Moraes da Silva Junior, S.; Bento Ribeiro, L.E.; Fruett, F.; Stiens, J.; Willibrordus Swart, J.; Moshkalev, S. A Novel Microfluidics Droplet-Based Interdigitated Ring-Shaped Electrode Sensor for Lab-on-a-Chip Applications. Preprints2024, 2024040289. https://doi.org/10.20944/preprints202404.0289.v1
APA Style
Moraes da Silva Junior, S., Bento Ribeiro, L.E., Fruett, F., Stiens, J., Willibrordus Swart, J., & Moshkalev, S. (2024). A Novel Microfluidics Droplet-Based Interdigitated Ring-Shaped Electrode Sensor for Lab-on-a-Chip Applications. Preprints. https://doi.org/10.20944/preprints202404.0289.v1
Chicago/Turabian Style
Moraes da Silva Junior, S., Jacobus Willibrordus Swart and Stanislav Moshkalev. 2024 "A Novel Microfluidics Droplet-Based Interdigitated Ring-Shaped Electrode Sensor for Lab-on-a-Chip Applications" Preprints. https://doi.org/10.20944/preprints202404.0289.v1
Abstract
Droplet-based microfluidics has revolutionized numerous fields such as biomedical research, pharmaceuticals, drug discovery, food engineering, flow chemistry, and cosmetics. This paper presents a comprehensive study focusing on the detection and characterization of droplets with volumes in the nanoliter range. Leveraging the precise control of minute liquid volumes, we introduced a novel spectroscopic On-Chip microsensor equipped with integrated microfluidic channels for droplet generation, characterization, and sensing, simultaneously. The microsensor, designed with Interdigitated-Ring-Shaped Electrodes (IRSE) and seamlessly integrated with microfluidic channels, offers enhanced capacitance and impedance signal amplitudes, reproducibility, and reliability in droplet analysis. We were able to make analyses of droplets length in the range 1.0-6.0 mm, velocity 0.66-2.51 mm/s, droplet volume 1.07nL-113.46nL. Experimental results demonstrated that the microsensor's has a great performance in terms of droplet size, velocity, and length, with a significant signal amplitude of capacitance and impedance, and real-time detection capabilities, thereby highlighting its potential for facilitating microcapsule reactions and enabling on-site real-time detection for chemical and biosensor analyses on-chip.
Engineering, Electrical and Electronic Engineering
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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