Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Needless Electrospun Collagen/Hyaluronic Acid Nanofibers for Skincare Applications: Research

Version 1 : Received: 30 December 2023 / Approved: 3 January 2024 / Online: 4 January 2024 (05:57:22 CET)

How to cite: Tören, E.; Mazari, A. Needless Electrospun Collagen/Hyaluronic Acid Nanofibers for Skincare Applications: Research. Preprints 2024, 2024010272. https://doi.org/10.20944/preprints202401.0272.v1 Tören, E.; Mazari, A. Needless Electrospun Collagen/Hyaluronic Acid Nanofibers for Skincare Applications: Research. Preprints 2024, 2024010272. https://doi.org/10.20944/preprints202401.0272.v1

Abstract

This study investigated the potential of electrospun collagen/Hyaluronic Acid nanofibers in biomedicine and skincare. Needleless electrospinning technology employed in the production process resulted in nanofibers with consistent fiber diameters and improved mechanical properties. The composite nanofibers demonstrated impressive tensile strength and elongation capabilities, indicating a favorable interaction between collagen and HA. Cellular assays revealed that the collagen/HA scaffolds facilitated superior cell adhesion and proliferation compared to the control scaffolds, indicating their biocompatibility and potential for tissue engineering. This biomaterial offers an environment-friendly alternative to conventional skincare products by eliminating the need for preservatives and reducing waste. Although the initial costs are high, the long-term benefits of material durability and active ingredient efficacy provide a compelling case for industrial adoption. Our findings suggest that collagen/HA nanofibers have the potential to be next-generation materials for regenerative medicine and skincare, and further research is needed to optimize their production and assess the economic feasibility of skincare and tissue engineering applications.

Keywords

electrospinning; collagen/hyaluronic acid nanofibers; biomaterials; skincare applications

Subject

Chemistry and Materials Science, Biomaterials

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