Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Poroid Neoplasms: A Clinicopathological Study of 13 Cases

Boubacar Efared
* ORCID logo ,
Idrissa Boubacar
,
Kadre Alio Ousmane Kadre
,
Aichatou Balaraba Abani Bako
,
Hamadou Halidou Koura
,
Habiba Salifou Boureima
,
Idrissa Seriba Coulibaly
,
Soumaila Amadou
,
Hassan Nouhou
Version 1 : Received: 14 February 2024 / Approved: 14 February 2024 / Online: 14 February 2024 (10:59:21 CET)

How to cite: Efared, B.; Boubacar, I.; Ousmane Kadre, K.A.; Bako, A.B.A.; Koura, H.H.; Boureima, H.S.; Coulibaly, I.S.; Amadou, S.; Nouhou, H. Poroid Neoplasms: A Clinicopathological Study of 13 Cases. Preprints 2024, 2024020792. https://doi.org/10.20944/preprints202402.0792.v1 Efared, B.; Boubacar, I.; Ousmane Kadre, K.A.; Bako, A.B.A.; Koura, H.H.; Boureima, H.S.; Coulibaly, I.S.; Amadou, S.; Nouhou, H. Poroid Neoplasms: A Clinicopathological Study of 13 Cases. Preprints 2024, 2024020792. https://doi.org/10.20944/preprints202402.0792.v1

Abstract

Background: Poroid neoplasms (PN) are a heterogeneous group of tumors deriving from sweat glands and folliculo-sebaceous units. Their histological classification and clinical features are challenging. Our aim was to report clinicopathological features of poroid neoplasms. Methods: it is a retrospective study including all cases of poroid neoplasms registered at our Pathology laboratory of Niamey National Hospital (from February 2020 to February 2024). Results: We registered 13 cases of benign poroid neoplasms: 10 classic poromas (CP) (76.9%), 2 poroid hidradenomas (PH) (15.4%) and 1 dermal duct tumor (DDT) (7.7%). Nine cases (69.2%) had preoperative clinical diagnosis of malignancy. The mean age was 41.1 years (range of 12 – 70 years) with a slight female predominance (sex ratio = 1.16). Only 4/13 cases (30.8%) had classical palmoplantar locations. The tumors mean size was 3.7 cm (range of 0.4 – 8 cm). All cases were well-circumscribed solid (7/13 cases, 53.8%) or solido-cystic whitish nodules (6/13 cases, 46.2%). Clear cells were present in 7 cases (53.8%), apocrine ductal differentiation (mixed or pure) in 6 cases (46.2%), keratin horns in 2 cases (15.4%), squamous eddies in 6 cases (46.2%), melanin pigments in 1 case (7.7%) and sebaceous differentiation in 2 cases (15.4%). Conclusions: Unlike what is classically reported, our study shows that apocrine ductal differentiation, younger age and non-palmoplantar locations are common in poroid neoplasms. Also, PN are often diagnosed as malignant tumors by clinicians before histopathological analysis.

Keywords

Poroid neoplasms; Eccrine poroma; Sweat glands; Apocrine differentiation; Histopathology

Subject

Medicine and Pharmacology, Pathology and Pathobiology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.