Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension: Insights from a Low-Volume Centre and Comparative Analysis with Other Centres

Version 1 : Received: 7 February 2024 / Approved: 8 February 2024 / Online: 8 February 2024 (10:21:40 CET)

A peer-reviewed article of this Preprint also exists.

Ivanauskiene, T.; Cesna, S.; Grigoniene, E.; Gumbiene, L.; Daubaraite, A.; Ivanauskaite, K.; Glaveckaite, S. Balloon Pulmonary Angioplasty for Inoperable Chronic Thromboembolic Pulmonary Hypertension: Insights from a Pilot Low-Volume Centre Study and a Comparative Analysis with Other Centres. Medicina 2024, 60, 461. Ivanauskiene, T.; Cesna, S.; Grigoniene, E.; Gumbiene, L.; Daubaraite, A.; Ivanauskaite, K.; Glaveckaite, S. Balloon Pulmonary Angioplasty for Inoperable Chronic Thromboembolic Pulmonary Hypertension: Insights from a Pilot Low-Volume Centre Study and a Comparative Analysis with Other Centres. Medicina 2024, 60, 461.

Abstract

Background and Objectives: To evaluate the effectiveness and safety of balloon pulmonary angio-plasty in patients with inoperable chronic thromboembolic pulmonary hypertension in Vilnius Pulmonary Hypertension Referral centre and provide comparative analysis with other centres. Materials and Methods. This study included all balloon pulmonary angioplasty procedures per-formed between 2019 and 2024 in a single tertiary centre. Invasive haemodynamic parameters and clinical variables were assessed at baseline, at the end of invasive treatment, and at the con-clusion of follow-up (average 8.6 months) following the last balloon pulmonary angioplasty. Ad-ditionally, respective literature review was performed. Results. Twenty-six patients with inoper-able chronic thromboembolic pulmonary hypertension were enrolled. The mean age of the pa-tients was 61.6 (40-80) years. Each patient underwent an average of 4.2 (1-9) procedures. Fol-low-up data were available for 12 patients. Mean pulmonary arterial pressure decreased by 38.8% (p

Keywords

balloon pulmonary angioplasty; chronic thromboembolic pulmonary hypertension; treatment of inoperable CTEPH

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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