Version 1
: Received: 31 January 2024 / Approved: 31 January 2024 / Online: 31 January 2024 (15:02:41 CET)
How to cite:
Liu, X.; He, F.; Liu, M. Shoot the Arrow at the Target: Innovative Stimulus-Responsive Smart Nanocarriers for Cancer Therapy. Preprints2024, 2024012225. https://doi.org/10.20944/preprints202401.2225.v1
Liu, X.; He, F.; Liu, M. Shoot the Arrow at the Target: Innovative Stimulus-Responsive Smart Nanocarriers for Cancer Therapy. Preprints 2024, 2024012225. https://doi.org/10.20944/preprints202401.2225.v1
Liu, X.; He, F.; Liu, M. Shoot the Arrow at the Target: Innovative Stimulus-Responsive Smart Nanocarriers for Cancer Therapy. Preprints2024, 2024012225. https://doi.org/10.20944/preprints202401.2225.v1
APA Style
Liu, X., He, F., & Liu, M. (2024). Shoot the Arrow at the Target: Innovative Stimulus-Responsive Smart Nanocarriers for Cancer Therapy. Preprints. https://doi.org/10.20944/preprints202401.2225.v1
Chicago/Turabian Style
Liu, X., Fang He and Min Liu. 2024 "Shoot the Arrow at the Target: Innovative Stimulus-Responsive Smart Nanocarriers for Cancer Therapy" Preprints. https://doi.org/10.20944/preprints202401.2225.v1
Abstract
With the breakthroughs and innovative developments in nanotechnology, research on the application of nanomedicine in cancer therapy has so far seen tremendous expansion and success. Intelligent stimulus-responsive nanocarriers are an emerging field of research and have great interest in cancer therapy owing to the fascinating properties such as excellent targeting function, high drug loading capacity, and targeted on-demand release properties. Responsive nanomaterials can be designed and constructed according to the dosing context and therapeutic needs, at the same time, activated by internal bio-stimuli (pH, redox, and enzymes) and/or external stimuli (ultrasound, light, temperature, and magnetic), respectively. What’s more, smart nanocarriers are also utilized for the precise and controllable release of antitumor drugs from cancer tissues and cells to achieve efficient diagnosis and treatment of tumors. Deeply investigated, responsive nanocarriers have attracted considerable attention due to their ability to release precisely at tumor-specific sites. Herein, we review the recent advances of novel stimuli-responsive nanocarriers in the field of cancer therapy. Finally, the challenges and application prospects of smart nanocarriers are further elaborately discussed.
Keywords
endogenous stimulus; exogenous stimulus; smart nanocarriers; cancer therapy
Subject
Medicine and Pharmacology, Oncology and Oncogenics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
