PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Comparison of Propofol and Alfaxalone as Anesthesic Drugs in Bitches Undergoing Ovariohysterectomies (Health Bitches and with Pyometra) and Cesarean Sections
Version 1
: Received: 5 March 2024 / Approved: 5 March 2024 / Online: 6 March 2024 (07:30:00 CET)
How to cite:
Rodríguez-Trujillo, R.; Batista-Arteaga, M.; Iusupova, K.; Rosario-Medina, I.; Alamo-Santana, D. Comparison of Propofol and Alfaxalone as Anesthesic Drugs in Bitches Undergoing Ovariohysterectomies (Health Bitches and with Pyometra) and Cesarean Sections. Preprints2024, 2024030281. https://doi.org/10.20944/preprints202403.0281.v1
Rodríguez-Trujillo, R.; Batista-Arteaga, M.; Iusupova, K.; Rosario-Medina, I.; Alamo-Santana, D. Comparison of Propofol and Alfaxalone as Anesthesic Drugs in Bitches Undergoing Ovariohysterectomies (Health Bitches and with Pyometra) and Cesarean Sections. Preprints 2024, 2024030281. https://doi.org/10.20944/preprints202403.0281.v1
Rodríguez-Trujillo, R.; Batista-Arteaga, M.; Iusupova, K.; Rosario-Medina, I.; Alamo-Santana, D. Comparison of Propofol and Alfaxalone as Anesthesic Drugs in Bitches Undergoing Ovariohysterectomies (Health Bitches and with Pyometra) and Cesarean Sections. Preprints2024, 2024030281. https://doi.org/10.20944/preprints202403.0281.v1
APA Style
Rodríguez-Trujillo, R., Batista-Arteaga, M., Iusupova, K., Rosario-Medina, I., & Alamo-Santana, D. (2024). Comparison of Propofol and Alfaxalone as Anesthesic Drugs in Bitches Undergoing Ovariohysterectomies (Health Bitches and with Pyometra) and Cesarean Sections. Preprints. https://doi.org/10.20944/preprints202403.0281.v1
Chicago/Turabian Style
Rodríguez-Trujillo, R., Inmaculada Rosario-Medina and Desirée Alamo-Santana. 2024 "Comparison of Propofol and Alfaxalone as Anesthesic Drugs in Bitches Undergoing Ovariohysterectomies (Health Bitches and with Pyometra) and Cesarean Sections" Preprints. https://doi.org/10.20944/preprints202403.0281.v1
Abstract
This study compared the efficacy of alfaxalone and propofol to induce anesthesia in bitches undergoing an ovariohysterectomy or cesarean sections. 34 healthy and pyometra-affected females were induced with IV propofol administration, 35 healthy and pyometra-affected bitches were induced with the IV administration of alfaxalone. For the cesarean sections, females were induced with propofol (n=14) or alfaxalone (n=14). Maternal physiological parameters (heart rate, blood pressure, temperature) were recorded throughout surgeries; the viability and a modified Apgar score was recorded in the neonates at 5, 60 and 120 minutes after delivery. The use of propofol and alfaxalone did not show relevant differences over parameters assessed, when ovariohysterectomy was performed in healthy bitches or females with pyometra, as well as when cesarean sections were compared; only, a transient tachycardia appeared after alfaxalone administration. However, a higher percentage of bitches needed extra-doses of propofol. Neonatal mortality was similar between both groups, but when alfaxalone was used a higher neonatal viability was observed. Propofol and alfaxalone showed similar efficacy to perform the ovariohysterectomy in all bitches. Both protocols were optimal for cesarean sections, but alfaxalone was associated with a higher neonatal viability and a higher neonatal survival rate.
Keywords
propofol; alfaxalone; ovariohysterectomy; cesarean section; Apgar test
Subject
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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