Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Antimicrobial resistance burden in India and Germany in 2022: A systematic analysis along with One Health perspective

Version 1 : Received: 21 February 2024 / Approved: 22 February 2024 / Online: 23 February 2024 (09:10:09 CET)

How to cite: K, G.; Pandey, R.P.; K, H.; Mukerjee, R.; Chang, C. Antimicrobial resistance burden in India and Germany in 2022: A systematic analysis along with One Health perspective. Preprints 2024, 2024021334. https://doi.org/10.20944/preprints202402.1334.v1 K, G.; Pandey, R.P.; K, H.; Mukerjee, R.; Chang, C. Antimicrobial resistance burden in India and Germany in 2022: A systematic analysis along with One Health perspective. Preprints 2024, 2024021334. https://doi.org/10.20944/preprints202402.1334.v1

Abstract

Globally increasing antibiotic resistance has been connected to the use of antibiotics in medical, veterinary, and agricultural medicine, contributing to the burden of antibiotic resistance in Asia and Europe. The main objective of this study was to correlations of antimicrobial-resistant of various pathogens in three compartments: humans, animals and the environment in India and Germany. A systematic search was carried out in Medline via PubMed, Google Scholar, and science direct, including studies published in 2022. Out of 532 papers, 24 were considered for meta-analysis. This study reveals that in India, β-lactam is highly resistant in animals. Quinolone, on the other hand, was highly resistant in humans. Furthermore, in the environment and integrated studies, aminoglycosides and β-lactams is resistant. While in Germany, a high rate of AMR resistance in all three sectors was reported in β-lactam. However, E. coli was the most frequent pathogen in both countries and is highly resistant to β-lactam, followed by cephalosporin in all the compartments. Monitoring and evaluating antibiotic-sensitivity patterns and developing proper antibiotic regimens may lead to improved outcomes for inhibiting and controlling E. coli infections in various parts of the world.

Keywords

Antibiotics, Antimicrobial resistance, One Health, Systematic review, India, Germany

Subject

Biology and Life Sciences, Life Sciences

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