Spellicy, S., Baker, E., Arscott, K., Savitz, S., & Stice, S.L. (2024). Reduced Acute Ischemic Stroke-Induced Neural Inflammation Using Neural Stem Cell-Derived Extracellular Vesicles (AB126). Preprints. https://doi.org/10.20944/preprints202404.0216.v1
Chicago/Turabian Style
Spellicy, S., Sean Savitz and Steven L. Stice. 2024 "Reduced Acute Ischemic Stroke-Induced Neural Inflammation Using Neural Stem Cell-Derived Extracellular Vesicles (AB126)" Preprints. https://doi.org/10.20944/preprints202404.0216.v1
Abstract
The therapeutic, attenuative, and morphological effects of proprietary neural stem cell-derived extracellular vesicles (NSC EVs, AB126) produced by Aruna Bio, Inc. were assessed in a range of in vitro and in vivo models of stroke. We emphasize that modulation of neuroinflammation is a key target and suggest further studies to advance our understanding of the mechanisms of action and ultimately how best to dose and monitor the benefits of AB126 in stroke patients.
Medicine and Pharmacology, Neuroscience and Neurology
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