Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Recent Advance Bakuchiol Application as a Potential Alternative to Retinol in Skincare and Cosmetics

Version 1 : Received: 18 January 2024 / Approved: 18 January 2024 / Online: 18 January 2024 (07:23:52 CET)

How to cite: Putriana, N.A.; Husni, P.; Mita, S.R. Recent Advance Bakuchiol Application as a Potential Alternative to Retinol in Skincare and Cosmetics. Preprints 2024, 2024011378. https://doi.org/10.20944/preprints202401.1378.v1 Putriana, N.A.; Husni, P.; Mita, S.R. Recent Advance Bakuchiol Application as a Potential Alternative to Retinol in Skincare and Cosmetics. Preprints 2024, 2024011378. https://doi.org/10.20944/preprints202401.1378.v1

Abstract

Herbal cosmetics are cosmetics derived from plants. One example is bakuchiol. Bakuchiol is a meroterpene phenol from the seeds of the Psoralea corylifolia plant. Bakuchiol can be derived from Psoralea grandulosa, Pimelea drupaceae, Ulmus davidiana, Otholobium pubescens, and Piper longum. Bakuchiol has antioxidant, anti-inflammatory, and anti-aging activities such as retinol. Bakuchiol will replace retinol with much better safety. Bakuchiol and retinoids share similar cellular pathways, such as the regulation of retinoic acid, the expression of collagen, and extracellular matrix synthesis enzymes. Bakuchiol has many benefits for the skin, so cosmetics and skin therapy can use bakuchiol. This review aims to provide information about the activity of bakuchiol, which has benefits for facial skin, so that this review can be a reference in making cosmetics containing bakuchiol. Bakuchiol has many benefits for skincare such as anti-aging, anti-hyperpigmentation, anti-oxidant, anti-inflammatory, anti-acne, and anti-melanogenesis. Products containing bakuchiol on the market are cleansers, serum, nanoemulsion, and cream.

Keywords

Bakuchiol; anti-aging; anti-hyperpigmentation; anti-oxidant; anti-inflammatory; anti-acne; and anti-melanogenesis

Subject

Medicine and Pharmacology, Pharmacy

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