Version 1
: Received: 6 January 2024 / Approved: 8 January 2024 / Online: 9 January 2024 (04:04:05 CET)
How to cite:
Otter, J.; Abadioru, O.; Sasson, M.; Gumbrill, B.; Dibbins, M.; Prossomariti, D.; Goldenberg, S. Evaluation of a Novel Hypochlorous Acid Based Hand Hygiene Product With Sporicidal Activity in an Inpatient Ward Setting. Preprints2024, 2024010628. https://doi.org/10.20944/preprints202401.0628.v1
Otter, J.; Abadioru, O.; Sasson, M.; Gumbrill, B.; Dibbins, M.; Prossomariti, D.; Goldenberg, S. Evaluation of a Novel Hypochlorous Acid Based Hand Hygiene Product With Sporicidal Activity in an Inpatient Ward Setting. Preprints 2024, 2024010628. https://doi.org/10.20944/preprints202401.0628.v1
Otter, J.; Abadioru, O.; Sasson, M.; Gumbrill, B.; Dibbins, M.; Prossomariti, D.; Goldenberg, S. Evaluation of a Novel Hypochlorous Acid Based Hand Hygiene Product With Sporicidal Activity in an Inpatient Ward Setting. Preprints2024, 2024010628. https://doi.org/10.20944/preprints202401.0628.v1
APA Style
Otter, J., Abadioru, O., Sasson, M., Gumbrill, B., Dibbins, M., Prossomariti, D., & Goldenberg, S. (2024). Evaluation of a Novel Hypochlorous Acid Based Hand Hygiene Product With Sporicidal Activity in an Inpatient Ward Setting. Preprints. https://doi.org/10.20944/preprints202401.0628.v1
Chicago/Turabian Style
Otter, J., Desiree Prossomariti and Simon Goldenberg. 2024 "Evaluation of a Novel Hypochlorous Acid Based Hand Hygiene Product With Sporicidal Activity in an Inpatient Ward Setting" Preprints. https://doi.org/10.20944/preprints202401.0628.v1
Abstract
Introduction: We under took an in-use evaluation of a novel hypochlorous acid-based hand hygiene product with in vitro sporicidal efficacy in a NHS Older Persons inpatient ward setting. Methods: The novel hand hygiene product was implemented for a trial period of seven weeks commending in September 2023. Healthcare worker (HCW) hands were sampled before and after direct patient care, and after the application of either an alcohol-based handrub (ABHR) (n=50) or the novel product (n=50). Samples were cultured to quantify the total aerobic count (TAC) and presence or absence of MRSA, ESBLs, CREs, and C. difficile. Trends in weekly observational hand hygiene audit results were reviewed, and a survey of HCW views about the new product undertaken. Results: HCW hands had a significantly greater TAC after ABHR (p=0.01) but not after the novel product (p=0.11) compared with their respective baseline counts. 3% of 100 samples grew MRSA or ESBLs after application of the alcohol-based or novel hand hygiene products. No C. difficile was cultured from healthcare worker hands. There was no significant difference in observed hand hygiene compliance. The majority of HCW surveyed preferred the novel product to the alcohol-based hand hygiene product. Discussion: The novel hand hygiene product was more effective than ABHR at reducing the TAC on HCW hands. Poor hand hygiene technique may explain the identification of antibiotic-resistant bacteria on staff hands after ABHR or the novel product. We were not able to evaluate sporicidal efficacy since no C. difficile was cultured from hands.
Keywords
hand hygiene; microbiology; hypochlorous acid; antibiotic resistance
Subject
Medicine and Pharmacology, Epidemiology and Infectious Diseases
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
