Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Association between Blood Lead Levels and Silent Myocardial Infarction in the General Population.

Version 1 : Received: 18 February 2024 / Approved: 21 February 2024 / Online: 22 February 2024 (04:02:48 CET)

A peer-reviewed article of this Preprint also exists.

Mostafa, M.A.; Abueissa, M.A.; Soliman, M.Z.; Ahmad, M.I.; Soliman, E.Z. Association between Blood Lead Levels and Silent Myocardial Infarction in the General Population. J. Clin. Med. 2024, 13, 1582. Mostafa, M.A.; Abueissa, M.A.; Soliman, M.Z.; Ahmad, M.I.; Soliman, E.Z. Association between Blood Lead Levels and Silent Myocardial Infarction in the General Population. J. Clin. Med. 2024, 13, 1582.

Abstract

Background: Although the link between environmental lead exposure and several patterns of cardiovascular disease (CVD) has been reported, its association with silent myocardial infarc-tion (SMI) has not been explored. We aimed to assess the association between blood lead levels (BLL) and risk of SMI. Methods: This analysis included 7283 (mean age 56.1±2.52 years, 52.5% women) participants from the Third National Health and Nutrition Examination Survey who were free of clinical CVD. Ascertainment of BLL done using graphite furnace atomic absorption spectrophotometry. SMI defined as ECG evidence of MI without history of MI. Multivariable lo-gistic regression analysis was used to examine the association between SMI and BLL. Results: SMI was detected in 120 participants corresponding to an unweighted prevalence of 1.65%. Par-ticipants with higher levels of BLL had higher prevalence of SMI (0.4%, 0.9%, and 2.4% across BLL tertiles; p-value

Keywords

Silent Myocardial Infarction; Lead Exposure; Cardiovascular Disease; NHANES-III

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.