Preprint Case Report Version 2 Preserved in Portico This version is not peer-reviewed

Nodular Neurogenic Tumor of the Tip of the Tongue

Version 1 : Received: 1 February 2024 / Approved: 2 February 2024 / Online: 2 February 2024 (08:50:47 CET)
Version 2 : Received: 2 February 2024 / Approved: 5 February 2024 / Online: 5 February 2024 (05:35:51 CET)

How to cite: Berge, C.; Hafian, H.; Durlach, A. Nodular Neurogenic Tumor of the Tip of the Tongue. Preprints 2024, 2024020130. https://doi.org/10.20944/preprints202402.0130.v2 Berge, C.; Hafian, H.; Durlach, A. Nodular Neurogenic Tumor of the Tip of the Tongue. Preprints 2024, 2024020130. https://doi.org/10.20944/preprints202402.0130.v2

Abstract

Background: Granular cell tumor is a benign neurogenic tumor of the subcutaneous and submucosal area. The tongue is the most affected site of the oral cavity. The clinical presentation is non-specific and manifests as a submucosal nodule or mass. Because of its non-specific presentation, a definitive diagnosis an only be established after a histopathological examination and an immunohistochemical study to search for a neurogenic origin. Methods: We report the case of a 48-year-old man who was referred for the management of a nodular lesion on the tip of his tongue that had increased in size over the previous three months. Results: A complete surgical excision was performed for the histopathological exam, and an immunohistochemical study confirmed a strong expression of S100 and CD68. A diagnosis of granular cell tumor was confirmed. There was no recurrence et three years follow-up. Conclusion: the GCT is a rare tumor of nervous origin of the oral mucosa, it is non-specific in expression, with a good prognosis after complete excision. the histological and immunohistochemical diagnosis of the lesion is essential for the diagnosis.

Keywords

Benign nerve sheath tumors; Abrikossoff’s tumor; granular cell; oral pathologist; peripheral nerve disorders; tongue; s100 protein

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.