Version 1
: Received: 27 March 2024 / Approved: 28 March 2024 / Online: 28 March 2024 (13:29:35 CET)
How to cite:
Benjamin, C.; Crews, R. Nicotinamide Mononucleotide: Deciphering Metabolic Complexities for Improved Health Outcomes. Preprints2024, 2024031752. https://doi.org/10.20944/preprints202403.1752.v1
Benjamin, C.; Crews, R. Nicotinamide Mononucleotide: Deciphering Metabolic Complexities for Improved Health Outcomes. Preprints 2024, 2024031752. https://doi.org/10.20944/preprints202403.1752.v1
Benjamin, C.; Crews, R. Nicotinamide Mononucleotide: Deciphering Metabolic Complexities for Improved Health Outcomes. Preprints2024, 2024031752. https://doi.org/10.20944/preprints202403.1752.v1
APA Style
Benjamin, C., & Crews, R. (2024). Nicotinamide Mononucleotide: Deciphering Metabolic Complexities for Improved Health Outcomes. Preprints. https://doi.org/10.20944/preprints202403.1752.v1
Chicago/Turabian Style
Benjamin, C. and Rebecca Crews. 2024 "Nicotinamide Mononucleotide: Deciphering Metabolic Complexities for Improved Health Outcomes" Preprints. https://doi.org/10.20944/preprints202403.1752.v1
Abstract
Nicotinamide mononucleotide (NMN), a key NAD+ precursor, exhibits distinct metabolic characteristics and potential health benefits. Recent investigations underscore the pivotal role of gut bacteria and specialized uptake mechanisms in NMN metabolism. While human trials demonstrate NMN's safety and promising health outcomes, challenges persist. Variability in results is likely influenced by lifestyle, health conditions, and individual genetic and gut microbiota differences. Understanding how these factors affect NMN metabolism is crucial for personalized approaches and maximizing NMN's potential. Advances in delivery systems show promise for enhancing NMN bioavailability, but further understanding of optimal NAD+ levels and reliable measures of NMN's effects is necessary. This comprehensive approach is key to optimizing NMN's impact on human health and longevity.
Keywords
nicotinamide mononucleotide; NAD+; vitamin B3; human longevity; bioavailability
Subject
Biology and Life Sciences, Aging
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
