Version 1
: Received: 25 March 2024 / Approved: 26 March 2024 / Online: 26 March 2024 (14:23:26 CET)
How to cite:
Möller, D.F.; Mohorko, B.; Aschauer, T.E.; Schwager, T.; Aschauer, M.A. Retrospective Correlation of the Circulation Time of Test Bolus Injections in MR Angiography and Cardiac Function. Preprints2024, 2024031609. https://doi.org/10.20944/preprints202403.1609.v1
Möller, D.F.; Mohorko, B.; Aschauer, T.E.; Schwager, T.; Aschauer, M.A. Retrospective Correlation of the Circulation Time of Test Bolus Injections in MR Angiography and Cardiac Function. Preprints 2024, 2024031609. https://doi.org/10.20944/preprints202403.1609.v1
Möller, D.F.; Mohorko, B.; Aschauer, T.E.; Schwager, T.; Aschauer, M.A. Retrospective Correlation of the Circulation Time of Test Bolus Injections in MR Angiography and Cardiac Function. Preprints2024, 2024031609. https://doi.org/10.20944/preprints202403.1609.v1
APA Style
Möller, D.F., Mohorko, B., Aschauer, T.E., Schwager, T., & Aschauer, M.A. (2024). Retrospective Correlation of the Circulation Time of Test Bolus Injections in MR Angiography and Cardiac Function. Preprints. https://doi.org/10.20944/preprints202403.1609.v1
Chicago/Turabian Style
Möller, D.F., Tobias Schwager and Manuela Adelinde Aschauer. 2024 "Retrospective Correlation of the Circulation Time of Test Bolus Injections in MR Angiography and Cardiac Function" Preprints. https://doi.org/10.20944/preprints202403.1609.v1
Abstract
This retrospective study examines 248 test-bolus examinations preceding contrast-enhanced magnetic resonance angiography (CE-MRA) to extract clinically relevant data for critical limb ischemia (CLI) management. Methods involved a retrospective review of test-bolus exams, analysing 60 graphs for time-to-peak (TTP), full-width half-maximum (FWHM) time, and time to continual rise in signal intensity. These values were correlated with heart function parameters (ejection fraction, ASA-Classification, Lee-Index, and MET-Score). Results indicate a mean TTP of 31.2 ± 7.3s, showing a correlation between ejection fraction and ASA classification. Patients with atrial fibrillation exhibited prolonged TTP compared to those without. Despite population heterogeneity, findings facilitate risk stratification for limb-saving interventions in CLI. TTP emerges as a potential clinical cardiovascular parameter and a risk factor for vascular interventions. Given the variation in injection protocols across centres, this study underscores the importance of precise bolus arrival time documentation for future multicentre studies.
Keywords
test-bolus examination; magnetic resonance angiography; time-to-peak; peripheral arterial disease
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
