaš Tahtler, J.; Kvolik, S. Impact of Comorbidities and the Duration of Mechanical Venti-Lation on Outcomes of Surgical Patients with Isolated Candida Species in the Intensive Care Unit: A Cross-Sectional Study. Preprints 2024, 2024041342. https://doi.org/10.20944/preprints202404.1342.v1
Glavaš Tahtler, J.; Kvolik, S. Impact of Comorbidities and the Duration of Mechanical Venti-Lation on Outcomes of Surgical Patients with Isolated Candida Species in the Intensive Care Unit: A Cross-Sectional Study. Preprints2024, 2024041342. https://doi.org/10.20944/preprints202404.1342.v1
APA Style
Glavaš Tahtler, J., & Kvolik, S. (2024). Impact of Comorbidities and the Duration of Mechanical Venti-Lation on Outcomes of Surgical Patients with Isolated Candida Species in the Intensive Care Unit: A Cross-Sectional Study. Preprints. https://doi.org/10.20944/preprints202404.1342.v1
Chicago/Turabian Style
Glavaš Tahtler, J. and Slavica Kvolik. 2024 "Impact of Comorbidities and the Duration of Mechanical Venti-Lation on Outcomes of Surgical Patients with Isolated Candida Species in the Intensive Care Unit: A Cross-Sectional Study" Preprints. https://doi.org/10.20944/preprints202404.1342.v1
Abstract
Abstract: Comorbidities of patients may be related to the duration of mechanical ventilation, survival, and Candida isolation during intensive care unit (ICU) stay. To examine the frequency of Candida isolation and significant comorbidities in the surgical intensive care unit (ICU) in Osijek University Hospital, Croatia, the data from the electronic database from May 2016 to June 30, 2023, were analyzed. In a cross-sectional study examining 15,790 microbiological samples, different strains of Candida were observed in 581 samples from 236 patients. The control group was 160 consecutive patients from March-May 2019, and 161 in the same months of 2020 (pre- and post-COVID-19). Comorbidities, duration of mechanical ventilation and survival were compared. Patients with isolated Candida were more often non-elective, had significantly more heart, kidney, liver diseases and sepsis (P<0.001). The duration of mechanical ventilation was 9.2 [2.2-9.24], 96 [24-146], 160 [19.5-343] and 224 [73.5-510] hours in controls, and patients with Candida albicans, non-albicans, and in patients with ³2 Candidas isolated. The mortality was significantly higher and reached 42% in patients with Candida isolated, while in the control group, it was 19% (P<0.001). In a multivariate analysis adjusted for patient’s age, SAPS II score, days of ICU, and type of admission, only sepsis was independent predictor of mortality (OR = 2.27).
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
