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16 April 2024
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17 April 2024
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Familiar name | Tissue distribution | HGNC | Type | Has Tunicate ortholog ? |
Cadherin E | Epithelial | CDH1 | I | Yes |
Cadherin N | Neural | CDH2 | I | Yes |
Cadherin P | Placental | CDH3 | I | |
Cadherin R | Retinal | CDH4 | I | |
Cadherin VE | Epithelial | CDH5 | II | |
Cadherin K | Brain; kidney | CDH6 | II | |
Cadherin OB | Osteoblast | CDH11 | II | Yes |
Cadherin BR | Brain | CDH12 | II | |
Cadherin T and H | Heart | CDH13 | I | |
Cadherin M | Muscle | CDH15 | I |
HGNC | Steps | equal to mode | HGNC | Steps | equal to mode | |
ADGRL3 | 3.15 | 4 | MGAT4D | 4.08 | 4 | |
ANKRD16 | 4.77 | 4 | MSMP | 1.15 | 6 | |
ANKRD42 | 2.38 | 8 | MUM1 | 2.10 | 5 | |
ARHGEF38 | 2.67 | 4 | MYBPC3 | 2.08 | 6 | |
ASB2 | 3.92 | 5 | MYL5 | 5.01 | 3 | |
ATRAID | 0.46 | 11 | NEBL | 2.16 | 6 | |
BCL6B | 2.95 | 4 | NECTIN3 | 1.85 | 4 | |
C18ORF21 | 0.62 | 9 | NEXN | 2.46 | 5 | |
CALML6 | 2.47 | 8 | NPC1L1 | 4.85 | 5 | |
CASR | 1.92 | 7 | OLFML2A | 1.54 | 5 | |
CATIP | 3.18 | 4 | OTULIN | 1.55 | 7 | |
CBLN1 | 1.38 | 4 | PDX1 | 2.77 | 4 | |
CCDC78 | 2.62 | 4 | PHF21A | 2.46 | 4 | |
CEP63 | 3.40 | 5 | PODN | 3.46 | 4 | |
CEP83 | 2.46 | 7 | PRR14 | 2.27 | 6 | |
CKAP2 | 2.54 | 5 | RBM14 | 3.61 | 3 | |
CLDN1 | 0.83 | 7 | RHBDL2 | 4.54 | 4 | |
CLDN18 | 1.25 | 5 | RNF4 | 4.85 | 3 | |
CLDN19 | 0.92 | 7 | SCLT1 | 3.18 | 6 | |
CLDN7 | 1.23 | 6 | SERINC5 | 4.38 | 5 | |
EFNA1 | 1.92 | 4 | SLC35G2 | 3.31 | 4 | |
FABP2 | 1.00 | 8 | SLC35G3 | 4.86 | 3 | |
FAM155B | 1.54 | 5 | SLC35G4 | 5.13 | 3 | |
FAM187A | 1.23 | 6 | SLC35G5 | 5.50 | 3 | |
FAM3D | 2.38 | 4 | SLC35G6 | 4.25 | 4 | |
FBXO24 | 2.23 | 6 | SLC6A14 | 3.54 | 3 | |
FOXH1 | 2.95 | 5 | SLC6A6 | 3.46 | 4 | |
GJA10 | 2.02 | 5 | SNRNP48 | 2.31 | 8 | |
GJA3 | 1.16 | 7 | SPATA21 | 4.50 | 3 | |
GJC2 | 2.38 | 6 | STXBP6 | 1.77 | 8 | |
GNA15 | 4.00 | 3 | TGFB1 | 2.15 | 4 | |
GTF2IRD2 | 3.00 | 3 | TGFB2 | 1.54 | 6 | |
GTF2IRD2B | 4.30 | 3 | TLCD2 | 3.62 | 3 | |
GVQW1 | 4.05 | 2 | TMEM218 | 0.62 | 9 | |
H1FOO | 3.23 | 3 | TNNC1 | 4.08 | 6 | |
HMMR | 2.92 | 8 | TNNC2 | 4.08 | 4 | |
HNF1A | 1.15 | 7 | TSPAN12 | 2.69 | 5 | |
HSPB1 | 3.23 | 3 | WSB1 | 2.31 | 4 | |
IKZF5 | 2.85 | 5 | ZBED5 | 2.46 | 4 | |
IL17C | 1.78 | 4 | ZBED8 | 2.83 | 4 | |
KIZ | 1.23 | 6 | ZC3H7B | 1.38 | 8 | |
LRRC29 | 3.09 | 4 | ZNF91 | 4.88 | 2 |
HGNC | Unique ID * | Uniprot | Expect value ** |
MYBPC1 | Cirobu.g00000146 | Q00872 | 0 |
MYBPC2 | Cirobu.g00000146 | Q14324 | 0 |
MYBPC3 | Cirobu.g00000146 | Q14896 | 0 |
MYH1 | Boschl.g00071919 | P12882 | 0 as myosin heavy chain, cardiac muscle isoform Ciona intestinalis |
MYH13 | Harore.g00014293 | Q9UKX3 | 0 as embryonic muscle myosin heavy chain Halocynthia roretzi |
MYH15 | Harore.g00003537 | Q9Y2K3 | 0 as embryonic muscle myosin heavy chain Halocynthia roretzi |
MYH4 | Cirobu.g00005587 | Q9Y623 | 0 as myosin heavy chain, cardiac muscle isoform Ciona intestinalis |
