Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Dietary Intake and Oral Glucose Tolerance Test Results in Women with Gestational Diabetes

Version 1 : Received: 2 April 2024 / Approved: 3 April 2024 / Online: 3 April 2024 (08:20:34 CEST)

How to cite: das Chagas, L.A.; Torloni, M.R.; Silva-Neto, L.G.R.; Dualib, P.M.; de Sousa, R.M.L.; Bittencourt, J.A.S.; Araujo Júnior, E.; Granese, R.; Mattar, R. Dietary Intake and Oral Glucose Tolerance Test Results in Women with Gestational Diabetes. Preprints 2024, 2024040264. https://doi.org/10.20944/preprints202404.0264.v1 das Chagas, L.A.; Torloni, M.R.; Silva-Neto, L.G.R.; Dualib, P.M.; de Sousa, R.M.L.; Bittencourt, J.A.S.; Araujo Júnior, E.; Granese, R.; Mattar, R. Dietary Intake and Oral Glucose Tolerance Test Results in Women with Gestational Diabetes. Preprints 2024, 2024040264. https://doi.org/10.20944/preprints202404.0264.v1

Abstract

Background: Diet is a risk factor for gestational diabetes mellitus (GDM). There are few studies on women´s diet and glucose tolerance test (GTT) results. Objective: To evaluate the relationship between previous diet and the number of abnormal values on the diagnostic GTT in women with GDM. We hypothesized there would be an inverse relation between antioxidant micronutrient consumption and the number of abnormal GTT values. Methods: This cross-sectional study included 60 women diagnosed with GDM (2-hours, 75g-GTT). Shortly after diagnosis, participants answered a validated food frequency questionnaire to assess food consumption in the last 6 months. Mann-Whitney´s test was used to compare the dietary intake of participants with one (group 1) versus two-three (group 2) abnormal GTT values. Results: Participant characteristics were similar. There were no significant differences between groups in median intake of total calories, carbohydrates, lipids and proteins. Participants in group 1 had significantly higher intakes of fiber (11.9 vs. 11.0 g/day p= 0.049), vitamin D (40.6 vs. 40.4 mcg/day p= 0.049) and vitamin C (180.0 vs. 151.0 mg/day p= 0.008) than those in group 2. Conclusion: Results suggest a possible association between consumption of fiber and some antioxidant micronutrients and GDM severity at the time of diagnosis.

Keywords

gestational diabetes mellitus; diet; glucose tolerance test

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

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