Version 1
: Received: 4 April 2024 / Approved: 4 April 2024 / Online: 4 April 2024 (11:00:58 CEST)
How to cite:
Torres, A. D. U.; Sarrouh, B.; Lofrano, R. C. Z. Preliminary Evaluation of Poly-(Sorbitol-Co-Citrate Adipate) Properties for Application as Biomaterial. Preprints2024, 2024040369. https://doi.org/10.20944/preprints202404.0369.v1
Torres, A. D. U.; Sarrouh, B.; Lofrano, R. C. Z. Preliminary Evaluation of Poly-(Sorbitol-Co-Citrate Adipate) Properties for Application as Biomaterial. Preprints 2024, 2024040369. https://doi.org/10.20944/preprints202404.0369.v1
Torres, A. D. U.; Sarrouh, B.; Lofrano, R. C. Z. Preliminary Evaluation of Poly-(Sorbitol-Co-Citrate Adipate) Properties for Application as Biomaterial. Preprints2024, 2024040369. https://doi.org/10.20944/preprints202404.0369.v1
APA Style
Torres, A. D. U., Sarrouh, B., & Lofrano, R. C. Z. (2024). Preliminary Evaluation of Poly-(Sorbitol-Co-Citrate Adipate) Properties for Application as Biomaterial. Preprints. https://doi.org/10.20944/preprints202404.0369.v1
Chicago/Turabian Style
Torres, A. D. U., Boutros Sarrouh and Renata Carolina Zanetti Lofrano. 2024 "Preliminary Evaluation of Poly-(Sorbitol-Co-Citrate Adipate) Properties for Application as Biomaterial" Preprints. https://doi.org/10.20944/preprints202404.0369.v1
Abstract
This study evaluated the stability of the Poly-(sorbitol-co-citrate adipate) with potential applica-tion in the biomedical area. Thus, the physical, chemical and microbiological stability of this was investigated. First, the chemical stability in alkaline phosphate buffer (pH 7.4) was evaluated for 5 days. In aqueous solution, the copolymer acidified the medium indicating the presence of residual citric acid. In the moisture absorption test the results obtained followed the pH, reinforcing the presence of citric acid. In the evaluation of the antimicrobial activity the results indicate that the copolymer did not allow the growth of the yeast Saccharomyces cerevisiae, as the only source of carbon. However, in the cell lysis phase and due to the restriction of access to nutrients in the culture medium, the copolymer showed a loss of mass due to its use by the microorganism. Thus, it presented biodegradability property under extreme conditions of cell culture.
Chemistry and Materials Science, Polymers and Plastics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
