Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Current role and future prospects of Positron Emission Tomography (PET)/Computed Tomography (CT) in Management of Breast Cancer

Version 1 : Received: 9 January 2024 / Approved: 9 January 2024 / Online: 9 January 2024 (14:03:16 CET)

A peer-reviewed article of this Preprint also exists.

Robson, N.; Thekkinkattil, D.K. Current Role and Future Prospects of Positron Emission Tomography (PET)/Computed Tomography (CT) in the Management of Breast Cancer. Medicina 2024, 60, 321. Robson, N.; Thekkinkattil, D.K. Current Role and Future Prospects of Positron Emission Tomography (PET)/Computed Tomography (CT) in the Management of Breast Cancer. Medicina 2024, 60, 321.

Abstract

Breast cancer has become the most diagnosed cancer in women globally with 2.3 million new diagnosis each year. Accurate early staging is essential for improving survival rates with metastatic spread from loco regional to distant metastasis decreasing rates by 50%. Current guidelines do not advice the routine use of Positron Emission Tomography (PET)-Computed Tomography (CT) in staging of early breast cancer in the absence of symptoms. However, there is a growing body of evidence to suggest that PET-CT used in this early stage can benefit the patient by improving staging and as a result treatment and outcome as well as psychological burden without increasing costs to the health service. Ongoing research in PET radiomics and artificial intelligence is showing promising future prospects in its use in diagnosis, staging, prognosticatication and assessing response to treatment in breast cancer. Furthermore ongoing research to address current limitations of PET-CT by improving techniques and tracers is encouraging.

Keywords

Breast Cancer, Staging, PET CT, FDG PET, Radiomics, Artificial intelligence

Subject

Medicine and Pharmacology, Surgery

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