Essay
Version 1
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A Mathematical Model of Disease
Version 1
: Received: 2 April 2024 / Approved: 3 April 2024 / Online: 4 April 2024 (15:55:52 CEST)
How to cite: Schnitzler, M. A Mathematical Model of Disease. Preprints 2024, 2024040313. https://doi.org/10.20944/preprints202404.0313.v1 Schnitzler, M. A Mathematical Model of Disease. Preprints 2024, 2024040313. https://doi.org/10.20944/preprints202404.0313.v1
Abstract
The identification of fetal cells in the blood and tissues of healthy mothers raised questions about the potential alloreactive origins of various diseases, such as autoimmunity, diabetes, arteriosclerosis, and cancer. However, the extent to which alloreactivity contributes to these diseases remains unverified. This study presents a basic mathematical disease model based on the genes’ origin and immunological interactions. This model, grounded in set theory, classifies these immunological interactions based on their intrinsic, extrinsic, and allogeneic nature. Therefore, this model offers an unexpected common theoretical foundation for understanding alloreactivity, genetic diseases, and infections. Furthermore, this model provides a valuable framework for scrutinizing the role of alloreactivity in health and disease.
Keywords
alloreactivity; fetal microchimerism; relativity; set theory; non-communicable diseases; autoimmunity; diabetes; arteriosclerosis; cancer
Subject
Medicine and Pharmacology, Transplantation
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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