Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Interpreting Diastolic Dynamics and Evaluation Through Echocardiography

Version 1 : Received: 15 March 2024 / Approved: 15 March 2024 / Online: 18 March 2024 (10:09:07 CET)
Version 2 : Received: 30 May 2024 / Approved: 31 May 2024 / Online: 31 May 2024 (12:25:16 CEST)

How to cite: Zhang, X.; Li, K.; Cardoso, C.; Moctezuma-Ramirez, A.; Elgalad, A. Interpreting Diastolic Dynamics and Evaluation Through Echocardiography. Preprints 2024, 2024030952. https://doi.org/10.20944/preprints202403.0952.v1 Zhang, X.; Li, K.; Cardoso, C.; Moctezuma-Ramirez, A.; Elgalad, A. Interpreting Diastolic Dynamics and Evaluation Through Echocardiography. Preprints 2024, 2024030952. https://doi.org/10.20944/preprints202403.0952.v1

Abstract

In patients with heart failure, the evaluation of left ventricular (LV) diastolic function is vital, offering crucial insights into hemodynamic impact and prognostic accuracy. Echocardiography stands as the primary imaging modality for diastolic function assessment, and using it effectively requires a profound understanding of the underlying pathology. This review covers four main topics: first, the fundamental driving forces behind each phase of normal diastolic dynamics, along with the physiological basis of two widely used echocardiographic assessment parameters, E/e' and mitral annulus early diastolic velocity (e'); second, the intricate functional relationship between the left atrium and LV in patients with varying degrees of LV diastolic dysfunction (LVDD); third, the role of stress echocardiography in diagnosing LVDD and the significance of parameter changes in this context; and fourth, the clinical utility of evaluating diastolic function from echocardiography images across diverse cardiovascular care areas.

Keywords

diastolic dynamics; echocardiography evaluation; diastolic dysfunction; stress echocardiography; strain imaging; integrating artificial intelligence

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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