PreprintReviewVersion 1Preserved in Portico This version is not peer-reviewed
The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review
Version 1
: Received: 7 January 2024 / Approved: 8 January 2024 / Online: 8 January 2024 (06:50:25 CET)
How to cite:
Tripathi, M.; Bhardwaj, P.; Tiwari, S.; Sahu, A. The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review. Preprints2024, 2024010554. https://doi.org/10.20944/preprints202401.0554.v1
Tripathi, M.; Bhardwaj, P.; Tiwari, S.; Sahu, A. The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review. Preprints 2024, 2024010554. https://doi.org/10.20944/preprints202401.0554.v1
Tripathi, M.; Bhardwaj, P.; Tiwari, S.; Sahu, A. The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review. Preprints2024, 2024010554. https://doi.org/10.20944/preprints202401.0554.v1
APA Style
Tripathi, M., Bhardwaj, P., Tiwari, S., & Sahu, A. (2024). The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review. Preprints. https://doi.org/10.20944/preprints202401.0554.v1
Chicago/Turabian Style
Tripathi, M., Shruti Tiwari and Arti Sahu. 2024 "The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review" Preprints. https://doi.org/10.20944/preprints202401.0554.v1
Abstract
The last 20 years have seen significant advancements in polymeric drug delivery methods. A formulation or a system that makes it possible for a medicinal ingredient to be injected into the body is known as polymeric drug delivery1. The key choice for many novel medication delivery methods is made achievable by biodegradable and bio-reducible polymers. The research's prospects for practical applications have necessitated the field's development—the choice for a lot of new drug delivery systems. The prospects of the research for practical applications are required for the development in the field. Polymeric drug delivery methods have been developed from natural polymers like arginine, chitosan2, dextrin, polysaccharides, poly (glycolic acid), poly (lactic acid), and hyaluronic acid. Regarding polymeric drug delivery1, synthetic polymers such as poly(2-hydroxyethyl methacrylate), poly(N-isopropyl acrylamide), poly(ethylenimine), dendritic polymers, biodegradable, and bioabsorbable polymers have all been considered. Polymeric drug delivery has also been addressed by focusing on drug-free macromolecular therapies, biomimetic and bio-related polymeric systems, and targeting polymeric drug delivery. Pharmaceutical fields are seeing a tremendous rise in the development of polymeric drug delivery methods based on natural and manmade polymers. The successful advancements in the utilization of biocompatible and bio-related copolymers and dendrimers in cancer treatment, including their application as vehicle systems for highly effective anticancer medications3. A new paradigm for the development of polymeric drug and gene delivery systems will be possible through the fusion of viewpoints from the synthetic and biological domains.
Keywords
Biodegradable Polymers; Nanotechnology; Drug Delivery & Drug Development
Subject
Medicine and Pharmacology, Pharmacy
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