MYH8 | Harore.g00010698 | P13535 | 0 as embryonic muscle myosin heavy chain Halocynthia roretzi |
MYL4 | Cirobu.g00008856 | P12829 | 2E-74 as smooth muscle isoform X3 of Ciona intestinalis |
MYL5 | Cirobu.g00008931 | Q02045 | 2.00E-82 |
MYL7 | Cirobu.g00009534 | Q01449 | 3E-73 as smooth muscle isoform X1 of Ciona intestinalis |
MYOM1 | Phmamm.g00001992 | P52179 | 7.00E-93 |
MYBPC1 | Cirobu.g00000146 | Q00872 | 0 |
MYBPC2 | Cirobu.g00000146 | Q14324 | 0 |
MYBPC3 | Cirobu.g00000146 | Q14896 | 0 |
PALLD | Cirobu.g00008036 | Q8WX93 | 1.00E-109 |
SYNPO2 | Boleac.g00003200 | Q9UMS6 | 2.00E-13 |
TNNT1 | Cirobu.g00006671 | P13805 | 8E-85 as TroponinT, slow skletal muscle of Ciona intestinalis |
HGNC Symbol | Uniprot Symbol | Expect Value * | XP_026690575.1 |
GJA4 | P35212 | 4.00E-41 | XP_002119855.2 |
GJA5 | P36382 | 1.00E-32 | XP_004227068.2 |
GJA8 | P48165 | 3.00E-57 | CAB3249107.1 |
GJB1 | P08034 | 6.00E-34 | CAB3249120.1 |
GJB2 | P29033 | 7.00E-35 | XP_026696017.1 |
GJB6 | O95452 | 3.00E-47 | XP_002130872.1 |
GJC1 | P36383 | 3.00E-67 | XP_026691633.1 |
* The Expect values were from 2-sequence BLAST analyses against the corresponding human homolog | ** from BLAST search. Click to retrieve the FASTA sequence |
Ephron Genes | Ephrin Genes | ||
HGNC symbol | Latest ortholog in: | HGNC symbol | Latest ortholog in: |
EPHA2 | Tunicata | EFNA1 | Tunicata |
EPHA3 | Elasmobranchii | EFNA2 | Tunicata |
EPHA4 | Tunicata | EFNA3 | Tunicata |
EPHA5 | Branchiostomata | EFNA4 | Tunicata |
EPHA6 | Elasmobranchii | EFNA5 | Tunicata |
EPHA7 | Elasmobranchii | EFNB1 | Tunicata |
EPHA8 | Elasmobranchii | EFNB2 | Branchiostomato |
EPHA10 | Osteichthyes | EFNB3 | Elasmobranchii |
EPHB2 | Branchiostomata | ||
EPHB3 | Elasmobranchii | ||
EPHB4 | Cnidaria |
Term | Genes | FDR * | |
Cluster 2 | |||
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | NECTIN3, CBLN1, NECTIN1 | 0.358759 | |
identical protein binding | TFAP2E, COL23A1, HSPB1, NECTIN3, CBLN1, NECTIN1 | 0.671885 | |
Cluster 4 | Synapse | NECTIN3, CBLN1, NECTIN1 | 0.935728 |
homophilic cell adhesion via plasma membrane adhesion molecules | PALLD, NECTIN3, NECTIN1 | 0.739434 | |
DOMAIN:Ig-like C2-type 1 | PALLD, NECTIN3, NECTIN1 | 0.656496 | |
DOMAIN:Ig-like C2-type 2 | PALLD, NECTIN3, NECTIN1 | 0.656496 | |
Immunoglobulin domain | PALLD, NECTIN3, NECTIN1 | 0.877976 | |
Immunoglobulin-like fold | PALLD, NECTIN3, NECTIN1 | 0.984375 | |
Cluster 6 | |||
Z disc | PALLD, SYNPO2, HSPB1 | 0.481232 | |
actin cytoskeleton | CALD1, PALLD, SYNPO2 | 0.564483 | |
actin binding | CALD1, PALLD, SYNPO2 | 0.614614 | |
focal adhesion | PALLD, SYNPO2, HSPB1 | 0.679141 | |
Cluster 7 | |||
Signaling pathways regulating pluripotency of stem cells | FZD3, ZIC3, FZD6 | 0.180791 | |
Developmental protein | FZD3, ZIC3, FZD6, PITX3 | 0.819281 | |
Cluster 8 | |||
Zinc | ZMAT1, ZIC3, ASXL3 | 1 | |
Zinc-finger | ZMAT1, ZIC3, ASXL3 | 0.988184 | |
Metal-binding | ZMAT1, ZIC3, ASXL3 | 1 |
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